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Deleted in Lung and Esophageal Cancer 1 (DLEC1) ELISA Kits

DLEC1 contains 37 exons, spans approximately 59-kb, and is located in the 3p22-p21.3 chromosomal segment that is commonly deleted in various carcinomas. Additionally we are shipping DLEC1 Antibodies (49) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human DLEC1 DLEC1 9940 Q9Y238
Anti-Mouse DLEC1 DLEC1 320256  
Anti-Rat DLEC1 DLEC1 501070  
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More ELISA Kits for DLEC1 Interaction Partners

Human Deleted in Lung and Esophageal Cancer 1 (DLEC1) interaction partners

  1. DLEC1 mediates tumor-suppressive activities through NF-kappaB (show NFKB1 ELISA Kits) signaling.

  2. DLEC1 methylation was not associated with the clinicopathological variables of gastric cancer.

  3. DLEC1 is down-regulated in head and neck squamous cell tumors and it's promoter methylation is not associated with the clinicopathological parameters.

  4. methylation-mediated silencing of DLEC1 plays an important role in multiple lymphomagenesis, and may serve as a non-invasive tumor marker for lymphoma diagnosis

  5. Repression of DLEC1 in squamous cell carcinoma tissues is associated with promoter hypermethylation. DLEC1 is downregulated in sinonasal squamous cell carcinoma and inverted papilloma and has a distinct mechanism.

  6. Epigenetic inactivation of DLEC1 was crucial in gastric and colorectal carcinogenesis. DLEC1 methylation in serum may be a promise biomarker for GAC (show GLS ELISA Kits) and CRAC early diagnosis.

  7. results demonstrate that down-expression and promoter methylation of DLEC1 increased from normal tissues to premalignancies and then to malignancies.

  8. Frequent epigenetic inactivation of deleted in lung and esophageal cancer 1 gene by promoter methylation is associated with non-small-cell lung cancer.

  9. DLEC1 is often down-regulated by CpG methylation and shows tumor inhibitory function in renal cell carcinoma cells, indicating its role as a tumor suppressor

  10. DLEC1 expression levels were significantly lower in samples from patients who developed metastasis, local recurrence, or died of breast cancer when compared to those who were disease free for >10 years.

DLEC1 Antigen Profile

Antigen Summary

This gene contains 37 exons, spans approximately 59-kb, and is located in the 3p22-p21.3 chromosomal segment that is commonly deleted in various carcinomas. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins. Aberrant transcription of this gene may be involved in carcinogenesis of the lung, esophagus, and kidney.

Gene names and symbols associated with DLEC1

  • deleted in lung and esophageal cancer 1 (DLEC1) antibody
  • deleted in lung and esophageal cancer 1 (dlec1) antibody
  • deleted in lung and esophageal cancer 1 (Dlec1) antibody
  • D630005C06Rik antibody
  • DLC1 antibody
  • F56 antibody

Protein level used designations for DLEC1

deleted in lung and esophageal cancer 1 , deleted in lung and esophageal cancer protein 1-like , DLC-1 , deleted in lung and esophageal cancer 1 transcript varient 2 , deleted in lung and esophageal cancer protein 1 , deleted in lung and esophageal cancer protein 1 homolog , deleted in lung and esophageal cancer 1 isoform DLEC1-N1

GENE ID SPECIES
420418 Gallus gallus
618746 Bos taurus
697163 Macaca mulatta
100021635 Monodelphis domestica
100054035 Equus caballus
100153766 Sus scrofa
100187070 Ciona intestinalis
100462075 Pongo abelii
100479554 Ailuropoda melanoleuca
470790 Pan troglodytes
100542378 Meleagris gallopavo
9940 Homo sapiens
320256 Mus musculus
501070 Rattus norvegicus
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