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DLAT Proteins

(Dihydrolipoyl Transacetylase (DLAT))

This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.[provided by RefSeq, Oct 2009].

recommended

DLAT Protein (AA 169-273) (His-IF2DI Tag) (ABIN7122666)

DLAT Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

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recommended

DLAT Protein (AA 1-647) (GST tag) (ABIN1351656)

DLAT Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

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recommended

DLAT Protein (AA 87-647) (His tag) (ABIN3085256)

Crystallography grade DLAT Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

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DLAT Proteins by Grade

Find DLAT Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

DLAT Proteins by Origin

Find DLAT Proteins for a variety of species such as anti-Human DLAT, anti-Mouse DLAT, anti-Rat DLAT. The species listed below are among those available. Click on a link to go to the corresponding products.

DLAT Proteins by Source

Here you will find DLAT Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

DLAT Proteins by Protein Type

Here you can find DLAT Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

DLAT Proteins by Application

Find DLAT Proteins validated for a specific application such as WB, ELISA, SDS, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular DLAT Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

DLAT Protein (AA 169-273) (His-IF2DI Tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7122666

Quantity 50 μg

Datasheet Datasheet

DLAT Protein (AA 1-647) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1351656

Quantity 10 μg

Datasheet Datasheet

DLAT Protein (AA 87-647) (His tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN3085256

Quantity 1 mg

Datasheet Datasheet

DLAT Protein (AA 86-642) (His tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN3125046

Quantity 1 mg

Datasheet Datasheet

DLAT Protein (AA 374-631) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7403039

Quantity 100 μg

Datasheet Datasheet

DLAT Protein (AA 368-626) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7391693

Quantity 100 μg

Datasheet Datasheet

DLAT Protein (AA 93-640, partial) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN5709403

Quantity 100 μg

Datasheet Datasheet

DLAT Protein

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3009179

Quantity 100 μg

Datasheet Datasheet

DLAT Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2719517

Quantity 20 μg

Datasheet Datasheet

DLAT Protein (AA 78-632) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1475200

Quantity 1 mg

Datasheet Datasheet

DLAT Protein

Reactivity Human

Source

Validations

Cat. No. ABIN1062608

Quantity 1 mg

Datasheet Datasheet

Aliases for DLAT Proteins

midline uncoordinated (muc) Proteins
dihydrolipoamide S-acetyltransferase L homeolog (dlat.L) Proteins
dihydrolipoamide S-acetyltransferase (DLAT) Proteins
dihydrolipoamide S-acetyltransferase (Dlat) Proteins
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) (dlat) Proteins
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) (Dlat) Proteins
6332404G05Rik Proteins
anon-WO0118547.121 Proteins
DLAT Proteins
DLTA Proteins
Dmel\\CG5261 Proteins
EP(2)0816 Proteins
EP816 Proteins
PDC-E2 Proteins
PDCE2 Proteins
wu:fc14f10 Proteins
wu:fc21f08 Proteins
wu:fc86g11 Proteins
wu:fj57d06 Proteins

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DLAT Proteins by Grade

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DLAT Proteins by Protein Type

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Popular DLAT Proteins

Aliases for DLAT Proteins

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