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DRG2 encodes a GTP-binding protein known to function in the regulation of cell growth and differentiation. Additionally we are shipping DRG2 Antibodies (30) and DRG2 Kits (3) and many more products for this protein.
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Authors observed that knockdown of DRG2 in HeLa cells affected growth in a wound-healing assay, and tumorigenicity in nude mice xenografts.
Results demonstrate that DRG2 is an endosomal protein and a key regulator of Rab5 (show RAB5A Proteins) deactivation and Tfn (show Tf Proteins) recycling.
miR19153p functions as a silencer of apoptosis, which regulates lung cancer apoptosis via targeting DRG2/PBX2 (show PBX2 Proteins).
Basal expression level of DRG2 is regulated by the Sp1 transcription factor (show SP1 Proteins).
overexpression of DRG2 in Jurkat cells affects genes regulating cell-cycle arrest and apoptosis, and that these molecular changes may be important in the growth or differentiation of cells
Developmentally regulated GTP-binding protein 2 ameliorates EAE by suppressing the development of TH17 cells.
DRG2 is associated with survival and cytoskeleton organization of osteoclasts under influence of macrophage colony-stimulating factor (show CSF2 Proteins), and its overexpression leads to elevated bone resorptive activity of osteoclasts, resulting in bone loss.
This gene encodes a GTP-binding protein known to function in the regulation of cell growth and differentiation. Read-through transcripts containing this gene and a downstream gene have been identified, but they are not thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome 17.
developmentally-regulated GTP-binding protein 2
, developmentally regulated GTP binding protein 2
, developmentally regulated GTP-binding protein 2