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Defensin, alpha 1 Proteins (DEFA1)

Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Additionally we are shipping alpha Defensin 1 Antibodies (53) and alpha Defensin 1 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DEFA1 1667 P59665
Mouse DEFA1 DEFA1 13216 P11477
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Top alpha Defensin 1 Proteins at

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast REACT_Pea His tag   1 mg Log in to see 56 to 66 Days
Yeast REACT_Apis mellifera His tag   1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 11 to 16 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

DEFA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,

More Proteins for Defensin, alpha 1 (DEFA1) Interaction Partners

Human Defensin, alpha 1 (DEFA1) interaction partners

  1. the decreased HNP-1 production in the polymorphonuclear phagocytes form elderly individuals might have an important participation in the increased susceptibility to infectious diseases.

  2. Increased levels of neutrophil defensin 1, apolipoprotein E (show APOE Proteins), clusterin (show CLU Proteins), and zinc-alpha-2-glycoprotein (show AZGP1 Proteins) are present in carotid atherosclerotic plaque secretomes.

  3. HNP1 functions as a "molecular brake" on macrophage-driven inflammation, ensuring both pathogen clearance and the resolution of inflammation with minimal bystander tissue damage.

  4. HP1 binding to the chromosomal passenger complex becomes particularly important when Aurora B (show AURKB Proteins) phosphorylates kinetochore targets to eliminate erroneous microtubule attachments

  5. data demonstrate that HNP-1 induces IL-8 production not only through P2Y6, but also through additional P2 receptors via an ERK1/2-dependent mechanism in intestinal epithelial cells.

  6. Results showed that NO and NaNO2 can be considered as factors regulating the chemoattractant properties of defensin (show DEF Proteins) HNP1 in neutrophils

  7. Overexpression of DEFA1 retained independent prognostic significance for B-ALL outcome.

  8. Defensins promote the differentiation into activated CD91 (show LRP1 Proteins)(bright) dendritic cells.

  9. Elevated DEFA1 levels in diabetes are independent of DEFA1 copy numbers.

  10. binding of HNP1 to affected bacterial toxins caused their local unfolding, potentiated their thermal melting and precipitation, exposed new regions for proteolysis, and increased susceptibility to collisional quenchers.

Mouse (Murine) Defensin, alpha 1 (DEFA1) interaction partners

  1. Decreased alpha-defensin (show DEF Proteins) is associated with intestinal inflammation in a model of inflammatory bowel disease.

  2. cryptdin-1 and cryptdin-4 exhibit circadian oscillation

  3. the Arg5-Glu13 salt bridge in alpha-defensin (show DEF Proteins) is conserved for defensin (show DEF Proteins) in vivo stability

  4. MMP-7 (show MMP7 Proteins) activates mouse paneth cell pro-alpha-defensins

alpha Defensin 1 (DEFA1) Protein Profile

Protein Summary

Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.

Gene names and symbols associated with Defensin, alpha 1 Proteins (DEFA1)

  • defensin, alpha 1 (DEFA1)
  • defensin 1 (Def1)
  • defensin, alpha 1 (Defa1)
  • defensin, alpha 1B (DEFA1B)
  • Def protein
  • DEF1 protein
  • DEFA1 protein
  • DEFA2 protein
  • Defcr protein
  • Defcr1 protein
  • GB19392 protein
  • HNP-1 protein
  • HP-1 protein
  • HP1 protein
  • MRS protein

Protein level used designations for Defensin, alpha 1 Proteins (DEFA1)

alpha-defensin 1 , defensin alpha 1 , defensin alpha 2 , Paneth cell-specific alpha-defensin 2 , defensin-1 , royalisin , defensin, alpha 1, myeloid-related sequence , defensin, alpha 2 , myeloid-related sequence , neutrophil defensin 1 , cryptdin-1 , defensin related cryptdin peptide 1 , defensin-related cryptdin peptide

100126731 Papio anubis
100126732 Papio anubis
100307002 Equus caballus
406143 Apis mellifera
1667 Homo sapiens
13216 Mus musculus
742808 Pan troglodytes
728358 Homo sapiens
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