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Dehydrogenase/reductase (SDR Family) Member 4 Proteins (DHRS4)

Reduces all-trans-retinal and 9-cis retinal. Additionally we are shipping Dehydrogenase/reductase (SDR Family) Member 4 Antibodies (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DHRS4 10901 Q9BTZ2
DHRS4 28200 Q99LB2
DHRS4 266686 Q8VID1
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Top Dehydrogenase/reductase (SDR Family) Member 4 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 10 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,673.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,731.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,731.67
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,731.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 3 to 4 Days
$382.86
Details

DHRS4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced Dehydrogenase/reductase (SDR Family) Member 4 Proteins

  1. Human DHRS4 Protein expressed in Escherichia coli (E. coli) - ABIN667627 : Du, Huang, Liu, Wang, Xu, Wang, Zhu: CDNA cloning of a short isoform of human liver NADP (H) -dependent retinol dehydrogenase/reductase and analysis of its characteristics. in Yi chuan xue bao = Acta genetica Sinica 2004 (PubMed)
    Show all 2 references for ABIN667627

More Proteins for Dehydrogenase/reductase (SDR Family) Member 4 (DHRS4) Interaction Partners

Chimpanzee Dehydrogenase/reductase (SDR Family) Member 4 (DHRS4) interaction partners

  1. Pan troglodytes DH (show DHRS2 Proteins)RS4 gene is ortholog of human DHRS4 gene. These two genes have identical splicing phases, exon-intron structure and their coded proteins have identical catalytic amino-acid residues, Rossman fold consens (show DHRS2 Proteins)us, Peroxisomal Targeting Signal consensus and the three amino-acid residues typical of vertebrate DHRS4 enzymes.

Rhesus Monkey Dehydrogenase/reductase (SDR Family) Member 4 (DHRS4) interaction partners

  1. M. mulatta DHRS2 a (show DHRS2 Proteins)nd DHRS4 genes are syntenic outparalogs that originated from a duplication of the DHRS4 gene that took place before the formation of the mammalian clade. M. mulatta genes are orthologs of human DHRS2 and (show DHRS2 Proteins) DHRS4 genes respectively.

Orang-Utan Dehydrogenase/reductase (SDR Family) Member 4 (DHRS4) interaction partners

  1. P. pygmaeus DHRS2 (show DHRS2 Proteins)and DHRS4 genes are syntenic outparalogs originated from a duplication of the DHRS4 gene that took place before the formation of the mammalian clade. P. pygmaeus genes are orthologs of human DHRS2 and DH (show DHRS2 Proteins)RS4 genes respectively.

Human Dehydrogenase/reductase (SDR Family) Member 4 (DHRS4) interaction partners

  1. NRDRB1, an alternatively spliced isoform of NRDR in vivo functions better than NRDR as a dicarbonyl reductase for xenobiotics containing reactive carbonyls.

  2. Results suggest a novel mechanism of cold inactivation and role of the inducible human DHRS4 in 3beta-hydroxysteroid synthesis and xenobiotic carbonyl metabolism

  3. A rapid evolution (show DHRS2 Proteins)rate brought the human DHRS2 gene, duplicated form of the DHRS4 one, to code a SDR enzyme having subcellular localization, synthesis regulation and specialized cellular functions very different from thos (show DHRS2 Proteins)e of the human DHRS4 enzyme.

  4. This study demonstrates that AS1DHRS4, as a long noncoding RNA, simultaneously controls the chromatin state of each gene within the DHRS4 gene cluster in a discriminative manner.

  5. Analysis of exon composition in the transcripts of DHRS4 gene cluster revealed that exon 1 was absent in all the transcripts initiated from exon a1 of DHRS4L2 and exon a2 of DHRS4L1.

  6. Alternatively spliced variant of NADP(H)-dependent retinol dehydrogenase (show ADH7 Proteins)/reductase with deletion of exon 3 is associated with cervical squamous carcinoma

  7. Novel alternative splicing variants, transcribed from an alternative transcrioption start sites within the DHRS4 gene cluster were identified in this study.

Mouse (Murine) Dehydrogenase/reductase (SDR Family) Member 4 (DHRS4) interaction partners

  1. M. musculus DHRS2 (show DHRS2 Proteins)and DHRS4 genes are syntenic outparalogs that originated from a duplication of the DHRS4 gene that took place before the formation of the mammalian clade. M. musculus genes are orthologs of human DHRS2 a (show DHRS2 Proteins)nd DHRS4 genes respectively.

Cow (Bovine) Dehydrogenase/reductase (SDR Family) Member 4 (DHRS4) interaction partners

  1. Bos taurus DHRS4 g (show DHRS2 Proteins)ene is the ortholog of human DHRS4. These two genes have identical splicing phases, exon-intron structure and their coded proteins have 81.0% sequence identity, identical catalytic amino-acid residues, 2 (show DHRS2 Proteins)7 amino-acid residues interacting with NADP coenzyme, the three amino-acid residues typical of vertebrate DHRS4 enzymes and Rossman fold consensus, and similar Peroxisomal Targeting Signal consensus.

Pig (Porcine) Dehydrogenase/reductase (SDR Family) Member 4 (DHRS4) interaction partners

  1. Sus scrofa DHRS4 g (show DHRS2 Proteins)ene is ortholog of human DHRS4 gene. These two genes have identical splicing phases, exon-intron structure and their coded proteins have identical catalytic amino-acid residues, Rossman fold consensus, P (show DHRS2 Proteins)eroxisomal Targeting Signal consensus and the three amino-acid residues typical of vertebrate DHRS4 enzymes

  2. Peroxisomal localization of tetrameric carbonyl reductase (show CBR2 Proteins).

Rabbit Dehydrogenase/reductase (SDR Family) Member 4 (DHRS4) interaction partners

  1. O. cuniculus DHRS2 (show DHRS2 Proteins) and DHRS4 genes are syntenic outparalogs that originated from a duplication of the DHRS4 gene that took place before the formation of the mammalian clade. O. cuniculus genes are orthologs of human DHRS2 (show DHRS2 Proteins) and DHRS4 genes respectively

Dehydrogenase/reductase (SDR Family) Member 4 (DHRS4) Protein Profile

Protein Summary

Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co- factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones (By similarity).

Gene names and symbols associated with DHRS4

  • dehydrogenase/reductase (SDR family) member 4 (DHRS4)
  • dehydrogenase/reductase (SDR family) member 4 (dhrs4)
  • dehydrogenase/reductase (SDR family) member 4 (Dhrs4)
  • AI043103 protein
  • AI790593 protein
  • CR protein
  • D14Ucla2 protein
  • mouNRDR protein
  • NDRD protein
  • NRDR protein
  • PHCR protein
  • PSCD protein
  • rabNRDR protein
  • RRD protein
  • SCAD-SRL protein
  • SDR-SRL protein
  • SDR25C1 protein
  • SDR25C2 protein

Protein level used designations for DHRS4

dehydrogenase/reductase SDR family member 4 , dehydrogenase/reductase (SDR family) member 4 , CR , NDRD , PHCR , peroxisomal short-chain alcohol dehydrogenase , NADPH-dependent retinol dehydrogenase/reductase , NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase , NADP-dependent retinol dehydrogenase , dehydrogenase/reductase (SDR family) member 4 like 2A , short chain dehydrogenase/reductase family 25C, member 1 , short chain dehydrogenase/reductase family 25C, member 2 , short-chain dehydrogenase/reductase family member 4 , DCR-AKL , NADP-retinol dehydrogenase , carbonyl reductase , carbonyl reductase/NADP-retinol dehydrogenase , NADH-dependent retinal reductase

GENE ID SPECIES
480254 Canis lupus familiaris
444771 Xenopus laevis
452804 Pan troglodytes
548501 Xenopus (Silurana) tropicalis
714613 Macaca mulatta
100172190 Pongo abelii
10901 Homo sapiens
28200 Mus musculus
266686 Rattus norvegicus
281360 Bos taurus
397082 Sus scrofa
100009020 Oryctolagus cuniculus
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