Defensin beta 4 Proteins (DEFB4)

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Additionally we are shipping Defensin beta 4 Antibodies (28) and Defensin beta 4 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse DEFB4 DEFB4 56519 P82019
DEFB4 64389 O88514
DEFB4 503618 Q8WTQ1
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Top Defensin beta 4 Proteins at antibodies-online.com

Showing 10 out of 22 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated Validation with Western Blot 10 μg Log in to see 12 to 15 Days
$345.35
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 12 to 15 Days
$229.85
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 4 Days
$385.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 6 to 8 Days
$328.21
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$1,991.00
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$1,991.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   1 mg Log in to see 2 to 3 Days
$2,900.00
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 2 to 3 Days
$3,035.21
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   1 mg Log in to see 2 to 3 Days
$2,348.50
Details

DEFB4 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus) ,

Human , ,
,

More Proteins for Defensin beta 4 (DEFB4) Interaction Partners

Mouse (Murine) Defensin beta 4 (DEFB4) interaction partners

  1. The time course of MBD-4 levels in plasma of trauma mice has a similar trend to the HBD-2 levels in plasma of multiple injured patients. MBD-4 expression is induced in liver tissue after multiple trauma.

  2. this investigation revealed an indispensable role for BD3 (show DEFB103A Proteins), BD4, and CRAMP in defense against F. solani-induced keratitis

  3. beta-defensin 4 and 14 contribute to the innate and adaptive immune response in their role as chemoattractants

  4. Data show that recombinant mBD4 (show MBD4 Proteins):Ig and hBD2:Ig fusion proteins retained potent antimicrobial activity against Gram-negative and Gram-positive bacteria, and that these fusion proteins showed specific binding to CCR6 (show CCR6 Proteins)-expressing cells.

  5. Mycobacterial infection induces the expression of mBD3 (show MBD3 Proteins) and mBD4 (show MBD4 Proteins), and both might participate in the control of mycobacterial growth.

Human Defensin beta 4 (DEFB4) interaction partners

  1. It was concluded that bile acids can differentially regulate colonic epithelial beta-defensin (show DEFB1 Proteins) expression and secretion; the authors discuss the implications for intestinal health and disease.-

  2. Plasma samples of multiple traumatized patients showed high expression of HBD-2, which may protect the severely injured patient from overwhelming bacterial infection.

  3. Giardia co-infection promotes the secretion of antimicrobial peptides beta-defensin 2 and trefoil factor 3 (show TFF3 Proteins) and attenuates attaching and effacing bacteria-induced intestinal disease.(

  4. the effect of adiponectin (show ADIPOQ Proteins) on the unregulated production of hBD2 in UVB-induced premature senescent keratinocytes

  5. these results demonstrate that HNPs1-3 may be potent inhibitors of ADAMTS13 (show ADAMTS13 Proteins) activity, likely by binding to the central A2 domain of VWF (show VWF Proteins) and physically blocking ADAMTS13 (show ADAMTS13 Proteins) binding.

  6. IL-17A (show IL17A Proteins) is a dominant driver of skin pathology in patients with psoriasis, and serum BD-2 is an easily measurable biomarker of psoriasis disease activity that responds rapidly and robustly to IL-17A (show IL17A Proteins) inhibition by secukinumab.

  7. TNF-alpha (show TNF Proteins)- and IL-17A (show IL17A Proteins) mediate synergistic induction of DEFB4 (show DEFB104A Proteins) gene expression in human keratinocytes through IkappaBzeta (show NFKBIZ Proteins)

  8. Study demonstrates high levels of serum hBD2 and LL-37 levels in paediatric post- infectious bronchiolitis obliterans patients. These antimicrobial peptides may have important roles in immune systems and the pathogenesis of these patients.

  9. Finally, Fusobacterium nucleatum FAD-I activation of human BD-2 expression was mediated via both Toll-like receptor-1/2 (TLR-1/2) and TLR-2/6 heterodimerization.

  10. No association was found between DEFB4 (show DEFB104A Proteins)/103A copy number variation and any periodontopathogen level or clinical measure in all samples, Caucasians, or African Americans.

Cow (Bovine) Defensin beta 4 (DEFB4) interaction partners

  1. Bovine DEFB4 mRNA is upregulated by lipopolysaccharide in bovine neutrophils and mammary epithelial cells and by 1,25-dihydroxyvitamin D3 in bovine monocytes and mammary epithelial cells.

  2. Recombinant mature bovine neutrophil beta-defensin 4 inhibits mycobacterial growth and controls intracellular survival of mycobacteria.

  3. Stimulation of umbilical-vein endothelial cells with S. aureus or LPS (show IRF6 Proteins) induced the expression of bovine neutrophil beta-defensin 4. This expression was regulated by the autocrine production of tumor necrosis factor-alpha (show TNF Proteins).

  4. The isolation of polymorphisms of BNBD-4 and milk production and somatic cell count are reported.

Defensin beta 4 (DEFB4) Protein Profile

Protein Summary

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation.

Gene names and symbols associated with Defensin beta 4 Proteins (DEFB4)

  • defensin beta 4 (Defb4)
  • defensin, beta 104B (DEFB104B)
  • defensin, beta 4A (DEFB4A)
  • 2310001F05Rik protein
  • BD-2 protein
  • BD-4 protein
  • BNBD-4 protein
  • BNBD4 protein
  • DEFB-2 protein
  • DEFB-4 protein
  • DEFB2 protein
  • Defb3 protein
  • DEFB4 protein
  • DEFB102 protein
  • HBD-2 protein
  • hBD-4 protein
  • SAP1 protein

Protein level used designations for Defensin beta 4 Proteins (DEFB4)

beta-defensin 4 , BD-2 , BD-4 , RBD-2 , RBD-4 , beta defensin-2 , defensin beta 3 , beta-defensin 104 , defensin, beta 104 , beta-defensin 4A , defensin, beta 2 , defensin, beta 4 , skin-antimicrobial peptide 1 , BNDB-4 , neutrophil beta-defensin 4

GENE ID SPECIES
56519 Mus musculus
64389 Rattus norvegicus
503618 Homo sapiens
1673 Homo sapiens
286836 Bos taurus
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