anti-Diazepam Binding Inhibitor (DBI) Antibodies

DBI encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. Additionally we are shipping Diazepam Binding Inhibitor Proteins (31) and Diazepam Binding Inhibitor Kits (28) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DBI 1622 P07108
DBI 13167 P31786
DBI 25045 P11030
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Top anti-Diazepam Binding Inhibitor Antibodies at antibodies-online.com

Showing 10 out of 86 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemistry with Brain, cerebellum tissue at an antibody concentration of 5µg/ml using anti-DBI antibody (ARP33135_P050) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-DBI antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958384 concentration 5 ug/ml. 50 μg Log in to see 7 to 9 Days
$676.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Mouse Un-conjugated IHC (p), IP, ELISA Anti-DBI antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN957757 dilution 1:200. 50 μL Log in to see 7 to 9 Days
$451.00
Details
Human Mouse Un-conjugated IHC (p), IP, ELISA, WB Anti-DBI antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN957761 dilution 1:200. 50 μL Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), IP, WB Anti-DBI antibody IHC staining of human spleen, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN957788 dilution 1:400. 50 μL Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 4 to 6 Days
$240.00
Details

DBI Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine)


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Rat (Rattus)


Top referenced anti-Diazepam Binding Inhibitor Antibodies

  1. Cow (Bovine) Polyclonal Diazepam Binding Inhibitor Primary Antibody for IHC, WB - ABIN2777771 : Waga, Ikeda, Iwahashi: The relationship between alcoholism and DBI gene polymorphism in Japanese--genotyping of the +529A/T in DBI gene polymorphism based on PCR. in Nihon Arukōru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence 2008 (PubMed)

More Antibodies against Diazepam Binding Inhibitor Interaction Partners

Mouse (Murine) Diazepam Binding Inhibitor (DBI) interaction partners

  1. DBI is expressed in stem cells in all neurogenic niches of the postnatal brain. DBI regulates the balance between preserving the stem cell pool and neurogenesis. Specifically, DBI dampens GABA activity in stem cells, thereby sustaining the proproliferative effect of physical exercise and enriched environment.

  2. ACBP increases the activity of ceramide synthase 2 (CerS2 (show CERS2 Antibodies)) by more than 2-fold and CerS3 (show CERS3 Antibodies) activity by 7-fold. ACBP binds very-long-chain acyl-CoA (show GNPAT Antibodies) esters, which is required for its ability to stimulate CerS activity.

  3. Mice with conditional targeting of the Acbp gene in the epidermis recapitulate this phenotype, whereas generation of an artificial epidermal barrier during gland development reverses the phenotype

  4. This study demonistrated that a novel role for ACBP in brain lipid metabolism.

  5. Acyl-CoA binding protein and epidermal barrier function. [review]

  6. ACBP is required for production of VLC-FFA for stratum corneum and for maintaining normal epidermal barrier function

  7. It was concluded that acyl-CoA binding protein via aquaporin 3 (show AQP3 Antibodies) is necessary for intact urine concentrating ability through efflux over the basolateral membrane of the collecting duct.

  8. Diazepam binding inhibitor promotes progenitor proliferation in the postnatal SVZ by reducing GABA signaling.

  9. lack of ACBP interferes with the normal metabolic adaptation to weaning and leads to delayed induction of the lipogenic gene program in the liver

  10. Acyl-CoA binding protein gene ablation induces pre-implantation embryonic lethality in mice

Human Diazepam Binding Inhibitor (DBI) interaction partners

  1. ACBP (show CPN2 Antibodies) increases the activity of ceramide synthase 2 (CerS2 (show CERS2 Antibodies)) by more than 2-fold and CerS3 (show CERS3 Antibodies) activity by 7-fold. ACBP (show CPN2 Antibodies) binds very-long-chain acyl-CoA (show GNPAT Antibodies) esters, which is required for its ability to stimulate CerS activity.

  2. Serum endozepine-4 levels are increased in hepatic coma.

  3. Structural and functional properties of ACBD1, commonly known as ACBP (show CPN2 Antibodies). [Review]

  4. High ACBP (show CPN2 Antibodies) expression is associated with non-small cell lung cancer.

  5. results indicate that a dysfunction of the neurosteroid system might be operative in BPD (show MOD(MDG4) Antibodies) in spite of unchanged DBI (show TSPO Antibodies) plasma levels.

  6. There was a significant difference in the rs2276596 polymorphism C/A allele frequency of the DBI (show TSPO Antibodies) gene (P < 0.0001) between alcoholics and healthy controls.

  7. Acyl-CoA binding protein and epidermal barrier function. [review]

  8. Endogenous potentiation of GABAergic synaptic transmission and responses to GABA uncaging in the thalamic reticular nucleus is absent in mice in which DBI (show TSPO Antibodies) is deleted and mice in which benzodiazepine binding to alpha3 subunit-containing GABAARs is disrupted.

  9. A human preadipocyte cell line SGBS (show GPC3 Antibodies) is well suited to examine differential expression of the Acyl-CoA binding protein (ACBP) during adipogenesis.

  10. The regulation of novel low-abundance transcript variants of human acyl-CoA binding protein, was analysed.

Cow (Bovine) Diazepam Binding Inhibitor (DBI) interaction partners

  1. The denatured state of ACBP at near-zero denaturant is unusually compact and enriched in long-range structure that can be perturbed by discrete hydrophobic core mutations.

  2. Results describe the folding kinetics of bovine acyl-CoA binding protein as measured by 15N relaxation dispersion measurements under equilibrium conditions.

Diazepam Binding Inhibitor (DBI) Antigen Profile

Protein Summary

This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with DBI

  • diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI) antibody
  • diazepam binding inhibitor (dbi) b (dbib) antibody
  • carboxypeptidase N, polypeptide 2 (CPN2) antibody
  • diazepam-binding inhibitor (dbi) antibody
  • diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (dbi) antibody
  • diazepam binding inhibitor (dbi) (dbi) antibody
  • diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) (DBI) antibody
  • diazepam binding inhibitor (Dbi) antibody
  • diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (Dbi) antibody
  • ACBD1 antibody
  • Acbp antibody
  • Acoabp3 antibody
  • CCK-RP antibody
  • DBI antibody
  • dbib antibody
  • endozepine antibody
  • Ep antibody
  • Odn antibody
  • RNACOABP3 antibody
  • Ttn antibody
  • wu:fb63e10 antibody
  • zgc:56108 antibody
  • zgc:77734 antibody

Protein level used designations for DBI

GABA receptor modulator , acyl coenzyme A binding protein , acyl-CoA-binding protein , acyl-Coenzyme A binding domain containing 1 , cholecystokinin-releasing peptide, trypsin-sensitive , diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) , diazepam-binding inhibitor , endozepine , diazepam binding inhibitor , acyl CoA binding protein , diazepam-binding protein , ACBP , EP , acyl-CoA binding protein , diazepam binding inhibitor, splice form 1b , Diazepam binding inhibitor (GABA receptor modulator acyl-Coenxyme A binding protein) , Diazepam binding inhibitor (GABA receptor modulator, acyl-Coenxyme A binding protein) , LRRGT00046 , octadecaneuropeptide , triakontatetraneuropeptide , diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)

GENE ID SPECIES
1622 Homo sapiens
100036821 Xenopus laevis
100008823 Oryctolagus cuniculus
6358314 Burkholderia multivorans ATCC 17616
393831 Danio rerio
394469 Xenopus (Silurana) tropicalis
476115 Canis lupus familiaris
459574 Pan troglodytes
397212 Sus scrofa
706367 Macaca mulatta
768330 Bos taurus
395263 Gallus gallus
13167 Mus musculus
25045 Rattus norvegicus
100049822 Equus caballus
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