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Diazepam Binding Inhibitor Proteins (DBI)

DBI encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. Additionally we are shipping Diazepam Binding Inhibitor Antibodies (51) and Diazepam Binding Inhibitor Kits (16) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DBI 13167 P31786
DBI 1622 P07108
DBI 25045 P11030
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Top Diazepam Binding Inhibitor Proteins at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$313.50
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human His tag,S tag   100 μg Log in to see 11 to 13 Days
$422.40
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$437.80
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,132.17
Details
Yeast Dog His tag   1 mg Log in to see 56 to 66 Days
$2,132.17
Details

DBI Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,
Rat (Rattus)

Top referenced Diazepam Binding Inhibitor Proteins

  1. Human Diazepam Binding Inhibitor Protein expressed in Escherichia coli (E. coli) - ABIN667004 : Folli, Guzzi, Perego, Coletta, Finzi, Placidi, La Rosa, Capella, Socci, Lauro, Tripathy, Jenkinson, Paroni, Orsenigo, Cighetti, Gregorini, Staudacher, Secchi, Bachi, Brownlee, Fiorina: Proteomics reveals novel oxidative and glycolytic mechanisms in type 1 diabetic patients' skin which are normalized by kidney-pancreas transplantation. in PLoS ONE 2010 (PubMed)
    Show all 2 references for ABIN667004

More Proteins for Diazepam Binding Inhibitor (DBI) Interaction Partners

Mouse (Murine) Diazepam Binding Inhibitor (DBI) interaction partners

  1. Mice with conditional targeting of the Acbp gene in the epidermis recapitulate this phenotype, whereas generation of an artificial epidermal barrier during gland development reverses the phenotype

  2. This study demonistrated that a novel role for ACBP in brain lipid metabolism.

  3. Acyl-CoA binding protein and epidermal barrier function. [review]

  4. ACBP is required for production of VLC-FFA for stratum corneum and for maintaining normal epidermal barrier function

  5. It was concluded that acyl-CoA binding protein via aquaporin 3 (show AQP3 Proteins) is necessary for intact urine concentrating ability through efflux over the basolateral membrane of the collecting duct.

  6. Diazepam binding inhibitor promotes progenitor proliferation in the postnatal SVZ by reducing GABA signaling.

  7. lack of ACBP interferes with the normal metabolic adaptation to weaning and leads to delayed induction of the lipogenic gene program in the liver

  8. Acyl-CoA binding protein gene ablation induces pre-implantation embryonic lethality in mice

  9. Acute food deprivation reduces expression of diazepam-binding inhibitor in mouse glial cells.

  10. the present study revealed a definite existence of DBI in non-neuronal supporting cells in both the central and peripheral nervous systems.

Human Diazepam Binding Inhibitor (DBI) interaction partners

  1. Serum endozepine-4 levels are increased in hepatic coma.

  2. Structural and functional properties of ACBD1, commonly known as ACBP (show CPN2 Proteins). [Review]

  3. High ACBP (show CPN2 Proteins) expression is associated with non-small cell lung cancer.

  4. results indicate that a dysfunction of the neurosteroid system might be operative in BPD in spite of unchanged DBI plasma levels.

  5. There was a significant difference in the rs2276596 polymorphism C/A allele frequency of the DBI gene (P < 0.0001) between alcoholics and healthy controls.

  6. Acyl-CoA binding protein and epidermal barrier function. [review]

  7. Endogenous potentiation of GABAergic synaptic transmission and responses to GABA uncaging in the thalamic reticular nucleus is absent in mice in which DBI is deleted and mice in which benzodiazepine binding to alpha3 subunit-containing GABAARs is disrupted.

  8. A human preadipocyte cell line SGBS (show GPC3 Proteins) is well suited to examine differential expression of the Acyl-CoA binding protein (ACBP) during adipogenesis.

  9. The regulation of novel low-abundance transcript variants of human acyl-CoA binding protein, was analysed.

  10. Gene annotation enrichment analysis revealed ACBP (show CPN2 Proteins)-mediated down-regulation of 18 genes encoding key enzymes in glycerolipid, cholesterol and fatty acid metabolism.

Cow (Bovine) Diazepam Binding Inhibitor (DBI) interaction partners

  1. The denatured state of ACBP at near-zero denaturant is unusually compact and enriched in long-range structure that can be perturbed by discrete hydrophobic core mutations.

  2. Results describe the folding kinetics of bovine acyl-CoA binding protein as measured by 15N relaxation dispersion measurements under equilibrium conditions.

Diazepam Binding Inhibitor (DBI) Protein Profile

Protein Summary

This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with DBI

  • diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (dbi)
  • diazepam binding inhibitor (dbi) (dbi)
  • diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI)
  • diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) (DBI)
  • diazepam-binding inhibitor (dbi)
  • diazepam binding inhibitor (dbi) b (dbib)
  • carboxypeptidase N, polypeptide 2 (CPN2)
  • diazepam binding inhibitor (Dbi)
  • diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (Dbi)
  • ACBD1 protein
  • Acbp protein
  • Acoabp3 protein
  • CCK-RP protein
  • DBI protein
  • dbib protein
  • endozepine protein
  • Ep protein
  • Odn protein
  • RNACOABP3 protein
  • Ttn protein
  • wu:fb63e10 protein
  • zgc:56108 protein
  • zgc:77734 protein

Protein level used designations for DBI

diazepam binding inhibitor , diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) , diazepam-binding protein , diazepam-binding inhibitor , acyl CoA binding protein , acyl-CoA-binding protein , endozepine , acyl-CoA binding protein , diazepam binding inhibitor, splice form 1b , GABA receptor modulator , acyl coenzyme A binding protein , acyl-Coenzyme A binding domain containing 1 , cholecystokinin-releasing peptide, trypsin-sensitive , Diazepam binding inhibitor (GABA receptor modulator acyl-Coenxyme A binding protein) , Diazepam binding inhibitor (GABA receptor modulator, acyl-Coenxyme A binding protein) , LRRGT00046 , octadecaneuropeptide , triakontatetraneuropeptide , ACBP , EP

GENE ID SPECIES
393831 Danio rerio
394469 Xenopus (Silurana) tropicalis
459574 Pan troglodytes
706367 Macaca mulatta
6358314 Burkholderia multivorans ATCC 17616
100036821 Xenopus laevis
100008823 Oryctolagus cuniculus
13167 Mus musculus
1622 Homo sapiens
25045 Rattus norvegicus
397212 Sus scrofa
768330 Bos taurus
395263 Gallus gallus
476115 Canis lupus familiaris
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