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anti-Discs, Large Homolog 5 (Drosophila) (DLG5) Antibodies

DLG5 encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DLG5 9231 Q8TDM6
DLG5 71228  
DLG5 305645  
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Top anti-DLG5 Antibodies at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged DLG5 is 3 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.96 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.33 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated IP   100 μL Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 9 to 11 Days
$313.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

DLG5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine) ,


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Rat (Rattus) ,


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More Antibodies against DLG5 Interaction Partners

Pig (Porcine) Discs, Large Homolog 5 (Drosophila) (DLG5) interaction partners

  1. Depletion of Dlg5 expression by knockdown promoted the expression of the mesenchymal marker proteins, fibronectin (show FN1 Antibodies) and alpha-smooth muscle actin (show ACTG2 Antibodies), and suppressed the expression of E-cadherin (show CDH1 Antibodies).

Human Discs, Large Homolog 5 (Drosophila) (DLG5) interaction partners

  1. These data suggest that inhibition of Dlg5 by DNA hypermethylation contributes to provoke invasive phenotypes in bladder tumor.

  2. Findings demonstrate that Dlg5 interacts with and inhibits the activity of Girdin (show CCDC88A Antibodies), thereby suppressing the migration of prostate cancer cells.

  3. DLG5 plays a role in cell migration, cell adhesion, precursor cell division, cell proliferation, epithelial cell polarity maintenance, and transmission of extracellular signals to the membrane and cytoskeleton.

  4. Overexpression of Dlg5 enhances the degradation of TGFBRI.

  5. Polymorphisms in the DLG5 gene were found to be associated with Crohn's disease patients in Malaysia.

  6. Examined the genetic association of DLG5 SNP P1371Q with inflammatory bowel disease and its interaction with R30Q in disease susceptibility. P1371Q is complementary to R30Q, with R30Q exhibiting a dominant effect in IBD susceptibility.

  7. Increased expression of discs large homolog 5 gene (show GPD1 Antibodies) is associated with ulcerative colitis.

  8. In the studied population, DLG5 R30Q was associated with all forms of IBD. An elevated presence of the R30Q variant was observed in all members of a familial IBD registry

  9. findings suggest that lp-dlg/KIAA0583 is a novel scaffolding protein that can link the vinexin (show Sorbs3 Antibodies)-vinculin (show VCL Antibodies) complex and beta-catenin (show CTNNB1 Antibodies) at sites of cell-cell contact

  10. Genetic variation in DLG5 is associated with inflammatory bowel disease

Mouse (Murine) Discs, Large Homolog 5 (Drosophila) (DLG5) interaction partners

  1. Dlg5 is required for Hh-induced enrichment of Kif7 (show KIF7 Antibodies) and Gli2 (show GLI2 Antibodies) at the tip of the cilium but is dispensable for Gpr161 (show GPR161 Antibodies) exit from the cilium and the consequent suppression of Gli3 (show GLI3 Antibodies) processing into its repressor form

  2. DLG5 is a MAGUK protein that regulates spine formation, synaptogenesis, and synaptic transmission in cortical neurons.

  3. Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis.

  4. Data report that Discs large (show DLG4 Antibodies) 5 (Dlg5), a member of the MAGUK family, is an interactor of CitK required for CitK polarization.

DLG5 Antigen Profile

Protein Summary

This gene encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, in addition to PDZ and SH3 domains, and are thought to function as scaffolding molecules at sites of cell-cell contact. The protein encoded by this gene localizes to the plasma membrane and cytoplasm, and interacts with components of adherens junctions and the cytoskeleton. It is proposed to function in the transmission of extracellular signals to the cytoskeleton and in the maintenance of epithelial cell structure. Alternative splice variants have been described but their biological nature has not been determined.

Gene names and symbols associated with DLG5

  • discs, large homolog 5 (Drosophila) (DLG5) antibody
  • discs, large homolog 5a (Drosophila) (dlg5a) antibody
  • discs, large homolog 5 (Drosophila) (Dlg5) antibody
  • 4933429D20Rik antibody
  • dlg5 antibody
  • LP-DLG antibody
  • mKIAA0583 antibody
  • P-DLG5 antibody
  • PDLG antibody
  • T25557 antibody
  • wu:fc28f03 antibody

Protein level used designations for DLG5

discs, large homolog 5 (Drosophila) , discs large homolog 5 , discs large protein , discs, large homolog 5 , disks large homolog 5 , discs large protein LP-DLG , discs large protein P-dlg , large type of P-DLG , placenta and prostate DLG

GENE ID SPECIES
703123 Macaca mulatta
423728 Gallus gallus
535699 Bos taurus
489061 Canis lupus familiaris
448848 Sus scrofa
569065 Danio rerio
100225167 Taeniopygia guttata
9231 Homo sapiens
71228 Mus musculus
305645 Rattus norvegicus
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