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Diaphanous Homolog 3 (Drosophila) (DIAPH3) ELISA Kits

DIAPH3 encodes a member of the diaphanous subfamily of the formin family. Additionally we are shipping DIAPH3 Antibodies (57) and DIAPH3 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat DIAPH3 DIAPH3 290396  
Anti-Mouse DIAPH3 DIAPH3 56419 Q9Z207
Anti-Human DIAPH3 DIAPH3 81624 Q9NSV4
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More ELISA Kits for DIAPH3 Interaction Partners

Mouse (Murine) Diaphanous Homolog 3 (Drosophila) (DIAPH3) interaction partners

  1. the interactome of auto-inhibited and constitutively active mDia2, is reported.

  2. mDia2-deficient erythroid cells differentiate normally, though in a delayed manner, but exhibit cytokinesis failure with decreased accumulation of F-actin in the cleavage furrow during late differentiation from proerythroblasts

  3. Diaphanous homolog 3 (Diap3) overexpression causes progressive hearing loss and inner hair cell defects in a transgenic mouse model of human deafness.

  4. Dia1 (show CYB5R3 ELISA Kits) and Dia2 are dynamic components of meiotic spindle and pole complex during meiotic maturation of oocytes.

  5. Microtubules strongly inhibit actin polymerization by mDia2.

  6. Results indicate that ROCK-dependent phosphorylation of the mDia2 DAD is an important determinant of mDia2 activity and that this signalling mechanism affects actin polymerization and smooth muscle cell-specific gene expression.

  7. Results show that targeting of mDia2 to the cleavage furrow requires not only its binding to RhoA (show RHOA ELISA Kits) but also its diaphanous-inhibitory domain, and identify anillin (show ANLN ELISA Kits) as a novel mDia2 interaction partner.

  8. Int (show TSC22D3 ELISA Kits)roduction of the mDia2 inhibitor DIP/WISH/SPIN90 into ce (show DIAPH2 ELISA Kits)lls triggers non-apoptotic membrane blebbing. The results infer a role for mDia2 in (show ACTR2 ELISA Kits)the maintenance of actin networks supporting the cell cortex.

  9. the bundling activities of FRL1 and mDia2, while producing phenotypically similar bundles, differ in mechanistic detail

  10. the DD/CC region is required for the Rho-independent membrane targeting of the isolated N terminus of mDia1 and mDia2

Human Diaphanous Homolog 3 (Drosophila) (DIAPH3) interaction partners

  1. we use a simple cellular system to examine fundamental features of formin (show FMN1 ELISA Kits)-mediated filopodial assembly, using constitutively active constructs of the formins mDia2 and FMNL3 (show FMNL3 ELISA Kits)

  2. results suggest that inhibition of MT stability arising from DIAPH3 downregulation enhances susceptibility to MT poisons, and that the DIAPH3 network potentially reports taxane sensitivity in human tumors

  3. Dia1 (show CYB5R3 ELISA Kits), Dia2 (show DIAPH2 ELISA Kits), and Dia3 (show DIAPH2 ELISA Kits) are involved in ErbB2 (show ERBB2 ELISA Kits)-dependent capture of microtubules at the cell leading edge and ErbB2 (show ERBB2 ELISA Kits)-driven guided migration.

  4. An mDia2/ROCK signaling axis regulates invasive egress from epithelial ovarian cancer spheroids.

  5. TGF-beta promotes association of mDia2 with actin stress fibers, which further drives stress fiber formation and myofibroblast differentiation

  6. In human tumours, DIAPH3 down-regulation was associated with aggressive or metastatic disease.

  7. isoform-selective actin assembly by DIAPH3 exerts specific and differentially regulated functions during cell adhesion and motility.

  8. the amino terminus of mDia2 serves as a coincidence detection module, directing mDia2 to the plasma membrane through interactions with phospholipids and activated Rif

  9. These findings reveal a key role for mDia3 and its regulation by Aurora B (show AURKB ELISA Kits) phosphorylation in achieving proper stable kinetochore microtubule attachment.

  10. These studies further suggest that Rho GTPases significantly influence the activity of mDia family formins in driving cellular membrane remodeling through the regulation of actin dynamics.

DIAPH3 Antigen Profile

Antigen Summary

This gene encodes a member of the diaphanous subfamily of the formin family. Members of this family are involved in actin remodeling and regulate cell movement and adhesion. Mutations in this gene are associated with autosomal dominant auditory neuropathy 1. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DIAPH3

  • diaphanous-related formin 3 (Diaph3) antibody
  • diaphanous homolog 3 (Drosophila) (DIAPH3) antibody
  • diaphanous-related formin 3 (DIAPH3) antibody
  • diaphanous homolog 3 (Drosophila) (Diap3) antibody
  • 4930417P13Rik antibody
  • AN antibody
  • AUNA1 antibody
  • DIA2 antibody
  • diap3 antibody
  • Diaph3 antibody
  • DRF3 antibody
  • mDia2 antibody
  • mKIAA4117 antibody
  • NSDAN antibody
  • p134MDia2 antibody

Protein level used designations for DIAPH3

diaphanous homolog 3 , protein diaphanous homolog 3 , diaphanous homolog 3 (Drosophila) , protein diaphanous homolog 3-like , diaphanous-related formin , diaphanous-related formin-3

290396 Rattus norvegicus
418824 Gallus gallus
100174272 Pongo abelii
485474 Canis lupus familiaris
525628 Bos taurus
452752 Pan troglodytes
100051814 Equus caballus
100011744 Monodelphis domestica
100475459 Ailuropoda melanoleuca
100517419 Sus scrofa
56419 Mus musculus
81624 Homo sapiens
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