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Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH . Additionally we are shipping DiGeorge Syndrome Chromosome Region-2 Proteins (7) and many more products for this protein.
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Human Polyclonal DGS2 Primary Antibody for IHC, IHC (p) - ABIN4305115
Lindskog, Korsgren, Pontén, Eriksson, Johansson, Danielsson: Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new biomarker candidates. in Journal of proteomics 2012
Show all 2 Pubmed References
DGCR2, GPR44 (show PTGDR2 Antibodies) and SerpinB10 (show SERPINB10 Antibodies), found in beta cells, were negative in all other cell types within pancreas and exposed epitopes at the cell surface
Study confirmed the association between DGCR2 & schizophrenia through genotyping of 1,400 subjects; in a gene expression analysis, the risk allele of a coding SNP associated with schizophrenia was found to be associated with a reduced expression of DGCR2.
These data do not support a significant role of DGCR2 in the aetiology of schizophrenia in the German population.
GPIb alpha (show GP1BA Antibodies) contributes to the control of tumor metastasis, in addition to its role in hemostasis
Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.
integral membrane protein DGCR2/IDD
, CIDD protein
, DiGeorge syndrome critical region protein 2
, integral membrane protein deleted in DiGeorge syndrome
, DiGeorge syndrome gene c
, DiGeorge syndrome protein C
, seizure-related membrane-bound adhesion protein