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Deoxyguanosine Kinase Proteins (DGUOK)

In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. Additionally we are shipping Deoxyguanosine Kinase Antibodies (56) and Deoxyguanosine Kinase Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DGUOK 1716 Q16854
DGUOK 27369 Q9QX60
Rat DGUOK DGUOK 297389  
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Top Deoxyguanosine Kinase Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

DGUOK Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Deoxyguanosine Kinase (DGUOK) Interaction Partners

Human Deoxyguanosine Kinase (DGUOK) interaction partners

  1. sequencing results showed that the patient was a compound heterozygote for c.679G>A and c.817delT in the DGUOK gene

  2. thymidine kinase (show TK1 Proteins) 2 but not deoxyguanosine kinase is up-regulated during the stationary growth phase of cultured cells

  3. study expands the spectrum of disorders caused by mutations in DGUOK.

  4. Deoxyguanosine kinase gene mutations combined with impaired glucose homeostasis and iron overload features are associated with severe progressive liver failure.

  5. c.592-4_c.592-3delTT mutation causes exon skipping and is and responsible for the DGUOK deficiency

  6. Neurological symptoms appeared later and were mild, in agreement with the limited brain pathology. Molecular analysis of the dGK (show DGKB Proteins) gene should be performed in infants with cirrhosis even in the absence of CNS involvement.

  7. Low level of mitochondrial deoxyguanosine kinase is the dominant factor in acquired resistance to 9-beta-D-arabinofuranosylguanine cytotoxicity

  8. A novel mutation in the deoxyguanosine kinase gene causing depletion of mitochondrial DNA. Homozygous nonsense mutation in exon 3 of DGUOK (313C-->T).

  9. Data show that inorganic tripolyphosphate (PPP(i)) is a good donor for human ceoxycytidine kinase and deoxyguanosine kinase.

  10. deoxycytidine kinase (show DCK Proteins), deoxyguanosine kinase, and cytosolic 5'-nucleotidase (show NT5E Proteins) I are regulated in a cell cycle-dependent manner in MOLT-4 cells

Mouse (Murine) Deoxyguanosine Kinase (DGUOK) interaction partners

  1. thymidine kinase (show TK1 Proteins) 2 but not deoxyguanosine kinase is up-regulated during the stationary growth phase of cultured cells

Deoxyguanosine Kinase (DGUOK) Protein Profile

Protein Summary

In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.

Gene names and symbols associated with Deoxyguanosine Kinase Proteins (DGUOK)

  • deoxyguanosine kinase (DGUOK)
  • deoxyguanosine kinase (dguok)
  • deoxyguanosine kinase (dgk)
  • deoxyguanosine kinase (Ccan_04750)
  • deoxyguanosine kinase (Dguok)
  • DDBDRAFT_0218264 protein
  • DDBDRAFT_0233982 protein
  • DDB_0218264 protein
  • DDB_0233982 protein
  • dGK protein
  • dGK1 protein
  • dGK2 protein
  • dGK3 protein
  • DGUOK protein
  • MTDPS3 protein
  • zgc:86625 protein

Protein level used designations for Deoxyguanosine Kinase Proteins (DGUOK)

deoxyguanosine kinase , deoxyguanosine kinase, mitochondrial

GENE ID SPECIES
707554 Macaca mulatta
509834 Bos taurus
475791 Canis lupus familiaris
459328 Pan troglodytes
100005067 Danio rerio
444017 Xenopus laevis
8621793 Dictyostelium discoideum AX4
10979429 Capnocytophaga canimorsus Cc5
1716 Homo sapiens
27369 Mus musculus
297389 Rattus norvegicus
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