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Desmocollin 3 Proteins (DSC3)

The protein encoded by DSC3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. Additionally we are shipping Desmocollin 3 Antibodies (66) and Desmocollin 3 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DSC3 1825 Q14574
DSC3 13507 P55850
Rat DSC3 DSC3 307563  
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Top Desmocollin 3 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

DSC3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Desmocollin 3 (DSC3) Interaction Partners

Human Desmocollin 3 (DSC3) interaction partners

  1. Suggest that Dsc3 (show DSC2 Proteins) can mediate FSH (show BRD2 Proteins)-induced ovarian cancer cell proliferation by activating the EGFR (show EGFR Proteins)/Akt (show AKT1 Proteins) signaling pathway.

  2. data suggests that DNA methylation (show HELLS Proteins) contributes to down-regulation of DSC3 (show DSC2 Proteins) in prostate cancer, and loss of DSC3 (show DSC2 Proteins) predicts poor clinical outcome.

  3. Low expression of DSC 1 (show RCAN1 Proteins), 2, and 3 was observed in 55, 54, and 79 % of liver metastases.

  4. The data show an important role of physiologically occurring transcript d2-d4 in normal brain function. Interference with this role by DSC3 (show DSC2 Proteins) is a likely pathological mechanism in X-chromosomal dystonia parkinsonism syndrome

  5. High expression of desmocollin 1 (DSC1 (show DSC1 Proteins)) was observed in 41.6%, DSC2 (show DSC2 Proteins) in 58.0%, DSC3 (show DSC2 Proteins) in 61.4%, E-cadherin (show CDH1 Proteins) in 71.4%, CDX2 (show CDX2 Proteins) in 58.0%, PITX1 (show PITX1 Proteins) in 55.0%, CDK4 (show CDK4 Proteins) in 0.2%, TLE1 (show TLE1 Proteins) in 1.3%, Factor H (show CFH Proteins) in 42.5%, and MDM2 (show MDM2 Proteins) in 0.2% of colorectal carcinomas.

  6. The p53 (show TP53 Proteins) target gene desmocollin 3 (show DSC2 Proteins) acts as a novel tumor suppressor through inhibiting EGFR (show EGFR Proteins)/ERK (show EPHB2 Proteins) pathway in human lung cancer.

  7. These findings demonstrate that IgG autoantibodies against an additional component of the desmosomes, Dsc3 (show DSC2 Proteins), induce loss of keratinocyte adhesion and thus may contribute to blister formation in pemphigus.

  8. Methylation status of DSC3 (show DSC2 Proteins) DNA is a prognostic marker for colorectal cancer. P53 (show TP53 Proteins) appears to have an important role in regulating DSC3 (show DSC2 Proteins) expression.

  9. Autoimmunity to DSC3 (show DSC2 Proteins) in Pemphigus vulgaris (show DSG3 Proteins).

  10. Gene-profiling experiments of breast cancer cells infected with wt p53 (show TP53 Proteins) revealed both MASPIN (show SERPINB5 Proteins) and desmocollin 3 (DSC3 (show DSC2 Proteins)) to be p53 (show TP53 Proteins)-target genes, even though both genes are silenced in association with aberrant cytosine methylation of their promoters

Mouse (Murine) Desmocollin 3 (DSC3) interaction partners

  1. plakoglobin (show JUP Proteins) (Pg) in conjunction with lymphoid enhancer-binding factor 1 (Lef-1 (show LEF1 Proteins)) differentially regulates the proximal promoters of Dsc2 (show DSC2 Proteins) and Dsc3

  2. hypothesize that DSC3 can contribute to the progression of tumors both by cell adhesion-dependent (skin surface) and likely by cell adhesion-independent (invading tumor cells) mechanisms

  3. The function of DSC3 in the development and maintenance of stratified epithelia, in particular the epidermis and hair follicles, was investigated.

Desmocollin 3 (DSC3) Protein Profile

Protein Summary

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.

Gene names and symbols associated with Desmocollin 3 Proteins (DSC3)

  • desmocollin 3 (dsc3)
  • desmocollin 3 (LOC100347153)
  • desmocollin 2 (DSC3)
  • desmocollin 3 (DSC3)
  • desmocollin 3 (Dsc3)
  • 5430426I24Rik protein
  • CDHF3 protein
  • DSC protein
  • DSC1 protein
  • DSC2 protein
  • dsc3 protein
  • DSC4 protein
  • HT-CP protein
  • MGC85083 protein

Protein level used designations for Desmocollin 3 Proteins (DSC3)

desmocollin 3 , cadherin family member 3 , desmocollin-3 , desmocollin-4

GENE ID SPECIES
517061 Bos taurus
734252 Xenopus laevis
100135098 Xenopus (Silurana) tropicalis
100347153 Oryctolagus cuniculus
100685374 Canis lupus familiaris
1825 Homo sapiens
281129 Bos taurus
13507 Mus musculus
307563 Rattus norvegicus
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