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The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). Additionally we are shipping and many more products for this protein.
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Human Polyclonal DHTKD1 Primary Antibody for WB - ABIN527563
Xu, Zhu, Gu, Luo, Ding, Yao, Chen, Wang: DHTKD1 is essential for mitochondrial biogenesis and function maintenance. in FEBS letters 2013
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Human Polyclonal DHTKD1 Primary Antibody for EIA, WB - ABIN951908
Wang, Yoon, Oh, Jeon, Kim, Kim, Byun, Yang, Kim, Kim, Yeom, Yoo, Kim, Kim: Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. in Biochemical and biophysical research communications 2006
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DHTKD1 encodes the E1 subunit of the alpha-ketoadipic acid dehydrogenase complex
DHTKD1 contributes to mitochondrial biogenesis and function maintenance.
DHTKD1 mutations cause 2-aminoadipic and 2-oxoadipic aciduria.
A nonsense mutation in DHTKD1 causes Charcot-Marie-Tooth disease type 2 in a large Chinese pedigree.
In the BXD mouse population, natural variants in Dhtkd1 lead to changes in metabolite levels of 2-aminoadipate and in turn are associated with diabetes status, independently of chow or high fat diet feeding.
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
dehydrogenase E1 and transketolase domain-containing protein 1
, probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial