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DLG2 encodes a member of the membrane-associated guanylate kinase (MAGUK) family. Additionally we are shipping DLG2 Proteins (3) and many more products for this protein.
Showing 10 out of 85 products:
Human Polyclonal DLG2 Primary Antibody for ICC, IP - ABIN1742273
Requena, Parra, Baust, Quiroz, Leak, Garcia-Olivares, Torres: The molecular chaperone Hsc70 interacts with the vesicular monoamine transporter-2. in Journal of neurochemistry 2009
Show all 5 references for ABIN1742273
Human Monoclonal DLG2 Primary Antibody for IP, IHC - ABIN863118
Kim, Cho, Rothschild, Sheng: Heteromultimerization and NMDA receptor-clustering activity of Chapsyn-110, a member of the PSD-95 family of proteins. in Neuron 1996
Show all 2 references for ABIN863118
Human Polyclonal DLG2 Primary Antibody for WB - ABIN2781502
Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006
Show all 2 references for ABIN2781502
DLG2 - novel candidate genes validated in a large case-control sample of schizophrenia.
The PDZ1 domain of PSD-93 might accept peptides with larger residues at the C-terminus than that of PSD-95 (show DLG4 Antibodies), for example the GluD2 (show GLUD2 Antibodies) C-terminal Ile versus the Val found at the C-terminus of NMDA receptors.
This study showed that DLG2 is related the complex learning.
Comparison of the structures of the binding cleft of PSD-93 PDZ1 with the previously reported structures of PSD-93 PDZ2 and PDZ3 as well as of the closely related human PSD-95 (show DLG4 Antibodies) PDZ1 shows that they are very similar in terms of amino-acid composition
Variation at the DLG2 locus contributes to maintenance of glucose homeostasis through regulation of insulin (show INS Antibodies) sensitivity and beta-cell function.
Coexpression of Kir2.1 (show KCNJ2 Antibodies) and PSD (show PSD Antibodies)-93delta had no discernible effect upon channel kinetics but resulted in cell surface Kir2.1 (show KCNJ2 Antibodies) clustering and suppression of channel internalization.
identifies new isoform of DLG2 gene, which contains 3'-end exons of the known DLG2 gene along with the hypothetical gene FLJ37266; new isoform is specifically upregulated in renal oncocytoma
Downregulation of nAChR (show CHRNA4 Antibodies) subunit and PSD-93 expression after cavernous nerve injury, or even manipulation, could interrupt synaptic transmission within the MPG (show MPG Antibodies) and thus contribute to the loss of neural control of urogenital organs after pelvic surgeries.
Membrane-associated guanylate kinase (show GUK1 Antibodies) homolog PSD-93 is a central organizer of the postsynaptic density at excitatory synapses on pyramidal neurons.
These data show critical roles for psd-93 and interactions with NMDA receptor subunits in organizing the differential expression in rafts and postsynaptic densities of synaptic signaling complexes.
Since NMDARs, Ca(2 (show CA2 Antibodies)+), and NO play a critical role during the development of brain trauma, seizures, and ischemia, the present work suggests that PSD-93 might contribute to molecular mechanisms of neuronal damage in these brain disorders.
PSD-93 deficiency in knock-out mice results in a decrease in the minimum alveolar anesthetic concentration of halothane (show RYR1 Antibodies).
PSD-93 serves as a membrane-anchored substrate of Fyn (show FYN Antibodies) and plays a role in the regulation of Fyn (show FYN Antibodies)-mediated modification of NMDA receptor function
PSD93 containing complexes regulates synaptic stability at neuronal cholinergic synapses.
PSD-93 appears to mediate tyrosine-phosphorylation of the NMDA receptors
PSD-93 deficiency significantly decreased the amount of NR2A (show GRIN2A Antibodies) and NR2B (show GRIN2B Antibodies) in the synaptosomal membrane fractions
PSD-95 (show DLG4 Antibodies) and PSD-93 have distinct roles in synaptic plasticity, perhaps through differential recruitment of signalling molecules to the NMDA receptor.
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known.
, disks large homolog 2
, postsynaptic density protein 93
, channel-associated protein of synapse-110
, channel-associated protein of synapses, 110kDa
, discs, large homolog 2, chapsyn-110
, postsynaptic density protein PSD-93
, protein phosphatase 1, regulatory subunit 58
, discs large homolog 2
, synaptic density protein PSD-93