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novel thyroid transcript negatively regulated by thyroid stimulating hormone. Additionally we are shipping Dedicator of Cytokinesis 9 Antibodies (16) and and many more products for this protein.
c.2262A>C substitution in DOCK9 leads to a splicing aberration. However, because the mutation effect was observed in vitro, a definitive relationship between DOCK9 and KTCN (show VSX1 ELISA Kits) phenotype could not be established.
Studies indicate that that many of the mechanistic principles of the exchange process are conserved in the DOCK9-catalyzed reaction.
Sequence comparison combined with mutational analysis identified a new domain, which we named CZH2, that mediates direct interaction with Cdc42 (show CDC42 ELISA Kits)
DOCK9 contributes to both risk and increased illness severity in bipolar disorder.
novel functions for the N-terminal region of zizimin1.
DOCK2 (show DOCK2 ELISA Kits) and DOCK9 specifically recognize Rac2 (show RAC2 ELISA Kits) and Cdc42 (show CDC42 ELISA Kits) through their switch 1 as well as beta2-beta3 regions and the mode of recognition via switch 1 appears to be conserved among diverse Rac (show AKT1 ELISA Kits)-specific DHR-2 GEFs
interaction between Smad2 (show SMAD2 ELISA Kits)/3 and the Cdc42 (show CDC42 ELISA Kits) guanine nucleotide exchange factor (show RASGRF1 ELISA Kits), Zizimin1, in response to TGF-beta1 (show TGFB1 ELISA Kits)
through structural analysis of DOCK9-Cdc42 (show CDC42 ELISA Kits) complexes, we identify a nucleotide sensor within the alpha10 helix of the DHR2 domain that contributes to release of guanine diphosphate (GDP) and then to discharge of the activated GTP (show AK3 ELISA Kits)-bound Cdc42 (show CDC42 ELISA Kits)
Thus, these results suggest that Zizimin1 plays an important role in dendrite growth in hippocampal neurons through activation of Cdc42 (show CDC42 ELISA Kits).
novel thyroid transcript negatively regulated by thyroid stimulating hormone
dedicator of cytokinesis 9
, dedicator of cytokinesis protein 9
, Dedicator of cytokinesis protein 9
, dedicator of cytokinesis protein 9-like
, cdc42 guanine nucleotide exchange factor zizimin-1
, Thyroid regulating