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Degenerative Spermatocyte Homolog 2, Lipid Desaturase (Drosophila) Proteins (DEGS2)

DEGS2 encodes a bifunctional enzyme that is involved in the biosynthesis of phytosphingolipids in human skin and in other phytosphingolipid-containing tissues. Additionally we are shipping Degenerative Spermatocyte Homolog 2, Lipid Desaturase (Drosophila) Antibodies (24) and Degenerative Spermatocyte Homolog 2, Lipid Desaturase (Drosophila) Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DEGS2 70059 Q8R2F2
DEGS2 123099 Q6QHC5
Rat DEGS2 DEGS2 314438 Q564G3
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Top Degenerative Spermatocyte Homolog 2, Lipid Desaturase (Drosophila) Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

DEGS2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Degenerative Spermatocyte Homolog 2, Lipid Desaturase (Drosophila) (DEGS2) Interaction Partners

Mouse (Murine) Degenerative Spermatocyte Homolog 2, Lipid Desaturase (Drosophila) (DEGS2) interaction partners

  1. overexpression of DEGS1 or DEGS2 attenuates the DHC accumulation and increased cell proliferation during hypoxia

  2. DES2 is the dihydroceramide C-4 hydroxylase responsible for the biosynthesis of enriched phytosphingoglycolipids in the microvillous membranes of intestinal epithelial cells

  3. the hydroxylation of dihydroceramide: sphinganine C-4 requires complex formation between Des2 and mb5 via their membrane-spanning domains and electron transfer from NADH to the substrate via the reduction of mb5 by b5R (show CYB5R3 Proteins)

Human Degenerative Spermatocyte Homolog 2, Lipid Desaturase (Drosophila) (DEGS2) interaction partners

  1. Findings demonstrate that a SNP showing genome-wide association study significant association with cognition in schizophrenia is also associated with regulation of DEGS2 expression, implicating a molecular mechanism for the clinical association.

  2. overexpression of DEGS1 or DEGS2 attenuates the DHC accumulation and increased cell proliferation during hypoxia

  3. DES2 was identified and its up-regulation followed during keratinocyte differentiation.

Degenerative Spermatocyte Homolog 2, Lipid Desaturase (Drosophila) (DEGS2) Protein Profile

Protein Summary

This gene encodes a bifunctional enzyme that is involved in the biosynthesis of phytosphingolipids in human skin and in other phytosphingolipid-containing tissues. This enzyme can act as a sphingolipid delta(4)-desaturase, and also as a sphingolipid C4-hydroxylase.

Gene names and symbols associated with DEGS2

  • degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase (Degs2)
  • degenerative spermatocyte homolog 2, lipid desaturase (Drosophila) (DEGS2)
  • delta(4)-desaturase, sphingolipid 2 (DEGS2)
  • delta(4)-desaturase, sphingolipid 2 (Degs2)
  • 2210008A03Rik protein
  • AI852933 protein
  • C14orf66 protein
  • DES2 protein
  • FADS8 protein
  • RGD1305023 protein

Protein level used designations for DEGS2

sphingolipid delta 4 desaturase/C-4 hydroxylase , sphingolipid delta(4)-desaturase/C4-hydroxylase DES2 , degenerative spermatocyte homolog 2, lipid desaturase , sphingolipid C4-hydroxylase/delta 4-desaturase , sphingolipid delta(4)-desaturase 2

GENE ID SPECIES
70059 Mus musculus
540994 Bos taurus
123099 Homo sapiens
314438 Rattus norvegicus
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