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Dedicator of Cytokinesis 6 (DOCK6) ELISA Kits

DOCK6 encodes a member of the dedicator of cytokinesis (DOCK) family of atypical guanine nucleotide exchange factors. Additionally we are shipping and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human DOCK6 DOCK6 57572 Q96HP0
Anti-Mouse DOCK6 DOCK6 319899 Q8VDR9
Anti-Rat DOCK6 DOCK6 367039  
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More ELISA Kits for DOCK6 Interaction Partners

Cow (Bovine) Dedicator of Cytokinesis 6 (DOCK6) interaction partners

  1. Dock6 may be involved in the development of cystic follicles by suppressing P4 production rather than increasing A4 production in theca cells

Human Dedicator of Cytokinesis 6 (DOCK6) interaction partners

  1. this study demonstrates that miR (show MLXIP ELISA Kits)-142-3p is a key regulator of the TGFbeta (show TGFB1 ELISA Kits)-mediated contractile phenotype of VSMCs that acts through inhibiting cell migration through targeting DOCK6.

  2. DOCK6 mutations are responsible for a distinct autosomal-recessive variant of Adams-Oliver syndrome associated with brain and eye anomalies

  3. A homozygous truncating mutation in dedicator of cytokinesis 6 gene (DOCK6) which encodes an atypical guanidine exchange factor (GEF) known to activate two members of the Rho GTPase family: Cdc42 and Rac1, was identified.

Mouse (Murine) Dedicator of Cytokinesis 6 (DOCK6) interaction partners

  1. phosphorylation status of Dock6 at Ser(1194) determines whether it promotes axon extension or branching in sensory neurons, revealing interplay between kinase and phosphatase action on a Rho-GEF during axon growth

  2. Dock6 is the GEF (show ARHGEF2 ELISA Kits) specific for both Rac1 and Cdc42 (show CDC42 ELISA Kits) and may be one of physiological regulators of neurite outgrowth.

DOCK6 Antigen Profile

Antigen Summary

This gene encodes a member of the dedicator of cytokinesis (DOCK) family of atypical guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with small GTPases and are components of intracellular signaling networks. The encoded protein is a group C DOCK protein and plays a role in actin cytoskeletal reorganization by activating the Rho GTPases Cdc42 and Rac1. Mutations in this gene are associated with Adams-Oliver syndrome 2.

Gene names and symbols associated with DOCK6

  • dedicator of cytokinesis 7 (dock7) antibody
  • dedicator of cytokinesis 6 (DOCK6) antibody
  • dedicator of cytokinesis 6 (dock6) antibody
  • dedicator of cytokinesis 6 (Dock6) antibody
  • 2410095B20Rik antibody
  • 4931431C02Rik antibody
  • AOS2 antibody
  • C330023D02Rik antibody
  • dock6 antibody
  • mKIAA1395 antibody
  • ZIR1 antibody
  • zir2 antibody

Protein level used designations for DOCK6

dedicator of cytokinesis 7 , dedicator of cytokinesis 6 , dedicator of cytokinesis protein 6

GENE ID SPECIES
443597 Xenopus laevis
508023 Bos taurus
611163 Canis lupus familiaris
716279 Macaca mulatta
100057307 Equus caballus
100127844 Xenopus (Silurana) tropicalis
716191 Macaca mulatta
57572 Homo sapiens
319899 Mus musculus
367039 Rattus norvegicus
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