Deoxyribonuclease II, Lysosomal (DNASE2) ELISA Kits

The protein encoded by DNASE2 shares considerable sequence similarity to, and is structurally related to DNase II. Additionally we are shipping Deoxyribonuclease II, Lysosomal Antibodies (53) and Deoxyribonuclease II, Lysosomal Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse DNASE2 DNASE2 13423 P56542
Anti-Human DNASE2 DNASE2 1777 O00115
Anti-Rat DNASE2 DNASE2 171575 Q9QZK8
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More ELISA Kits for Deoxyribonuclease II, Lysosomal Interaction Partners

Fruit Fly (Drosophila melanogaster) Deoxyribonuclease II, Lysosomal (DNASE2) interaction partners

  1. These results confirm that DNase II and the ability to clear macromolecular DNA is essential for maintaining proper immune function in Drosophila.

  2. findings indicate that DNaseII can act cell autonomously to degrade DNA during nonapoptotic cell death.

Mouse (Murine) Deoxyribonuclease II, Lysosomal (DNASE2) interaction partners

  1. holocrine secretion is a DNase2-mediated form of programmed cell death and suggest that autophagy-dependent metabolism, DNA degradation

  2. Data show that Klf1 (show KLF1 ELISA Kits) is expressed in central macrophagse of erythroblastic islands and that it binds and activates the promoter of Dnase2a.

Human Deoxyribonuclease II, Lysosomal (DNASE2) interaction partners

  1. Single nucleotide polymorphisms producing a loss-of-function variant of the enzymes in DNASE1 (show DNASE1 ELISA Kits), DNASE1L3 (show DNASE1L3 ELISA Kits), and DNASE2, possibly serving as a genetic risk factor for autoimmune diseases, were confirmed.

  2. 15 nonsynonymous human DNase II SNPs were genotyped in three ethnic groups including 16 different populations using the PCR-restriction fragment length polymorphism technique.

  3. study demonstrated the relationship of genotypes/haplotypes with the in vivo DNase II and promoter activities; significant correlations between genotype in each rheumatoid arthritis (RA)-related SNP and enzymatic activity levels were found; alleles associated with RA exhibited a reduction in serum DNase II activity.

  4. upregulation of expression during myelomonocytic differentiation of HL-60 and THP-1 (show GLI2 ELISA Kits) cells

  5. Sp1 (show PSG1 ELISA Kits) and Sp3 (show SP3 ELISA Kits) are involved in up-regulation of this enzyme's transcriptoin during cell differentiation of hl-60 cells.

  6. the enzyme is a monomeric phospholipase D (show PLD ELISA Kits)-family member with a pseudodimeric protein fold

  7. The association of SNPs in the 5'-regulatory region of the DNA degrading enzyme DNASE2 with Rheumatoid Arthritis implies a role for this enzyme in the pathogenesis of this autoimmune disease.

Pig (Porcine) Deoxyribonuclease II, Lysosomal (DNASE2) interaction partners

  1. Proteolytic processing of porcine deoxyribonuclease II occurs in lysosomes but is not required for enzyme activation

  2. Data showed an association between PARP-1 and LEI/L-DNase II.

Deoxyribonuclease II, Lysosomal (DNASE2) Antigen Profile

Antigen Summary

This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.

Gene names and symbols associated with DNASE2

  • Deoxyribonuclease II (DNaseII) antibody
  • deoxyribonuclease II, lysosomal L homeolog (dnase2.L) antibody
  • deoxyribonuclease 2, lysosomal (DNASE2) antibody
  • deoxyribonuclease II, lysosomal (dnase2) antibody
  • deoxyribonuclease II (dnase2) antibody
  • deoxyribonuclease II alpha (Dnase2a) antibody
  • deoxyribonuclease 2, lysosomal (Dnase2) antibody
  • CG7780 antibody
  • DDBDRAFT_0188966 antibody
  • DDBDRAFT_0252883 antibody
  • DDB_0188966 antibody
  • DDB_0252883 antibody
  • dDNase II antibody
  • Dmel\\CG7780 antibody
  • DNase antibody
  • DNase-1 antibody
  • DNase1 antibody
  • DNase 1 antibody
  • Dnase2 antibody
  • Dnase2a antibody
  • DNL antibody
  • DNL2 antibody
  • fa92d01 antibody
  • LOC733868 antibody
  • MGC80103 antibody
  • wu:fa56d08 antibody
  • wu:fa92d01 antibody

Protein level used designations for DNASE2

deoxyribonuclease II , CG7780-PA , DNaseII-PA , acid DNase , deoxyribonuclease 1 , deoxyribonuclease II, lysosomal , deoxyribonuclease-2-alpha , fa56d08 , DNase II alpha , lysosomal DNase II , DNase II, lysosomal , R31240_2 , deoxyribonuclease II alpha

48228 Drosophila melanogaster
446506 Xenopus laevis
476697 Canis lupus familiaris
733868 Xenopus (Silurana) tropicalis
747576 Pan troglodytes
100000399 Danio rerio
100171654 Pongo abelii
100599185 Nomascus leucogenys
8627734 Dictyostelium discoideum AX4
13423 Mus musculus
1777 Homo sapiens
171575 Rattus norvegicus
282218 Bos taurus
397398 Sus scrofa
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