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DAPK2 encodes a protein that belongs to the serine/threonine protein kinase family. Additionally we are shipping DAPK2 Proteins (5) and many more products for this protein.
Showing 10 out of 145 products:
Human Polyclonal DAPK2 Primary Antibody for IHC (p), WB - ABIN1882166
Satoh, Toyota, Itoh, Kikuchi, Obata, Sasaki, Suzuki, Yawata, Kusano, Fujita, Hosokawa, Yanagihara, Tokino, Imai: DNA methylation and histone deacetylation associated with silencing DAP kinase gene expression in colorectal and gastric cancers. in British journal of cancer 2002
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Human Polyclonal DAPK2 Primary Antibody for EIA, IHC (p) - ABIN359412
Chan, Chan, Tang, Tong, Lo, Lee, Cheung, Wong, Chan, Lai, To: Hypermethylation of multiple genes in tumor tissues and voided urine in urinary bladder cancer patients. in Clinical cancer research : an official journal of the American Association for Cancer Research 2002
Show all 4 references for ABIN359412
Human Polyclonal DAPK2 Primary Antibody for EIA, IHC (p) - ABIN499708
Kawai, Nomura, Hoshino, Copeland, Gilbert, Jenkins, Akira: Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity. in Oncogene 1999
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Human Polyclonal DAPK2 Primary Antibody for WB - ABIN658632
Zambrowicz, Abuin, Ramirez-Solis, Richter, Piggott, BeltrandelRio, Buxton, Edwards, Finch, Friddle, Gupta, Hansen, Hu, Huang, Jaing, Key, Kipp, Kohlhauff, Ma, Markesich, Payne, Potter, Qian, Shaw et al.: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. ... in Proceedings of the National Academy of Sciences of the United States of America 2003
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Human Polyclonal DAPK2 Primary Antibody for IHC (p), IHC - ABIN257703
Geering, Stoeckle, Rozman, Oberson, Benarafa, Simon: DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants. in Journal of leukocyte biology 2014
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Human Polyclonal DAPK2 Primary Antibody for IHC, ELISA - ABIN1532591
Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006
Show all 2 references for ABIN1532591
Human Polyclonal DAPK2 Primary Antibody for IHC (p), WB - ABIN391322
Shani, Henis-Korenblit, Jona, Gileadi, Eisenstein, Ziv, Admon, Kimchi: Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin binding. in The EMBO journal 2001
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Human Polyclonal DAPK2 Primary Antibody for IHC (p), WB - ABIN303251
Colvard, Wilson: Zinc potentiation of androgen receptor binding to nuclei in vitro. in Biochemistry 1984
miR (show MLXIP Antibodies)-520h suppresses Death-associated protein kinase 2 (DAPK2) expression, as restoring DAPK2 abolished miR (show MLXIP Antibodies)-520h-promoted drug resistance, and knockdown of DAPK2 mitigated cell death caused by the depletion of miR (show MLXIP Antibodies)-520h.
that Death-associated protein kinase 2 effector functions are influenced by the protein's subcellular localization
This study links adipocyte expression of an autophagy-regulating kinase, lysosome-mediated clearance and fat cell lipid accumulation; it demonstrates obesity-related attenuated autophagy in adipocytes, and identifies DAPK2 dependence in this regulation.
DAPK2 is a novel kinase of mTORC1 and is a potential new member of this multiprotein complex, modulating mTORC1 activity and autophagy levels under stress and steady-state conditions.
DAPK2 regulates oxidative stress in cancer cells by preserving mitochondrial function
DAPK2-induced apoptosis is negatively regulated by Akt (show AKT1 Antibodies) and 14-3-3 (show YWHAQ Antibodies) proteins.
DAPK2 is upregulated in uterosacral ligaments in pelvic organ prolapse
The defect in chemotaxis in DAPK2-inactive granulocytes is likely a result of reduced polarization of the cells, mediated by a lack of MLC phosphorylation, resulting in radial F-actin and pseudopod formation.
The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPalpha (show CEBPA Antibodies) during granulocytic differentiation but repressed by PML (show PML Antibodies)-RARalpha (show RARA Antibodies) in APL (show FASL Antibodies).
DRP-1 (show CRMP1 Antibodies) and ZIPk (show DAPK3 Antibodies) most likely evolved from their ancient ancestor gene DAPk (show DAPK1 Antibodies) by two gene duplication events that occurred close to the emergence of vertebrates
DAPK2 is strongly and specifically expressed in interstitial cells of the cortex, providing a useful marker for this important cell population
These results suggest that DAPK2 is one of the targets of cGK (show PRKG1 Antibodies)-I in apoptosis induction.
The crystal and solution structures of murine DAPK2 were determined in the presence of the autoinhibitory domain, with and without bound nucleotides in the active site. Dimers of DAPK2 had a conformation that did not permit protein substrate binding.
DAPK2 was substantially up-modulated during late erythropoiesis
This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites.
death-associated protein kinase 2
, DAP kinase 2
, DAP-kinase-related protein 1 beta isoform
, death-associated kinase 2