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Diacylglycerol Kinase, zeta Proteins (DGKZ)

The protein encoded by DGKZ belongs to the eukaryotic diacylglycerol kinase family. Additionally we are shipping DGKZ Antibodies (51) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DGKZ 104418 Q80UP3
Rat DGKZ DGKZ 81821 O08560
DGKZ 8525 Q13574
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Top DGKZ Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$788.70
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$967.75
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

DGKZ Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

More Proteins for Diacylglycerol Kinase, zeta (DGKZ) Interaction Partners

Mouse (Murine) Diacylglycerol Kinase, zeta (DGKZ) interaction partners

  1. this is the first report implicating M-CSF/DGKzeta/DAG axis as a critical regulator of bone homeostasis via its actions on OC differentiation and c-Fos expression.

  2. another possible involvement of DGKzeta in the regulation of secretion of the terminal tubule cells, as well as its functional significance of its nuclear localization in the submandibular ganglion cells is discussed

  3. This study demonstrated that Diacylglycerol Kinase zeta with Protein Kinase (show CDK7 Proteins) Calpha (show PRKACA Proteins) Is Required for Cerebellar Long-Term Depression

  4. The results suggest that DGKzeta cytoplasmic translocation in neurons under hypoxic stress is regulated by some mechanism which differs from that mediated by NAP1 (show ABI1 Proteins)-like proteins.

  5. This study shows that DGKzeta knockdown facilitates degradation of IkappaB, followed by nuclear translocation of NF-kappaB (show NFKB1 Proteins) p65 (show NFkBP65 Proteins) subunit.

  6. DGKzeta regulates the development of natural Treg cells by limiting the extent of activation of the ERK (show EPHB2 Proteins) and c-Rel (show NFkBP65 Proteins) signaling pathways.

  7. The zeta isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling.

  8. Data demonstrate that miR (show MLXIP Proteins)-34a is a negative regulator for DGKzeta and may play an important role in regulating T cell activation.

  9. Data indicate that in the absence of DGKzeta, the threshold for B cell antigen receptor (BCR (show BCR Proteins)) signaling, measured as activation of the Ras-extracellular signal-regulated kinase (ERK (show EPHB2 Proteins)) pathway, was markedly reduced in mature follicular B cells.

  10. DGKzeta, but not PLD, plays an important role in mechanically induced increases in PA and mTOR (show FRAP1 Proteins) signaling.

Human Diacylglycerol Kinase, zeta (DGKZ) interaction partners

  1. This study shows that DGKzeta knockdown facilitates degradation of IkappaB, followed by nuclear translocation of NF-kappaB (show NFKB1 Proteins) p65 (show GORASP1 Proteins) subunit.

  2. Elevated DGKzeta expression contributes to increased Rho GTPase (show RACGAP1 Proteins) activation and the enhanced motility of metastatic cancer cells.

  3. Data indicate that after P2Y6 receptor stimulation both phospholipase D (PLD) and DGKzeta enzymes are responsible for producing phosphatidic acid (PA).

  4. DGK (show DGKB Proteins) regulates melanogenesis via modulation of the posttranslational processing of tyrosinase (show TYR Proteins), which may be related with the protein degradation machinery.

  5. DGK-zeta translocated rapidly to the plasma membrane at early stages of immunological synapse (IS) formation independent of enzyme activity; study highlights a DGKzeta-specific function for local diacylglycerol metabolism at the IS and offers new clues to its mode of regulation

  6. Antigen-specific CD8 (show CD8A Proteins)-positive T cells from DGKzeta-deficient transgenic mice show enhanced expansion and increased cytokine production after lymphocytic choriomeningitis virus infection, yet DGK (show DGKB Proteins)-deficient memory CD8 (show CD8A Proteins)+ T cells exhibit impaired expansion.

  7. Nucleosome assembly protein (NAP) 1-like 1 (NAP1L1 (show NAP1L1 Proteins)) and NAP1 (show IL8 Proteins)-like 4 (NAP1L4 (show NAP1L4 Proteins)) are identified as novel DGKzeta binding partners.

  8. PKC alpha (show PKCa Proteins) phosphorylates diacylglycerol kinase zeta in cells, and this phosphorylation inhibits its kinase activity to remove cellular diacylglycerol, thereby affecting cell growth.

  9. role in controlling the induction of luteinizing hormone beta transcription by ERK1/2

  10. DGKzeta generating PA, stimulates PIP5KIalpha activity to increase local PIP2, which regulates actin polymerization.

DGKZ Protein Profile

Protein Summary

The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified.

Gene names and symbols associated with DGKZ

  • diacylglycerol kinase, zeta (DGKZ)
  • diacylglycerol kinase, zeta a (dgkza)
  • diacylglycerol kinase zeta (CpipJ_CPIJ018790)
  • diacylglycerol kinase zeta (Dgkz)
  • DAGK5 protein
  • DAGK6 protein
  • DGK-ZETA protein
  • dgki protein
  • E130307B02Rik protein
  • ENSMUSG00000075035 protein
  • F730209L11Rik protein
  • hDGKzeta protein
  • mDGK[z] protein

Protein level used designations for DGKZ

diacylglycerol kinase zeta , diacylglycerol kinase, zeta 104kDa , diacylglycerol kinase, zeta , DAG kinase zeta , DGK-zeta , diglyceride kinase zeta , 104 kDa diacylglycerol kinase , DGK-IV

GENE ID SPECIES
423197 Gallus gallus
451153 Pan troglodytes
483635 Canis lupus familiaris
553380 Danio rerio
713198 Macaca mulatta
6052745 Culex quinquefasciatus
100050499 Equus caballus
100345732 Oryctolagus cuniculus
100431923 Pongo abelii
100519533 Sus scrofa
104418 Mus musculus
81821 Rattus norvegicus
8525 Homo sapiens
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