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DVL2 encodes a member of the dishevelled (dsh) protein family. Additionally we are shipping DVL2 Proteins (3) and many more products for this protein.
Showing 10 out of 97 products:
Human Polyclonal DVL2 Primary Antibody for EIA, WB - ABIN951919
Kikuchi, Niikura, Kitagawa, Kikuchi: Dishevelled, a Wnt signalling component, is involved in mitotic progression in cooperation with Plk1. in The EMBO journal 2010
Show all 4 references for ABIN951919
Cow (Bovine) Polyclonal DVL2 Primary Antibody for IHC, WB - ABIN2779458
Lee, Zhao, Moon, Yoon, Kim, An, Kwon, Hwang, Choi, Shim, Kim, Yang: Differential involvement of GABA system in mediating behavioral and neurochemical effect of acupuncture in ethanol-withdrawn rats. in Neuroscience letters 2008
Show all 2 references for ABIN2779458
Epsins are required for Dishevelled stability and Wnt (show WNT2 Antibodies) signalling activation in colon cancer development.
Dpr1 (show DACT1 Antibodies) promotes the ubiquitination of Dvl2 by pVHL (show VHL Antibodies) and mediates the protein aggregate-elicited autophagy initiation
Dvl2 binds to Rab35 (show RAB35 Antibodies) and activation is required for MCF-7 cell migration
Dvl-2 and Dvl-3 (show DVL3 Antibodies) have a widespread distribution in both the olfactory epithelium and olfactory bulb
Dullard (show DULLARD Antibodies) may play a role in the fine-tuning of WNT (show WNT2 Antibodies) signalling activity by modulating the expression of ligands/antagonists and the availability of Dvl2 protein during specification of the germ cell lineage.
loss of Dvl2 function in Vangl2(Lp (show VANGL2 Antibodies)/+) embryos did not exacerbate the Vangl2(Lp (show VANGL2 Antibodies)/+) neuronal migration phenotype
Identification of a novel Wnt5a (show WNT5A Antibodies)-CK1varepsilon-Dvl2-Plk1 (show PLK1 Antibodies)-mediated primary cilia disassembly pathway.
These findings suggest that Wnt5a (show WNT5A Antibodies)-Ror-Dishevelled signaling constitutes a core noncanonical Wnt (show WNT2 Antibodies) pathway that is conserved through evolution and is crucial during embryonic development.
Dvl2 has an inhibitory role in myogenesis and Stau1 (show STAU1 Antibodies) coordinates myogenesis through the regulation of Dvl2 mRNA.
GABARAPL1 (show GABARAPL1 Antibodies) negatively regulates Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling by mediating Dvl2 degradation through the autophagy pathway.
In pancreatic cancer cells, AF6 (show MLLT4 Antibodies) is expressed at reduced levels, causing Dvl2 to be upregulated and available to bind and enhance FOXE1 (show FOXE1 Antibodies)-induced trans-activation of Snail (show SNAI1 Antibodies), which promotes proliferation and metastasis.
The data suggest that the expression of DVL2 in colon tissue segments may be important in the pathogenesis of HSCR (show EDNRB Antibodies).
Elevated DVL2 expression is associated with drug resistance in colorectal cancer.
The interaction of Dvl2 with Dapper-1 (show DACT1 Antibodies) is involved in the negative regulation of Wnt (show WNT2 Antibodies) signaling.
APPL1 (show APPL1 Antibodies) is a positive regulator of Dvl2-dependent transcriptional activity of AP-1 (show FOSB Antibodies).
High expression of IGFBP7 (show IGFBP7 Antibodies) in fibroblasts induced by colorectal cancer cells is co-regulated by TGF-beta (show TGFB1 Antibodies) and Wnt (show WNT2 Antibodies) signaling in a Smad2 (show SMAD2 Antibodies)/3-Dvl2/3-dependent manner.
these results indicate that RNF185 (show RNF185 Antibodies) negatively regulates osteogenesis through the degradation of Dvl2 and down-regulation of canonical Wnt (show WNT2 Antibodies) signaling pathway and suggest a possible therapeutic target in osteoporosis.
IRS1 (show IRS1 Antibodies)/2 promotes EMT (show ITK Antibodies) and cell proliferation through stabilizing Dvl2.
CapZIP (show RCSD1 Antibodies), which has been shown to regulate ciliogenesis, is an ERK7 (show MAPK15 Antibodies) substrate, and that Dishevelled, which has also been shown to regulate ciliogenesis, facilitates ERK7 (show MAPK15 Antibodies) phosphorylation of CapZIP (show RCSD1 Antibodies) through binding to both ERK7 (show MAPK15 Antibodies) and CapZIP (show RCSD1 Antibodies).
Different Dvl proteins (Dvl1 (show DVL1 Antibodies), Dvl2, Dvl3 (show DVL3 Antibodies)) and the composition of dishevelled-beta-arrestin protein complexes contribute to the specific activation of individual branches of Wnt (show WNT2 Antibodies) signaling in Xenopus gastrulation.
these findings suggest that regulation of Dvl protein levels by NEDD4L (show NEDD4L Antibodies) is essential for convergent extension during early Xenopus embryogenesis.
findings reveal that, in response to Wnt (show WNT2 Antibodies) signalling, Dishevelled inhibits CSL (show SMPX Antibodies) transcription factors to regulate Notch (show NOTCH1 Antibodies) signalling and cell-fate decisions in vivo
Data show that maternal Dvl2 and 3 are required for convergence extension movements downstream of the dorsally localized signaling pathway activated by Xnr3, but not downstream of the pathway activated by activin (show Actbeta Antibodies).
The archenteron elongation is independent of Xdsh signaling, especially during the second half of gastrulation.
Subcellular localization is insufficient to account for the pathway specificity of Dishevelled in the canonical Wnt (show WNT2 Antibodies) versus PCP (show PRCP Antibodies) signaling cascades.
both Lgl and Dsh are required for normal apical-basal polarity of Xenopus ectodermal cells
Gain- and loss-of-function experiments suggest that Xdsh associates with ephrinB1 (show EFNB1 Antibodies) and mediates ephrinB1 (show EFNB1 Antibodies) signalling through downstream members of the PCP (show PRCP Antibodies) pathway during eye field formation.
The direct interaction of Dvl2 with AP-2 is important for Frizzled internalization and Frizzled/planar cell polarity signaling.
demonstrate that during early zebrafish development Nkd1 (show NKD1 Antibodies) does not alter either endogenous or exogenous levels of Dvl2
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
DSH homolog 2
, dishevelled, dsh homolog 2
, segment polarity protein dishevelled homolog DVL-2
, dishevelled 2
, dishevelled, dsh homolog 2 (Drosophila)
, dishevelled 2 (homologous to Drosophila dsh)
, dishevelled homolog
, dishevelled 2, dsh homolog