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anti-Dihydrofolate Reductase (DHFR) Antibodies

Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. Additionally we are shipping Dihydrofolate Reductase Proteins (34) and Dihydrofolate Reductase Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DHFR 1719 P00374
DHFR 13361 P00375
DHFR 24312 Q920D2
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Top anti-Dihydrofolate Reductase Antibodies at antibodies-online.com

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated EIA, WB Western blot analysis of DHFR antibody (C-term) in mouse liver tissue lysates (35ug/lane). KLF4 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Dog Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of DHFR on RSV-3T3 lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of DHFR. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated IHC (p) 7 mL Log in to see 21 to 31 Days
$237.00
Details
Mouse Rabbit Un-conjugated IHC (p), WB Western blot analysis of DHFR antibody (C-term) (ABIN391566) in mouse liver tissue lysates (35 µg/lane). KLF4 (arrow) was detected using the purified polyclonal antibody. DHFR Antibody (C-term) (ABIN391566) IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- DHFR Picoband antibody, Western blotting All lanes: Anti DHFR  at 0.5ug/ml WB: Recombinant Human DHFR Protein 0.5ng Predicted bind size: 32KD Observed bind size: 32KD Anti- DHFR Picoband antibody,IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to DHFR on HeLa cell. [antibody concentration 10 ug/ml] DHFR monoclonal antibody (M01), clone 2B10 Western Blot analysis of DHFR expression in HeLa . 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IHC, WB Immunohistochemical staining of paraffin-embedded breast tissue using anti-DHFR mouse monoclonal antibody. (ABIN2452470, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-DHFR mouse monoclonal antibody. (ABIN2452470, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, IHC, WB Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-DHFR mouse monoclonal antibody. (ABIN2452616, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Carcinoma of kidney tissue using anti-DHFRmouse monoclonal antibody. (ABIN2452616, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IF, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$529.83
Details

DHFR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-Dihydrofolate Reductase Antibodies

  1. Human Monoclonal Dihydrofolate Reductase Primary Antibody for IF, ELISA - ABIN560600 : Ionova, Vásquez-Vivar, Whitsett, Herrnreiter, Medhora, Cooley, Pieper: Deficient BH4 production via de novo and salvage pathways regulates NO responses to cytokines in adult cardiac myocytes. in American journal of physiology. Heart and circulatory physiology 2008 (PubMed)
    Show all 6 references for ABIN560600

  2. Dog (Canine) Monoclonal Dihydrofolate Reductase Primary Antibody for IF, IP - ABIN968118 : de Wind, Dekker, Claij, Jansen, van Klink, Radman, Riggins, van der Valk, vant Wout, te Riele: HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions. in Nature genetics 1999 (PubMed)
    Show all 5 references for ABIN968118

  3. Mouse (Murine) Polyclonal Dihydrofolate Reductase Primary Antibody for EIA, WB - ABIN453196 : Cody, Pace, Chisum, Rosowsky: New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring s in Proteins 2006 (PubMed)
    Show all 2 references for ABIN453196

More Antibodies against Dihydrofolate Reductase Interaction Partners

Zebrafish Dihydrofolate Reductase (DHFR) interaction partners

  1. Dihydrofolate reductase is required for the development of heart and outflow tract in zebrafish.

Human Dihydrofolate Reductase (DHFR) interaction partners

  1. the highest expression of GGH (show GGH Antibodies) and EGFR (show EGFR Antibodies) was noted in the left-sided colon; the highest expression of DHFR, FPGS (show FPGS Antibodies), TOP1 (show TOP1 Antibodies) and ERCC1 (show ERCC1 Antibodies) was noted in the rectosigmoid, whereas TYMP (show TYMP Antibodies) expression was approximately equivalent in the right-sided colon and rectum

  2. Overexpression of miR (show MLXIP Antibodies)-192 inhibited cellular proliferation by binding DHFR. miR (show MLXIP Antibodies)-192 decreased cellular anchoring via the repression of ITGAV (show ITGAV Antibodies), ITGB1 (show ITGB1 Antibodies), ITGB3 (show ITGB3 Antibodies), and CD47 (show CD47 Antibodies)

  3. Data suggest that DHFR exhibits intrinsic activity kinetics that are temperature-independent; additional mass (i.e., incorporation of H, C, and N isotopes) has no effect on intrinsic activity kinetics or protein conformation/stability of DHFR.

  4. patients homozygous for the G allele of rs1053129 in the DHFR gene were more likely to have a metastasis (45%, P= 0.005), and the methylenetetetrahydrofolate reductase (MTHFR (show MTHFR Antibodies)) 677C allele was associated with higher degree of liver toxicity

  5. the association between cognitive outcomes with the 19-bp deletion DHFR polymorphism, folate status, and their interaction with high or normal plasma folate

  6. S-nitrosylation of DHFR at cysteine 7 by eNOS (show NOS3 Antibodies)-derived NO is crucial for DHFR stability.

  7. genetic association studies in cohort of healthy young adults in Ireland: Data suggest that a 19 bp deletion/insertion polymorphism within intron 1 of DHFR (rs70991108) is not associated with folate nutritional status in the population studied.

  8. Dihydrofolate Reductase and Thymidylate Synthase (show TYMS Antibodies) Transgenes Resistant to Methotrexate Interact to Permit Novel Transgene Regulation.

  9. results for the first time suggested the DHFR 19-bp D/D genotype may confer a reduced risk of NS-CL/P and might act as a protective factor against NS-CL/P in the Iranian subjects.

  10. Triple mutant haplotypes AIRNI (N51I+C59R+S108N) of the dhfr gene associated with pyrimethamine resistance were prevalent in Chirang district of Assam.

Mouse (Murine) Dihydrofolate Reductase (DHFR) interaction partners

  1. The study reports arrested hematopoiesis and vascular relaxation defects in mice with a point mutation, Thr136Ala substitution in Dhfr.

  2. S-nitrosylation of DHFR at cysteine 7 by eNOS (show NOS3 Antibodies)-derived NO is crucial for DHFR stability.

  3. demonstrate that dihydrofolate reductase activity is also a feature of the mitochondria in both rat and mouse but this is not due to a second enzyme

  4. Robust and processive unfolding/degradation of some substrates with very stable protein domains, including mDHFR and titin (show TTN Antibodies)(I27) .

  5. protects endothelial nitric oxide synthase (show NOS3 Antibodies) from uncoupling in tetrahydrobiopterin deficiency

  6. Dhfr has a role in folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation (show HELLS Antibodies)

  7. E2F (show E2F1 Antibodies)-responsive dihydrofolate reductase promoter regulates the balance between acetylation and methylation of histone H3 (show HIST3H3 Antibodies) lysine 9

  8. translocation of the DHFR domain was greatly impaired when it was separated from the signal-anchor sequence

  9. mechanical stability of mouse dihydrofolate reductase is dominated by local interactions within the protein structure

  10. Crystal structures are reported for NADPH (show FDXR Antibodies) ternary complexes with PY1011 and mouse DHFR (mDHFR), refined to 2.2 A resolution.

Cow (Bovine) Dihydrofolate Reductase (DHFR) interaction partners

  1. Hydrogen peroxide down regulates expression in response to angiotensin Ii and underlies endothelial nitric oxide synthase (show NOS3 Antibodies) dysfunction.

Dihydrofolate Reductase (DHFR) Antigen Profile

Protein Summary

Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.

Gene names and symbols associated with DHFR

  • dihydrofolate reductase (dhfr) antibody
  • dihydrofolate reductase (DHFR) antibody
  • dihydrofolate reductase (dhfR) antibody
  • dihydrofolate reductase (folA) antibody
  • dihydrofolate reductase (dfrA) antibody
  • dihydrofolate reductase DhfR (dhfR) antibody
  • dihydrofolate reductase (CNJ01940) antibody
  • dihydrofolate reductase (DDB_G0286755) antibody
  • Dihydrofolate reductase (Dhfr) antibody
  • Dihydrofolate reductase (Mesil_0096) antibody
  • Dihydrofolate reductase (Arch_0408) antibody
  • dihydrofolate reductase (Fbal_3367) antibody
  • dihydrofolate reductase (Ilyop_0482) antibody
  • dihydrofolate reductase (Lbys_2007) antibody
  • dihydrofolate reductase (Riean_0733) antibody
  • Dihydrofolate reductase (Mrub_1855) antibody
  • Dihydrofolate reductase (Poras_0766) antibody
  • dihydrofolate reductase (Halhy_3552) antibody
  • dihydrofolate reductase (Mesop_3614) antibody
  • dihydrofolate reductase (Dhfr) antibody
  • 8430436I03Rik antibody
  • AA607882 antibody
  • AI662710 antibody
  • AW555094 antibody
  • cb595 antibody
  • CG14887 antibody
  • DDBDRAFT_0187132 antibody
  • DDBDRAFT_0230113 antibody
  • DDB_0187132 antibody
  • DDB_0230113 antibody
  • dhfr antibody
  • Dhfr1 antibody
  • DHFRP1 antibody
  • Dmel\\CG14887 antibody
  • DYR antibody
  • ECK0049 antibody
  • F10_orf160 antibody
  • JW0047 antibody
  • tmrA antibody
  • zgc:86637 antibody

Protein level used designations for DHFR

dihydrofolate reductase , dihydrofolate reductase DhfR , CG14887-PA , CG14887-PB , Dhfr-PA , Dhfr-PB , Dihydrofolate reductase , Dihydrofolate reductase 1 (active)

GENE ID SPECIES
1055571 Citrobacter freundii
711268 Macaca mulatta
875311 Mycoplasma genitalium G37
2807610 Mycoplasma mobile 163K
876943 Mycoplasma pneumoniae M129
1488256 Saimiriine herpesvirus 2
944790 Escherichia coli str. K-12 substr. MG1655
1091594 Mycobacterium bovis AF2122/97
81882 Danio rerio
735442 Pan troglodytes
707382 Macaca mulatta
6762344 Streptococcus equi subsp. zooepidemicus MGCS10565
3254250 Cryptococcus neoformans var. neoformans JEC21
8625801 Dictyostelium discoideum AX4
42003 Drosophila melanogaster
9249572 Meiothermus silvanus DSM 9946
9260970 Arcanobacterium haemolyticum DSM 20595
9772220 Ferrimonas balearica DSM 9799
9867983 Ilyobacter polytropus DSM 2926
9955862 Leadbetterella byssophila DSM 17132
10001480 Riemerella anatipestifer ATCC 11845 = DSM 15868
8879963 Meiothermus ruber DSM 1279
10575250 Porphyromonas asaccharolytica DSM 20707
10587734 Haliscomenobacter hydrossis DSM 1100
10827453 Mesorhizobium opportunistum WSM2075
1719 Homo sapiens
609048 Canis lupus familiaris
13361 Mus musculus
24312 Rattus norvegicus
508809 Bos taurus
427317 Gallus gallus
100525912 Sus scrofa
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