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Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Additionally we are shipping beta Defensin 1 Proteins (48) and beta Defensin 1 Kits (36) and many more products for this protein.
Showing 10 out of 171 products:
Human Monoclonal beta Defensin 1 Primary Antibody for EIA, WB - ABIN192005
Breuckmann, von Kobyletzki, Avermaete, Pieck, Kreuter, Brockmeyer, Altmeyer, Gambichler: Mononuclear cells in atopic dermatitis in vivo: immunomodulation of the cutaneous infiltrate by medium-dose UVA1 phototherapy. in European journal of medical research 2002
Stimulation of umbilical-vein endothelial cells with S. aureus or LPS (show IRF6 Antibodies) induced the expression of bovine beta-defensin 1. This expression was regulated by the autocrine production of tumor necrosis factor-alpha (show TNF Antibodies).
The synthetic peptides bovine enteric beta-defensin (EBD), bovine neutrophil beta-defensin (BNBD) 9 and BNBD 3 are chemotactic for immature dendritic cells.(
Fenofibrate and gemfibrozil inhibit LPS (show TLR4 Antibodies)-induced inflammatory activation of macrophages via PPARalpha (show PPARA Antibodies)/beta-defensin 1/TLR4 (show TLR4 Antibodies) pathway.
these studies demonstrate a role for the murine beta-defensin 1 peptide in early control of Candida infection in a murine model of mucosal candidiasis
Akt1 (show AKT1 Antibodies) is involved in the regulation of defensin (show DEF Antibodies) expression and the innate immune response important for bacterial clearance
Histopathology showed a greater inflammatory influx in the lungs of mBD-1((-/-)) mice at Day 3 postinfection compared with WT C57BL/6 mice
The decreased production of antimicrobial peptides by burn-site epidermal keratinocytes influenced by Gr-1 (show GSR Antibodies)(+)CD11b (show ITGAM Antibodies)(+) cells was shown to be restored by glycyrrhizin.
elimination of mBD-1 results in a defect in the ability of the host to clear H. influenzae from the lung, which is most consistent with this peptide functioning as an antibiotic at the airway surface.
The expression of BD1 was significantly elevated in the lungs of cigarette smoke-exposed mice compared with air-exposed mice.
Although both murine beta-defensin (mBD)-1 and mBD2 (show MBD2 Antibodies) are constitutively expressed in normal BALB/c and C57BL/6 corneas, mBD-1 is not required for host resistance against Pseudomonas aeruginosa-induced corneal infection.
DEFB1 polymorphisms alone may not influence pathology susceptibility, however they could possibly concur, together with other factors involved in the genetic control of innate immune system, in the predisposition towards recurrent tonsillitis
beta-defensin-1 production is dysregulated in the epithelium of patients with chronic obstructive pulmonary disease
dental plaque amount, lactobacilli count, age, and saliva (show RAG1AP1 Antibodies) buffer capacity, as well as DEFB1 gene polymorphism, explained a total of 87.8% of variations in DMFT scores.
Our meta-analysis provides evidence that DEFB1 genetic polymorphisms rs11362G>A, rs1800972C>G and rs1799946G>A are important contributing factors to the development of digestive diseases
Association of infectious pathology of upper respiratory tract and development of periodontitis diseases with markers in DEFB1 (-44G/C) and TLR2 (show TLR2 Antibodies) Arg753Gln and Arg677Trp genes was determined.
Genotypes and alleles of the DEFB1 gene found in long-living individuals can be considered as the factors that increase the probability of longevity and favorable course of age-related diseases.
Possible association between DEFB1 polymorphisms and in vivo salivary levels of hBD-1 in an Italian population of 40 healthy individuals, finding a genotype-related different expression with two of these polymorphisms: -52G > A and -44C > G.
We found that RNA interference-induced Caspase-12 (show CASP12 Antibodies) silencing increased NOD1 (show NOD1 Antibodies), hBD1 and hBD2 (show DEFB4 Antibodies) expression
A-dependent DEFB1 upregulation below 20 mM predicts in vitro antimicrobial activity as well as glucose- and AA-dependent CAMP and IFNG (show IFNG Antibodies) upregulation.
The DEFB1 c.-44C>G polymorphism of the GG protective genotype was much less frequent among multiple sclerosis patients than among the controls.
pBD1 showed low hemolytic activity and high thermal stability. These properties are relevant for the biotechnological applications of the peptide.
Zinc sulfate and L-isoleucine induce beta defensin expression in a porcine cell line.
Presence of beta-defensin 1 in the upper respiratory tract is associated with resistance against respiratory infection with Bordetella pertussis in older piglets
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.
, antimicrobial peptide-3
, beta-defensin 1
, beta-defensin 3
, beta-defensin prepropeptide
, Beta-defensin 1
, Defensin, beta 1
, prepro-beta-defensin 1
, defensin, beta 1 (enteric)
, enteric beta-defensin
, enteric prepro-beta-defensin
, beta defensin-1 homolog
, Gal 1
, Gal 1-alpha
, antimicrobial peptide 1
, antimicrobial peptide CHP2
, chicken heterophil peptide 2
, gal-1 alpha
, gallinacin-1 alpha