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Dimethylarginine Dimethylaminohydrolase 1 Proteins (DDAH1)

DDAH1 belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. Additionally we are shipping DDAH1 Antibodies (65) and DDAH1 Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DDAH1 23576 O94760
DDAH1 69219 Q9CWS0
DDAH1 64157 O08557
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Top DDAH1 Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$668.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,746.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,746.33
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$3,035.21
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

DDAH1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Top referenced DDAH1 Proteins

  1. Human DDAH1 Protein expressed in Escherichia coli (E. coli) - ABIN667244 : Nakagomi, Kiryu-Seo, Kimoto, Emson, Kiyama et al.: Dimethylarginine dimethylaminohydrolase (DDAH) as a nerve-injury-associated molecule: mRNA localization in the rat brain and its coincident up-regulation with neuronal NO synthase (nNOS) in ... in The European journal of neuroscience 1999 (PubMed)

More Proteins for Dimethylarginine Dimethylaminohydrolase 1 (DDAH1) Interaction Partners

Human Dimethylarginine Dimethylaminohydrolase 1 (DDAH1) interaction partners

  1. results suggest that miR (show MLXIP Proteins)-21 may regulate renal fibrosis by the Wnt (show WNT2 Proteins) pathway via directly targeting DDAH1

  2. The most significant associations were detected for PECAM1 (show PECAM1 Proteins)*V/V + DDAH1*C (OR = 4.17 CI 1.56-11.15 Pperm = 0.005)

  3. FoxO1 (show FOXO1 Proteins) regulates asymmetric dimethylarginine via downregulation of dimethylaminohydrolase 1 in HUVECs and subjects with carotid atherosclerosis.

  4. Inhibiting the expression of DDAH1, but not DDAH2 (show DDAH2 Proteins), resulted in a significant increase in the sensitivity of the EVT cell line SGHPL-4 to tumour necrosis factor (show TNF Proteins) related apoptosis inducing ligand (TRAIL) induced apoptosis

  5. Genebased analyses revealed associations of the DDAH1 gene with longitudinal Blood Pressure phenotypes, associations with essential hypertension, Blood Pressure salt sensitivity, preeclampsia, or preclinical stages of atherosclerosis.

  6. increased ADMA levels in rheumatoid arthritis do not appear to relate to DDAH (show DDAH2 Proteins) genetic polymorphisms

  7. DDAH1 deficiency attenuates endothelial cell cycle progression and angiogenesis.

  8. the advanced glycation end products-receptor (show AGER Proteins) for advanced glycation end products-mediated reactive oxygen species generation could be involved in endothelial dysfunction in diabetic end-stage renal disease patients

  9. DDAH1 genotypes were closely related to asymmetric dimethylarginine levels, but not to measures of endothelium-dependent vasodilation in an elderly population.

  10. Only the DDAH1-V1 transcript is responsible for ADMA metabolism, and transcript specific primers are recommended to determine DDAH1 mRNA expression.

Cow (Bovine) Dimethylarginine Dimethylaminohydrolase 1 (DDAH1) interaction partners

  1. dimethylargininase-1 inhibited upon specific Cys (show DNAJC5 Proteins)-S-nitrosylation.

  2. High-resolution crystal structures of DDAH (show DDAH2 Proteins) isoform 1 was presented.

  3. Demonstrate a critical role for DDAH-1 and endogenous methylarginines in the pathogenesis of endothelial dysfunction.

  4. DDAH-1 and DDAH-2 (show DDAH2 Proteins) manifest their effects through different mechanisms, the former of which is largely ADMA-dependent and the latter ADMA-independent.

Mouse (Murine) Dimethylarginine Dimethylaminohydrolase 1 (DDAH1) interaction partners

  1. In mild CKD, dysregulation of the ADMA/DDAH (show DDAH2 Proteins) pathway in adipose tissue triggers lipodystrophy-like phenotype changes, including ectopic fat depositions.

  2. Endothelial deletion of DDAH1 profoundly impairs the angiogenic capacity of endothelial cells.

  3. Our findings suggest that decreased expression of DDAH1 and DDAH2 (show DDAH2 Proteins) in the lungs may contribute to allergic asthma and overexpression of DDAH1 attenuates allergen-induced airway inflammation through modulation of Th2 responses.

  4. Overexpression of the ADMA degrading enzyme, DDAH1, did not ameliorate atherosclerosis in ApoE (show APOE Proteins)-deficient subtotally nephrectomized mice.

  5. DDAH1 deficiency attenuates endothelial cell cycle progression and angiogenesis.

  6. DDAH1 overexpression selectively decreased the sustained phase of hypoxic pulmonary vasoconstriction, partly via activation of the NO-cGMP pathway.

  7. Pharmacological and genetic reduction of DDAH1 activity is protective against the vascular changes observed during endotoxic shock.

  8. Data show that DDAH (show DDAH2 Proteins) inhibition reduces fibroblast-induced collagen deposition in an ADMA-independent manner and reduces abnormal epithelial proliferation in an ADMA-dependent manner.

  9. Indicate that DDAH1 is required for metabolizing asymmetrical dimethylarginine and N(omega)-monomethyl-L-arginine (show GATM Proteins).

  10. DDAH1 exerts a unique role in activating Akt (show AKT1 Proteins) that affects endothelial function independently of degrading endogenous nitirc oxide synthase inhibitors.

DDAH1 Protein Profile

Protein Summary

This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity.

Gene names and symbols associated with DDAH1

  • dimethylarginine dimethylaminohydrolase 1 (DDAH1)
  • dimethylarginine dimethylaminohydrolase 1 (ddah1)
  • dimethylarginine dimethylaminohydrolase 1 (LOC100339913)
  • dimethylarginine dimethylaminohydrolase 1 (Ddah1)
  • 2410006N07Rik protein
  • 2510015N06Rik protein
  • AI987801 protein
  • AW050362 protein
  • DDAH protein
  • DDAH1 protein
  • fc30c11 protein
  • wu:fc30c11 protein

Protein level used designations for DDAH1

dimethylarginine dimethylaminohydrolase 1 , DDAH-1 , DDAHI , N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 , NG, NG-dimethylarginine dimethylaminohydrolase , dimethylargininase-1 , NG,NG dimethylarginine dimethylaminohydrolase

GENE ID SPECIES
711395 Macaca mulatta
736613 Pan troglodytes
100145661 Xenopus (Silurana) tropicalis
100339913 Oryctolagus cuniculus
23576 Homo sapiens
537391 Bos taurus
69219 Mus musculus
114455 Danio rerio
380577 Xenopus laevis
378898 Gallus gallus
64157 Rattus norvegicus
490182 Canis lupus familiaris
100153814 Sus scrofa
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