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Desmoglein 4 Proteins (DSG4)

DSG4 encodes a member of the desmoglein subgroup of desmosomal cadherins. Additionally we are shipping Desmoglein 4 Antibodies (24) and Desmoglein 4 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DSG4 147409 Q86SJ6
DSG4 16769 Q7TMD7
DSG4 291754 Q6W3B0
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Top Desmoglein 4 Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,679.50
Details

DSG4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for Desmoglein 4 (DSG4) Interaction Partners

Human Desmoglein 4 (DSG4) interaction partners

  1. This study further extends the body of evidence that mutations in the DSG4 gene result in both hypotrichosis and monilethrix-like scalp hair.

  2. Epitopes of Dsg4 may play a role in the pathogenesis of pemphigus vulgaris (show DSG3 Proteins) .

  3. show that HOXC13, LEF1 (show LEF1 Proteins) and FOXN1 (show FOXN1 Proteins) repress DSG4 transcription and provide in vitro and in vivo evidence correlating the Notch (show NOTCH1 Proteins) pathway with the activation and/or maintenance of DSG4 expression in the hair follicle.

  4. the human desmoglein 4 gene (DSG4) demonstrates that it is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 (show DSG1 Proteins) and DSG3 (show DSG3 Proteins).

  5. The essential role of desmoglein 4 in skin was established by identifying mutations in families with inherited hypotrichosis, as well as in the lanceolate hair mouse. We also show that DSG4 is an autoantigen in pemphigus vulgaris (show DSG3 Proteins).

  6. DSG4 is pathogenic in pemphigus and staphylococcal scalded skin syndrome.

  7. The DSG4 protein is expressed in the more highly differentiated layers of the epidermis.

  8. identification of a single nucleotide deletion within exon 3 of DSG4, designated 87delG in a Pakistani family with localized autosomal recessive hypotrichosis; this results in a frameshift and premature termination codon 162 bp downstream of the deletion

Mouse (Murine) Desmoglein 4 (DSG4) interaction partners

  1. show that HOXC13, LEF1 (show LEF1 Proteins) and FOXN1 (show FOXN2 Proteins) repress DSG4 transcription and provide in vitro and in vivo evidence correlating the Notch (show NOTCH1 Proteins) pathway with the activation and/or maintenance of DSG4 expression in the hair follicle.

  2. Mast cell hyperplasia is associated with Dsg4-deficient hypotrichosis mice.

  3. Smad4 (show SMAD4 Proteins) loss-associated Dsg4 depletion contributed, at least in part, to hair follicles degeneration in Smad4 (show SMAD4 Proteins) deficient skin.

Desmoglein 4 (DSG4) Protein Profile

Protein Summary

This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded protein is a transmembrane component in desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and potentially in other skin disorders. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with Desmoglein 4 Proteins (DSG4)

  • desmoglein 4 (DSG4)
  • desmoglein 4 (Dsg4)
  • CDGF13 protein
  • CDHF13 protein
  • DSG4 protein
  • lah protein

Protein level used designations for Desmoglein 4 Proteins (DSG4)

desmoglein 4 , desmoglein-4-like , CDH family member 13 , cadherin family member 13 , desmoglein-4 , lanceolate hair

GENE ID SPECIES
537755 Bos taurus
612592 Canis lupus familiaris
743297 Pan troglodytes
100065957 Equus caballus
100414081 Callithrix jacchus
100454393 Pongo abelii
100468693 Ailuropoda melanoleuca
100543458 Meleagris gallopavo
100591286 Nomascus leucogenys
147409 Homo sapiens
16769 Mus musculus
291754 Rattus norvegicus
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