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Dihydropyrimidine Dehydrogenase (DPYD) ELISA Kits

The protein encoded by DPYD is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Additionally we are shipping DPYD Antibodies (53) and DPYD Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DPYD 81656 O89000
DPYD 1806 Q12882
DPYD 99586 Q8CHR6
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Top DPYD ELISA Kits at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 26.9 pg/mL 62.5-1000 pg/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details
Mouse 0.054 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$757.89
Details
Rabbit 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 11 to 13 Days
$785.71
Details
Guinea Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 11 to 13 Days
$801.43
Details
Rat 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 11 to 13 Days
$832.86
Details
General 0.87ng/ml 1.56-100 ng/mL   96 Tests Log in to see 11 to 13 Days
$946.00
Details
Monkey 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 11 to 13 Days
$832.86
Details
Chicken 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 8 to 9 Days
$715.00
Details
Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 8 to 9 Days
$715.00
Details
Dog 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 11 to 13 Days
$801.43
Details

Top referenced DPYD ELISA Kits

  1. General DPYD ELISA Kit for Competition ELISA - ABIN1129485 : Abuohashish, Al-Rejaie, Al-Hosaini, Parmar, Ahmed: Alleviating effects of morin against experimentally-induced diabetic osteopenia. in Diabetology & metabolic syndrome 2013 (PubMed)
    Show all 2 references for ABIN1129485

  2. Human DPYD ELISA Kit for Sandwich ELISA - ABIN414994 : Li, Dong, Zhao, Tang, Chen, Ding, Men, Luo, Du, Ge, Tan, Cao, Liu: The upregulation of dihydropyrimidine dehydrogenase in liver is involved in acquired resistance to 5-fluorouracil. in European journal of cancer (Oxford, England : 1990) 2013 (PubMed)

More ELISA Kits for DPYD Interaction Partners

Human Dihydropyrimidine Dehydrogenase (DPYD) interaction partners

  1. Increases in gene expression levels of TYMP (show TYMP ELISA Kits), DPYD, and HIF1A (show HIF1A ELISA Kits) in tumor tissues at 7 days after the start of CRT (show SLC6A8 ELISA Kits) may be useful for predicting the efficacy of CRT (show SLC6A8 ELISA Kits) including S-1 or UFT

  2. There were not statistical significant differences between carriers of KRAS mutated alleles between SD and PD groups. No significant difference was found between response rates and toxicity and DPD or UGT1A1 (show UGT1A1 ELISA Kits) genotypes. Our results suggested that determination of DPD or UGT1A1 (show UGT1A1 ELISA Kits) genotypes could not be useful for predicting severe toxicity of irinotecan in our population.

  3. Study shows that somatic mutations of DPYD cause a switch in pyrimidine metabolism and promote gene expression of pyrimidine enzymes toward malignant progression.

  4. Results suggest that DPYD c.1129-5923 C>G/hapB3 have limited predictive value for severe toxicity to 5-FU based combination chemotherapy.

  5. oxaliplatin-based chemotherapy increases ERCC1 (show ERCC1 ELISA Kits) and DPYD expression levels; bevacizumab induces VEGFA (show VEGFA ELISA Kits) expression in metastatic colorectal cancer

  6. This study demonstrates the clinical validity of combined MIR27A/DPYD screening to identify patients at risk of severe FP-toxicity.

  7. The expression of dihydropyrimidine dehydrogenase and its correlation with survival in stage II/III gastric cancer patients

  8. We propose the gene activity score for translating DPYD genotype into phenotype--{REVIEW}

  9. Demonstrate a correlation between occurrence of DPYD gene variant c.496A>G and KRAS wild type status of colorectal cancer tissue.

  10. Single nucleotide polymorphisms (SNPs) in Dihydropyrimidine Dehydrogenase and UGT1A1 (show UGT1A1 ELISA Kits) influence fluoropyrimdines and irinotecan adverse events (AEs (show AES ELISA Kits)).

Mouse (Murine) Dihydropyrimidine Dehydrogenase (DPYD) interaction partners

  1. DPD gene expression is regulated first at the mRNA level when the hepatocytes enter the cell cycle. There is little regulation at the translational level. Cell proliferation rate is influences the enzyme activity modification.

Pig (Porcine) Dihydropyrimidine Dehydrogenase (DPYD) interaction partners

  1. Data show that dihydropyrimidine dehydrogenase residue H673 is required for active site closure, while S670 is important for substrate recognition.

DPYD Antigen Profile

Antigen Summary

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DPYD

  • dihydropyrimidine dehydrogenase (DPYD) antibody
  • dihydropyrimidine dehydrogenase b (dpydb) antibody
  • dihydropyrimidine dehydrogenase (dpyd) antibody
  • dihydropyrimidine dehydrogenase (EHI_012980) antibody
  • dihydropyrimidine dehydrogenase (AaeL_AAEL014199) antibody
  • dihydropyrimidine dehydrogenase (AaeL_AAEL010204) antibody
  • dihydropyrimidine dehydrogenase (EDI_044620) antibody
  • dihydropyrimidine dehydrogenase (pyd1) antibody
  • dihydropyrimidine dehydrogenase (Dpyd) antibody
  • dihydropyrimidine dehydrogenase (LOC100356889) antibody
  • 14.t00017 antibody
  • AI315208 antibody
  • DDBDRAFT_0189681 antibody
  • DDBDRAFT_0231100 antibody
  • DDB_0189681 antibody
  • DDB_0231100 antibody
  • DHP antibody
  • DHPDHASE antibody
  • DPD antibody
  • dpyd antibody
  • E330028L06Rik antibody
  • zgc:77205 antibody

Protein level used designations for DPYD

DHPDHase , DPD , dihydropyrimidine dehydrogenase [NADP(+)] , dihydrothymine dehydrogenase , dihydrouracil dehydrogenase , dihydropyrimidine dehydrogenase

GENE ID SPECIES
100173131 Pongo abelii
457047 Pan troglodytes
715672 Macaca mulatta
100057177 Equus caballus
405829 Danio rerio
447312 Xenopus laevis
3410647 Entamoeba histolytica HM-1:IMSS
5563876 Aedes aegypti
5573038 Aedes aegypti
5882869 Entamoeba dispar SAW760
8616259 Dictyostelium discoideum AX4
100604410 Nomascus leucogenys
81656 Rattus norvegicus
1806 Homo sapiens
99586 Mus musculus
100727906 Cavia porcellus
397109 Sus scrofa
281124 Bos taurus
479935 Canis lupus familiaris
429083 Gallus gallus
101109311 Ovis aries
100356889 Oryctolagus cuniculus
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