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Desmoglein 2 (DSG2) ELISA Kits

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Additionally we are shipping Desmoglein 2 Antibodies (114) and Desmoglein 2 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DSG2 1829 Q14126
DSG2 13511 O55111
Anti-Rat DSG2 DSG2 307562  
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Top Desmoglein 2 ELISA Kits at antibodies-online.com

Showing 2 out of 7 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.055 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details
Mouse 0.039 ng/ml 0.156-10 ng/mL   96 Tests Log in to see 11 to 13 Days
$910.56
Details

Top referenced Desmoglein 2 ELISA Kits

  1. Human Desmoglein 2 ELISA Kit for Sandwich ELISA - ABIN417921 : Pillai, Sankoorikal, Johnson, Seneviratne, Zurko, Brown, Hathout, Rose: Directional secretomes reflect polarity-specific functions in an in vitro model of human bronchial epithelium. in American journal of respiratory cell and molecular biology 2014 (PubMed)
    Show all 2 references for ABIN417921

More ELISA Kits for Desmoglein 2 Interaction Partners

Zebrafish Desmoglein 2 (DSG2) interaction partners

Human Desmoglein 2 (DSG2) interaction partners

  1. a novel pathway of CSTA (show CSTA ELISA Kits) regulation involving Dsg2

  2. DSG2 and DSG3 (show DSG3 ELISA Kits) might be potential diagnostic markers for squamous cell carcinoma of the lung.

  3. In endometrial luminal epithelium, cadherin 6 (show CDH6 ELISA Kits), desmoglein 2 and plexin b2 (show PLXNB2 ELISA Kits) were surprisingly found in the apical as well as the lateral membrane domain; their knock-down compromised epithelial integrity.

  4. a low DSG2 expression phenotype is a useful prognostic biomarker of tumor aggressiveness and may serve as an aid in identifying patients with clinically significant prostate cancer.

  5. Six variants of uncertain clinical significance in the PKP2 (show PKP2 ELISA Kits), JUP (show JUP ELISA Kits), and DSG2 genes showed a deleterious effect on mRNA splicing, indicating these are ARVD (show TGFB3 ELISA Kits)/C-related pathogenic splice site mutations.

  6. This structure reveals that the ectodomain of Dsg2 is flexible even in the calcium-bound state and, on average, is shorter than the type 1 cadherin crystal structures.

  7. Data demonstrate that partner desmosomal cadherins Dsg2 and Dsc2 (show DSC2 ELISA Kits) play opposing roles in controlling colonic carcinoma cell proliferation through differential effects on EGFR (show EGFR ELISA Kits) signaling.

  8. Desmoglein 2 expression attenuates migration of melanoma cells, mediated by downregulation of secretogranin II (show SCG2 ELISA Kits).

  9. Reduced cardiac desmoglein-2 and desmocollin-2 (show DSC2 ELISA Kits) levels appear to be specifically associated with Arrhythmogenic right ventricular Dysplasia/cardiomyopathy, independent of underlying mutations.

  10. Gal3 has a role in stabilizing desmoglein-2, a desmosomal cadherin, and intercellular adhesion in intestinal epithelial cells

Mouse (Murine) Desmoglein 2 (DSG2) interaction partners

  1. Data suggest that loss of desmoglein 2 (Dsg2) compromises adhesion, and that this is a major pathogenic mechanism in DSG2-related and probably other desmosome-related arrhythmogenic cardiomyopathy (AC).

  2. Dsg2 modulates Gli1 (show GLI1 ELISA Kits) expression. Dsg2-mediated hyperproliferation, MEK (show MDK ELISA Kits)/Erk1/2 (show MAPK1/3 ELISA Kits) activation, and accelerated squamous tumor development are enhanced on the Ptc1 (show PTCH1 ELISA Kits)+/lacZ (show GLB1 ELISA Kits) background.

  3. a novel pathway of CSTA (show CSTA ELISA Kits) regulation involving Dsg2

  4. Data demonstrate that desmoglein-2 plays a critical role in cardiomyocyte cohesion and function.

  5. Data demonstrate that partner desmosomal cadherins Dsg2 and Dsc2 (show DSC2 ELISA Kits) play opposing roles in controlling colonic carcinoma cell proliferation through differential effects on EGFR (show EGFR ELISA Kits) signaling.

  6. Dsg2 compensates for Dsg3 (show DSG3 ELISA Kits) depletion with regard to cell cohesion, but does not regulate p38 MAPK (show MAPK14 ELISA Kits) signaling.

  7. In vivo interaction between Dsg2 and Na(V)1.5 provides a molecular pathway for the observed electrical disturbances during the early arrhythmogenic right ventricular cardiomyopathy.

  8. Mutant desmoglein 2 cannot support the increased requirements placed on intercalated disc adhesion during postnatal heart development. This induces cardiomyocyte death, aseptic inflammation and fibrotic replacement.

  9. ventricular arrhythmias that has been linked to mutations in desmosomal proteins including desmoglein 2

  10. Myocyte necrosis underlies progressive myocardial dystrophy in N271S-dsg2-related arrhythmogenic right ventricular cardiomyopathy.

Desmoglein 2 (DSG2) Antigen Profile

Antigen Summary

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.

Gene names and symbols associated with Desmoglein 2 (DSG2) ELISA Kits

  • desmoglein 2 (DSG2) antibody
  • desmoglein 2 (dsg2) antibody
  • desmoglein 2 (LOC100348149) antibody
  • desmoglein 2 (Dsg2) antibody
  • AA408168 antibody
  • ARVC10 antibody
  • ARVD10 antibody
  • CDHF5 antibody
  • CMD1BB antibody
  • D18Ertd293e antibody
  • dsc antibody
  • DSG2 antibody
  • dsga antibody
  • HDGC antibody
  • si:dkeyp-51f12.6 antibody
  • wu:fj23f02 antibody

Protein level used designations for Desmoglein 2 (DSG2) ELISA Kits

desmoglein 2 , Dsg alpha , desmocollin a , desmoglein-2-like , HDGC , cadherin family member 5 , desmoglein-2

GENE ID SPECIES
100066038 Equus caballus
428529 Gallus gallus
455356 Pan troglodytes
560026 Danio rerio
705805 Macaca mulatta
100348149 Oryctolagus cuniculus
100456327 Pongo abelii
100565052 Anolis carolinensis
1829 Homo sapiens
13511 Mus musculus
307562 Rattus norvegicus
490500 Canis lupus familiaris
100625833 Sus scrofa
508151 Bos taurus
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