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DIO2 Proteins

(Deiodinase, Iodothyronine, Type II (DIO2))
The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
DIO2 Protein (AA 166-265) (GST tag) DIO2 Protein (AA 166-265) (GST tag) DIO2 Protein (AA 166-265) (GST tag) (ABIN1351608)

DIO2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

DIO2 Protein (AA 1-273) (rho-1D4 tag) DIO2 Protein (AA 1-273) (rho-1D4 tag) DIO2 Protein (AA 1-273) (rho-1D4 tag) (ABIN3104665)

Crystallography grade DIO2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

DIO2 Protein (AA 1-266) (rho-1D4 tag) DIO2 Protein (AA 1-266) (rho-1D4 tag) DIO2 Protein (AA 1-266) (rho-1D4 tag) (ABIN3120328)

Crystallography grade DIO2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

DIO2 Proteins by Grade

Find DIO2 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

DIO2 Proteins by Origin

Find DIO2 Proteins for a variety of species such as anti-Human DIO2, anti-Rat DIO2, anti-Mouse DIO2. The species listed below are among those available. Click on a link to go to the corresponding products.

DIO2 Proteins by Source

Here you will find DIO2 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

DIO2 Proteins by Protein Type

Here you can find DIO2 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

DIO2 Proteins by Application

Find DIO2 Proteins validated for a specific application such as SDS, WB, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular DIO2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351608
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3104665
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3120328
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413544
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413547
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7396928
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7424398
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
  • (1)
Cat. No. ABIN5713964
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3009143
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6120545
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6378957
Quantity 1 mg
Datasheet Datasheet
Reactivity Bullfrog
Source Yeast
Validations
Cat. No. ABIN1664560
Quantity 1 mg
Datasheet Datasheet
Reactivity Neoceratodus forsteri
Source Yeast
Validations
Cat. No. ABIN1639197
Quantity 1 mg
Datasheet Datasheet
Reactivity Chicken
Source Yeast
Validations
Cat. No. ABIN1653539
Quantity 1 mg
Datasheet Datasheet

Aliases for DIO2 Proteins

iodothyronine deiodinase 2 (DIO2) Proteins
deiodinase, iodothyronine, type II (Dio2) Proteins
iodothyronine deiodinase 2 (dio2) Proteins
deiodinase, iodothyronine, type II (dio2) Proteins
deiodinase, iodothyronine, type 2 L homeolog (dio2.L) Proteins
deiodinase, iodothyronine, type 2 (dio2) Proteins
iodothyronine deiodinase 2 (Dio2) Proteins
type II iodothyronine deiodinase (LOC100861220) Proteins
5DII Proteins
5dii Proteins
AI324267 Proteins
cb684 Proteins
D2 Proteins
Deio2 Proteins
DIO2 Proteins
dio2-A Proteins
DIOII Proteins
SelY Proteins
sely Proteins
TXDI2 Proteins
txdi2 Proteins
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