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Desmocollin 2 Proteins (DSC2)

The protein encoded by DSC2 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. Additionally we are shipping Desmocollin 2 Antibodies (44) and Desmocollin 2 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DSC2 1824 Q02487
DSC2 13506 P55292
DSC2 291760  
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Top Desmocollin 2 Proteins at antibodies-online.com

Showing 8 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Rat His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

DSC2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

Top referenced Desmocollin 2 Proteins

  1. Human Desmocollin 2 Protein expressed in Human Cells - ABIN2003427 : Liu, Qian, Gritsenko, Camp, Monroe, Moore, Smith: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. in Journal of proteome research 2005 (PubMed)
    Show all 3 references for ABIN2003427

  2. Rat (Rattus) Desmocollin 2 Protein expressed in Human Cells - ABIN2009399 : Ramachandran, Boontheung, Xie, Sondej, Wong, Loo: Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. in Journal of proteome research 2006 (PubMed)
    Show all 3 references for ABIN2009399

More Proteins for Desmocollin 2 (DSC2) Interaction Partners

Human Desmocollin 2 (DSC2) interaction partners

  1. Data suggest juxtamembrane regions/domains of desmocollin-2 (DSC2), plakophilin 2 (PKP2), and plakophilin 3 (PKP3 (show PKP3 Proteins)) are involved in desmosome formation in epithelial cells; DSC2 participates in desmosome formation in absence of desmoglein 2 (DSG2 (show DSG2 Proteins)).

  2. Oxidized low-density lipoprotein attenuated desmoglein 1 (show DSG1 Proteins) and desmocollin 2 expression in human umbilical vein endothelial cells.

  3. DSC2 promoter methylation is associated with Breast Cancer.

  4. Homozygous founder mutation in DSC2 gene identified among Italian arrhythmogenic cardiomyopathy probands, providing evidence of the occurrence of recessive DSC2 mutations presenting with biventricular forms of the disease.

  5. Desmocollin-2 mutations are described for dilated cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy, as well. Desmocollin-2 mutation was described in a case of arrhythmogenic biventricular cardiomyopathy

  6. a novel Nrf2 (show GABPA Proteins)-miR (show MLXIP Proteins)-29-Dsc2 axis controls desmosome function and cutaneous homeostasis

  7. ECG reliably identifies homozygous p.Gln554X desmocollin-2 carriers and may be useful as an initial step in the screening of high-risk Hutterites.

  8. DSC2 may be involved in the regulation of the invasive behavior of cells by a mechanism that controls cellcell attachment and cytoskeleton rearrangement

  9. Data demonstrate that partner desmosomal cadherins Dsg2 (show DSG2 Proteins) and Dsc2 play opposing roles in controlling colonic carcinoma cell proliferation through differential effects on EGFR (show EGFR Proteins) signaling.

  10. Low expression of DSC 1 (show RCAN1 Proteins), 2, and 3 was observed in 55, 54, and 79 % of liver metastases.

Mouse (Murine) Desmocollin 2 (DSC2) interaction partners

  1. Data demonstrate that partner desmosomal cadherins Dsg2 (show DSG2 Proteins) and Dsc2 play opposing roles in controlling colonic carcinoma cell proliferation through differential effects on EGFR (show EGFR Proteins) signaling.

  2. plakoglobin (show JUP Proteins) (Pg) in conjunction with lymphoid enhancer-binding factor 1 (Lef-1 (show LEF1 Proteins)) differentially regulates the proximal promoters of Dsc2 and Dsc3 (show DSC3 Proteins)

Desmocollin 2 (DSC2) Protein Profile

Protein Summary

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms.

Gene names and symbols associated with Desmocollin 2 Proteins (DSC2)

  • desmocollin 2 (DSC2)
  • desmocollin 2 (Dsc2)
  • ARVD11 protein
  • AW228162 protein
  • CDHF2 protein
  • DG2 protein
  • DGII/III protein
  • DSC2 protein
  • Dsc2a protein
  • Dsc2b protein
  • DSC3 protein

Protein level used designations for Desmocollin 2 Proteins (DSC2)

desmocollin type 2 , desmocollin 2 , desmocollin 3 , desmocollin-3-like , desmocollin-2-like , cadherin family member 2 , desmocollin-2 , desmosomal glycoprotein II/III , epithelial type 2 desmocollin

GENE ID SPECIES
100065829 Equus caballus
403860 Canis lupus familiaris
428527 Gallus gallus
455352 Pan troglodytes
455353 Pan troglodytes
712805 Macaca mulatta
100412409 Callithrix jacchus
100413004 Callithrix jacchus
100452912 Pongo abelii
100543299 Meleagris gallopavo
100592743 Nomascus leucogenys
1824 Homo sapiens
281128 Bos taurus
13506 Mus musculus
291760 Rattus norvegicus
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