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Guanine nucleotide exchange factor (GEF) for Rho and Rac. Additionally we are shipping and many more products for this protein.
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The fusion of embryonic fast-twitch myoblasts requires the activities of Dock1 (show DOCK1 Antibodies) and the closely related Dock5 protein.
the potential role of DOCK5 in human obesity
along with DOCK1 (show DOCK1 Antibodies), DOCK5 is an important mediator of CrkII (show CRK Antibodies)/CrkL (show CRKL Antibodies) regulation of Caco-2 spreading and migration on collagen IV (show COL4 Antibodies).
Dock5 and tensin 3 (show TNS3 Antibodies) cooperate for osteoclast activity, to ensure the correct organization of podosomes.
Tensin3 (show TNS3 Antibodies) is a versatile regulator of DOCK5 signaling and cell adhesion. (Review)
together with DOCK2 (show DOCK2 Antibodies) contributes to chemotaxis, reactive oxygen species production, and extracellular trap formation
Dock1 (show DOCK1 Antibodies) and Dock5 are not the important exchange factors regulating Rac (show AKT1 Antibodies) activity during the establishment and maintenance of the glomerular barrier
results thus identify DOCK5 as a key signaling adaptor that orchestrates remodeling of the microtubule network essential for mast cell degranulation.
The atypical Rac1 exchange factor Dock5 is necessary for osteoclast function both in vitro and in vivo.
Cataract causing lr2 gene is found in the CXSD mouse, which is a recombinant inbred strain of BALB/c and STS (show STS Antibodies) mice
Dock5 is dispensable for normal mouse embryogenesis and contribution of Dock5 toward myofiber development.
Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP.
dedicator of cytokinesis 5
, Dedicator of cytokinesis 5-like
, dedicator of cytokinesis protein 5
, dedicator of cytokinesis protein 5-like
, lens rupture 2
, lens rupture protein 2
, rupture of lens cataract protein