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Discs, Large Homolog 1 (Drosophila) (DLG1) ELISA Kits

DLG1 encodes a multi-domain scaffolding protein that is required for normal development. Additionally we are shipping Discs, Large Homolog 1 (Drosophila) Antibodies (47) and Discs, Large Homolog 1 (Drosophila) Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat DLG1 DLG1 25252 Q62696
Anti-Mouse DLG1 DLG1 13383 Q811D0
Anti-Human DLG1 DLG1 1739 Q12959
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More ELISA Kits for Discs, Large Homolog 1 (Drosophila) Interaction Partners

Mouse (Murine) Discs, Large Homolog 1 (Drosophila) (DLG1) interaction partners

  1. Kif13b also negatively regulates Dlg1 stability in oligodendrocytes, in which Dlg1, in contrast to Schwann cells, enhances AKT (show AKT1 ELISA Kits) activation and promotes myelination

  2. Dlg1 regulates p38 (show CRK ELISA Kits)-dependent proinflammatory cytokine production.

  3. phenotypes of Dlg1-/- mice involving cellular disorganization and insufficient tissue elongation strongly suggest a defect in the convergent extension movements

  4. Loss of Dlg1 confers strong predisposition to the development of pediatric B-ALL in a murine model.

  5. data indicate that the surface expression and function of EAAT2b can be rapidly modulated through the disruption of its interaction with DLG1 by CaMKII (show CAMK2G ELISA Kits) activation.

  6. Loss of Dlg-1 in the mouse lens impairs fibroblast growth factor receptor signaling.

  7. lack of the Dlg1 gene induces a decrease in apoptotic epithelial cell death and the persistence of the common nephric duct, which result in a dysfunctional vesicoureteral junction and cause megaureter or hydronephrosis through vesicoureteral reflux

  8. DLG1 influences distal ureter maturation via a non-epithelial cell autonomous mechanism involving reduced retinoic acid signaling, Ret (show RET ELISA Kits) expression, and apoptosis.

  9. Synapse-associated protein 97 regulates the membrane properties of fast-spiking parvalbumin (show PVALB ELISA Kits) interneurons in the visual cortex in mice.

  10. DLG1 and CASK (show CASK ELISA Kits) play critical cooperative roles in maintaining the nephron progenitor population, potentially via a mechanism involving effects on FGF signaling

Human Discs, Large Homolog 1 (Drosophila) (DLG1) interaction partners

  1. Reduced cortical expression of a newly identified splicing variant of the DLG1 gene in patients with early-onset schizophrenia was identified.

  2. Human papillomavirus oncoproteins E6 and E7 induce the loss of DLG1 from the cell borders and an increase in the level of DLG1 protein, reflecting the pattern observed in cervical lesions.

  3. The study provides new evidence for understanding the transcriptional regulation of DLG1 and the changes in DLG1 expression during different biological processes.

  4. Trans-homophilic interaction of CADM1 (show CADM1 ELISA Kits) activates PI3K (show PIK3CA ELISA Kits) by forming a complex with MAGuK-family proteins MPP3 (show MPP3 ELISA Kits) and Dlg (show DLG4 ELISA Kits).

  5. the synapse-associated protein-97 (SAP97), an excitatory synapse scaffolding element, governs ADAM10 (show ADAM10 ELISA Kits) trafficking from dendritic Golgi outposts to synaptic membranes, mediated by a previously uncharacterized protein kinase C (show PKC ELISA Kits).

  6. E4-ORF1 (show NCKIPSD ELISA Kits) interacts with Dlg1 and PI3K (show PIK3CA ELISA Kits) to assemble a ternary complex where E4-ORF1 (show NCKIPSD ELISA Kits) hijacks the Dlg1 oncogenic function to relocate cytoplasmic PI3K (show PIK3CA ELISA Kits) to the membrane for constitutive activation.

  7. While other domains of SAP97 were involved in forward trafficking of GluN1 (show GRIN1 ELISA Kits)-3 out of the endoplasmic reticulum (ER), the SH3 domain (show ITSN1 ELISA Kits) was necessary and sufficient to block the ER retention.

  8. DLG1, XIST, DDX3Y and RPS4Y1 genes can classify samples into different group clearly, and they are regarded as high confidence distinct gene biomarkers of Parkinson disease.

  9. Novel genetic variants in the coding regions of DLG1 gene associated with susceptibility to Crohn's disease.

  10. These findings indicate that most, if not all, human adenovirus E4-ORF1 (show NCKIPSD ELISA Kits) proteins share a conserved molecular mechanism of PI3K (show PIK3CA ELISA Kits) activation via Dlg1 binding and confer a common capacity to promote oncogenic transformation.

Discs, Large Homolog 1 (Drosophila) (DLG1) Antigen Profile

Antigen Summary

This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene, but the full-length nature of some of the variants is not known.

Gene names and symbols associated with DLG1

  • discs, large homolog 1 (Drosophila) (DLG1) antibody
  • discs, large homolog 1 (Drosophila) (Dlg1) antibody
  • B130052P05Rik antibody
  • dJ1061C18.1.1 antibody
  • DLG1 antibody
  • DLGH1 antibody
  • E-dlg/SAP97 antibody
  • hdlg antibody
  • mKIAA4187 antibody
  • SAP-97 antibody
  • SAP97 antibody

Protein level used designations for DLG1

discs, large homolog 1 (Drosophila) , synapse-associated protein 97 , disks large homolog 1 , Drosophila discs-large tumor suppressor homologue (synapse associated protein) , SAP-97 , embryo-dlg/synapse-associated protein 97 , presynaptic protein SAP97

424890 Gallus gallus
460968 Pan troglodytes
709572 Macaca mulatta
785291 Bos taurus
100060094 Equus caballus
488036 Canis lupus familiaris
25252 Rattus norvegicus
13383 Mus musculus
1739 Homo sapiens
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