Defensin, beta 4A Proteins (DEFB4)

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Additionally we are shipping Defensin, beta 4A Antibodies (50) and Defensin, beta 4A Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse DEFB4 DEFB4 13215 P82020
Rat DEFB4 DEFB4 641631  
DEFB4 1673 O15263
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Top Defensin, beta 4A Proteins at antibodies-online.com

Showing 8 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 20 μg Log in to see 3 to 4 Days
$150.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 4 Days
$280.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 6 to 8 Days
$328.21
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   1 mg Log in to see 2 to 3 Days
$3,500.00
Details
Yeast Macaca mulatta His tag   1 mg Log in to see 60 to 71 Days
$1,991.00
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 60 to 71 Days
$1,991.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   0.005 mg Log in to see 2 to 3 Days
$178.75
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 2 to 3 Days
$376.79
Details

DEFB4 Proteins by Origin and Source

Origin Expressed in
Human

More Proteins for Defensin, beta 4A (DEFB4) Interaction Partners

Pig (Porcine) Defensin, beta 4A (DEFB4) interaction partners

  1. The results demonstrate that transgenic overexpression of PBD-2 in pigs confers enhanced resistance against Actinobacillus pleuropneumoniae infection.

  2. Zinc sulfate and L-isoleucine induce beta defensin (show DEFB1 Proteins) expression in a porcine cell line.

  3. pBD-2 may be an important defense molecule for intestinal health.

Turkey Defensin, beta 4A (DEFB4) interaction partners

Mouse (Murine) Defensin, beta 4A (DEFB4) interaction partners

  1. Giardia co-infection promotes the secretion of antimicrobial peptides beta-defensin 2 and trefoil factor 3 (show TFF3 Proteins) and attenuates attaching and effacing bacteria-induced intestinal disease.

  2. NOD2-mediated beta-defensin 2 regulation contributes to the protection against NTHi-induced otitis media

  3. mouse urothelium produces mBD2 (show MBD2 Proteins) in response to intravesicular BCG (show SLC11A1 Proteins) as a defense mechanism against BCG (show SLC11A1 Proteins)

  4. visfatin (show NAMPT Proteins) enhances CAMP, hBD-2, hBD-3 (show DEFB103A Proteins), and S100A7 (show S100A7 Proteins) production in human keratinocytes and their orthologs in murine imiquimod-treated psoriatic skin.

  5. studied the time course of TLR9 (show TLR9 Proteins) and BD-2gene expression by the corneal epithelial cells in herpetic keratitis in C57Bl/6 and BALB/c mice

  6. mBD-2 was located in cells with dendritic morphology near mediastinal lymph nodes. mBD-2 may play a role in the control of bacilli growth by contributing to establish a Th1 (show HAND1 Proteins) response, being a link between innate and adaptative immunity.

  7. a highly size-specific, TLR4 (show TLR4 Proteins)-dependent, innate defense response to fragmented HA contributes to intestinal epithelium barrier defense through the induction of intracellular HbetaD2 protein.

  8. Murine beta-defensins BD2 and BD3 (show DEFB103A Proteins) together promote resistance against corneal infection by Pseudomonas aeruginosa.

  9. acts directly on immature dendritic cells as an endogenous ligand for Toll-like receptor 4 (show TLR4 Proteins), inducing up-regulation of costimulatory molecules and dendritic cell maturation

  10. The results indicate that BD-2 and -3 may be upregulated during the development of autoimmune sialoadenitis.

Human Defensin, beta 4A (DEFB4) interaction partners

  1. It was concluded that bile acids can differentially regulate colonic epithelial beta-defensin (show DEFB1 Proteins) expression and secretion; the authors discuss the implications for intestinal health and disease.-

  2. Plasma samples of multiple traumatized patients showed high expression of HBD-2, which may protect the severely injured patient from overwhelming bacterial infection.

  3. Giardia co-infection promotes the secretion of antimicrobial peptides beta-defensin 2 and trefoil factor 3 (show TFF3 Proteins) and attenuates attaching and effacing bacteria-induced intestinal disease.(

  4. the effect of adiponectin (show ADIPOQ Proteins) on the unregulated production of hBD2 in UVB-induced premature senescent keratinocytes

  5. these results demonstrate that HNPs1-3 may be potent inhibitors of ADAMTS13 (show ADAMTS13 Proteins) activity, likely by binding to the central A2 domain of VWF (show VWF Proteins) and physically blocking ADAMTS13 (show ADAMTS13 Proteins) binding.

  6. IL-17A (show IL17A Proteins) is a dominant driver of skin pathology in patients with psoriasis, and serum BD-2 is an easily measurable biomarker of psoriasis disease activity that responds rapidly and robustly to IL-17A (show IL17A Proteins) inhibition by secukinumab.

  7. TNF-alpha (show TNF Proteins)- and IL-17A (show IL17A Proteins) mediate synergistic induction of DEFB4 (show DEFB104A Proteins) gene expression in human keratinocytes through IkappaBzeta (show NFKBIZ Proteins)

  8. Study demonstrates high levels of serum hBD2 and LL-37 levels in paediatric post- infectious bronchiolitis obliterans patients. These antimicrobial peptides may have important roles in immune systems and the pathogenesis of these patients.

  9. Finally, Fusobacterium nucleatum FAD-I activation of human BD-2 expression was mediated via both Toll-like receptor-1/2 (TLR-1/2) and TLR-2/6 heterodimerization.

  10. No association was found between DEFB4 (show DEFB104A Proteins)/103A copy number variation and any periodontopathogen level or clinical measure in all samples, Caucasians, or African Americans.

Cow (Bovine) Defensin, beta 4A (DEFB4) interaction partners

  1. The synthetic peptides bovine enteric beta-defensin (EBD (show DEFB1 Proteins)), bovine neutrophil beta-defensin (show DEFB1 Proteins) (BNBD) 9 and BNBD 3 are chemotactic for immature dendritic cells.

Defensin, beta 4A (DEFB4) Protein Profile

Protein Summary

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation.

Gene names and symbols associated with Defensin, beta 4A Proteins (DEFB4)

  • beta-defensin 2 (PBD-2)
  • Gal 4 (GAL4)
  • beta-defensin 2 (THP2)
  • defensin, beta 104 (DEFB104)
  • defensin, beta 4A (DEFB4A)
  • defensin beta 4 (defb4)
  • beta defensin 2 (SBD2)
  • defensin beta 2 (Defb2)
  • neutrophil beta-defensin-9 like peptide (BNBD-9-LIKE)
  • BD-2 protein
  • BD2 protein
  • BNBD-2 protein
  • BNDB-2 protein
  • DEFB-2 protein
  • DEFB2 protein
  • DEFB4 protein
  • DEFB4P protein
  • DEFB102 protein
  • DEFB104 protein
  • DEFB104B protein
  • HBD-2 protein
  • SAP1 protein
  • THP2 protein

Protein level used designations for Defensin, beta 4A Proteins (DEFB4)

beta-defensin 4 , gal-4 , gal-7 , gallinacin 7 , gallinacin-4 , gallinacin-7 , beta-defensin 2 , heterophil prepropeptide 2 , beta-defensin 104A , BD-4 , cBD-4 , DEFB-4 , beta-defensin 104 , beta-defensin 104B , defensin, beta 104 , defensin, beta 104A , beta-defensin 102 , defensin, beta 102 , defensin, beta 4 , beta-defensin 4A , defensin, beta 2 , skin-antimicrobial peptide 1 , BD-2 , rhBD-2 , beta-defensin 4, pseudogene , beta-defensin-2 , defensin, beta 4, pseudogene , Beta-defensin 2

GENE ID SPECIES
404699 Sus scrofa
414342 Gallus gallus
678665 Meleagris gallopavo
735929 Pan troglodytes
100135059 Canis lupus familiaris
100499592 Oncorhynchus mykiss
100505451 Ovis aries
13215 Mus musculus
641631 Rattus norvegicus
1673 Homo sapiens
574144 Macaca mulatta
450193 Pan troglodytes
404063 Bos taurus
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