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Dedicator of Cytokinesis 4 (DOCK4) ELISA Kits

DOCK4 is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. Additionally we are shipping DOCK4 Antibodies (33) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse DOCK4 DOCK4 238130 P59764
DOCK4 9732 Q8N1I0
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Top DOCK4 ELISA Kits at antibodies-online.com

Showing 1 out of 5 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.063 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details

More ELISA Kits for DOCK4 Interaction Partners

Mouse (Murine) Dedicator of Cytokinesis 4 (DOCK4) interaction partners

  1. Dock4 binds to SH3YL1 through the C-terminal proline-rich region.

  2. The Atypical guanine nucleotide exchange factor Dock4 regulates neurite differentiation through modulation of Rac1 GTPase and actin dynamics.

  3. Rac-DOCK4-actin-binding protein harmonin-activated signaling pathway is possibly involved in regulating actin cytoskeleton organization in stereocilia of the inner ear.

Human Dedicator of Cytokinesis 4 (DOCK4) interaction partners

  1. DOCK4 signalling is necessary for lateral filopodial protrusions and tubule remodelling prior to vascular lumen formation

  2. These data identify DOCK4 as a putative 7q gene whose reduced expression can lead to erythroid dysplasia

  3. activator DOCK4 as a key component of the TGF-beta (show TGFB1 ELISA Kits)/Smad (show SMAD1 ELISA Kits) pathway that promotes lung ADC (show ADC ELISA Kits) cell extravasation and metastasis.

  4. The study found significant associations between autism and a SNP of the DOCK4 gene.

  5. The Atypical guanine nucleotide exchange factor Dock4 regulates neurite differentiation through modulation of Rac1 GTPase and actin dynamics.

  6. novel epigenetic alterations in myelodysplastic leukocytes and implicate DOCK4 as a pathogenic gene located on the 7q chromosomal region.

  7. Evidence for the involvement of DOCK4 in autism susceptibility was supported by independent replication of association at rs2217262 and the finding of a deletion segregating in a sib-pair family

  8. Data suggest that exonic deletions of DOCK4 may act as a risk factor for reading impairment. Genomic disruption of both DOCK4 and CNTNAP5 (show CNTNAP5 ELISA Kits) genes may have an additive effect and may result in a more severe autism spectrum phenotype.

  9. Taken together, these results suggest that Dock4 plays an important role in the regulation of cell migration through activation of Rac1, and that RhoG (show RHOG ELISA Kits) is a key upstream regulator for Dock4.

  10. DOCK4 may be regulated by PIP(3) to exert its function

DOCK4 Antigen Profile

Antigen Summary

This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized.

Gene names and symbols associated with DOCK4

  • dedicator of cytokinesis 4 (DOCK4) antibody
  • dedicator of cytokinesis 4 (NAEGRDRAFT_81257) antibody
  • dedicator of cytokinesis 4 (LOC100355539) antibody
  • dedicator of cytokinesis 4 (Dock4) antibody
  • 5330406C03 antibody
  • 6330411N01Rik antibody
  • AF263288 antibody
  • C030023J22 antibody
  • DOCK4 antibody
  • mKIAA0716 antibody

Protein level used designations for DOCK4

dedicator of cytokinesis 4 , dedicator of cytokinesis protein 4-like , dedicator of cytokinesis protein 4

GENE ID SPECIES
463661 Pan troglodytes
703726 Macaca mulatta
8858503 Naegleria gruberi strain NEG-M
100055674 Equus caballus
100355539 Oryctolagus cuniculus
100406117 Callithrix jacchus
100464976 Ailuropoda melanoleuca
100547814 Meleagris gallopavo
100604748 Nomascus leucogenys
238130 Mus musculus
9732 Homo sapiens
417779 Gallus gallus
482407 Canis lupus familiaris
100520706 Sus scrofa
534227 Bos taurus
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