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anti-Dedicator of Cytokinesis 4 (DOCK4) Antibodies

DOCK4 is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. Additionally we are shipping DOCK4 Kits (5) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DOCK4 238130 P59764
DOCK4 9732 Q8N1I0
DOCK4    
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Top anti-DOCK4 Antibodies at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to DOCK4 on formalin-fixed paraffin-embedded human breast cancer. [antibody concentration 3 ug/ml] DOCK4 monoclonal antibody (M01), clone 3E7 Western Blot analysis of DOCK4 expression in Hela NE 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated WB DOCK4 monoclonal antibody (M03), clone 1B3. Western Blot analysis of DOCK4 expression in PC-12. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA, WB DOCK4 monoclonal antibody (M01A), clone 3E7 Western Blot analysis of DOCK4 expression in Hela NE DOCK4 monoclonal antibody (M01A), clone 3E7. Western Blot analysis of DOCK4 expression in HeLa. 200 μL Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to DOCK4 on HeLa cell (antibody concentration 10 µg/mL). DOCK4 monoclonal antibody (M01), clone 3E7 Western Blot analysis of DOCK4 expression in Hela NE. 0.05 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IF, ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

DOCK4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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Top referenced anti-DOCK4 Antibodies

  1. Human Monoclonal DOCK4 Primary Antibody for IF, IHC (p) - ABIN564203 : Eiring, Neviani, Santhanam, Oaks, Chang, Notari, Willis, Gambacorti-Passerini, Volinia, Marcucci, Caligiuri, Leone, Perrotti: Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis. in Blood 2008 (PubMed)

More Antibodies against DOCK4 Interaction Partners

Mouse (Murine) Dedicator of Cytokinesis 4 (DOCK4) interaction partners

  1. Dock4 binds to SH3YL1 through the C-terminal proline-rich region.

  2. The Atypical guanine nucleotide exchange factor Dock4 regulates neurite differentiation through modulation of Rac1 GTPase and actin dynamics.

  3. Rac-DOCK4-actin-binding protein harmonin-activated signaling pathway is possibly involved in regulating actin cytoskeleton organization in stereocilia of the inner ear.

Human Dedicator of Cytokinesis 4 (DOCK4) interaction partners

  1. DOCK4 signalling is necessary for lateral filopodial protrusions and tubule remodelling prior to vascular lumen formation

  2. These data identify DOCK4 as a putative 7q gene whose reduced expression can lead to erythroid dysplasia

  3. activator DOCK4 as a key component of the TGF-beta (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies) pathway that promotes lung ADC (show ADC Antibodies) cell extravasation and metastasis.

  4. The study found significant associations between autism and a SNP of the DOCK4 gene.

  5. The Atypical guanine nucleotide exchange factor Dock4 regulates neurite differentiation through modulation of Rac1 GTPase and actin dynamics.

  6. novel epigenetic alterations in myelodysplastic leukocytes and implicate DOCK4 as a pathogenic gene located on the 7q chromosomal region.

  7. Evidence for the involvement of DOCK4 in autism susceptibility was supported by independent replication of association at rs2217262 and the finding of a deletion segregating in a sib-pair family

  8. Data suggest that exonic deletions of DOCK4 may act as a risk factor for reading impairment. Genomic disruption of both DOCK4 and CNTNAP5 genes may have an additive effect and may result in a more severe autism spectrum phenotype.

  9. Taken together, these results suggest that Dock4 plays an important role in the regulation of cell migration through activation of Rac1, and that RhoG (show RHOG Antibodies) is a key upstream regulator for Dock4.

  10. DOCK4 may be regulated by PIP(3) to exert its function

DOCK4 Antigen Profile

Protein Summary

This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized.

Gene names and symbols associated with DOCK4

  • dedicator of cytokinesis 4 (DOCK4) antibody
  • dedicator of cytokinesis 4 (NAEGRDRAFT_81257) antibody
  • dedicator of cytokinesis 4 (LOC100355539) antibody
  • dedicator of cytokinesis 4 (Dock4) antibody
  • 5330406C03 antibody
  • 6330411N01Rik antibody
  • AF263288 antibody
  • C030023J22 antibody
  • DOCK4 antibody
  • mKIAA0716 antibody

Protein level used designations for DOCK4

dedicator of cytokinesis 4 , dedicator of cytokinesis protein 4-like , dedicator of cytokinesis protein 4

GENE ID SPECIES
463661 Pan troglodytes
703726 Macaca mulatta
8858503 Naegleria gruberi strain NEG-M
100055674 Equus caballus
100355539 Oryctolagus cuniculus
100406117 Callithrix jacchus
100464976 Ailuropoda melanoleuca
100547814 Meleagris gallopavo
100604748 Nomascus leucogenys
238130 Mus musculus
9732 Homo sapiens
417779 Gallus gallus
482407 Canis lupus familiaris
100520706 Sus scrofa
534227 Bos taurus
Selected quality suppliers for anti-DOCK4 (DOCK4) Antibodies
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