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Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2) ELISA Kits

DVL2 encodes a member of the dishevelled (dsh) protein family. Additionally we are shipping DVL2 Antibodies (97) and DVL2 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat DVL2 DVL2 303251  
Anti-Mouse DVL2 DVL2 13543 Q60838
Anti-Human DVL2 DVL2 1856 O14641
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More ELISA Kits for DVL2 Interaction Partners

Mouse (Murine) Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2) interaction partners

  1. Epsins are required for Dishevelled stability and Wnt (show WNT2 ELISA Kits) signalling activation in colon cancer development.

  2. Dpr1 (show DACT1 ELISA Kits) promotes the ubiquitination of Dvl2 by pVHL (show VHL ELISA Kits) and mediates the protein aggregate-elicited autophagy initiation

  3. Dvl2 binds to Rab35 (show RAB35 ELISA Kits) and activation is required for MCF-7 cell migration

  4. Dvl-2 and Dvl-3 (show DVL3 ELISA Kits) have a widespread distribution in both the olfactory epithelium and olfactory bulb

  5. Dullard (show DULLARD ELISA Kits) may play a role in the fine-tuning of WNT (show WNT2 ELISA Kits) signalling activity by modulating the expression of ligands/antagonists and the availability of Dvl2 protein during specification of the germ cell lineage.

  6. loss of Dvl2 function in Vangl2(Lp (show VANGL2 ELISA Kits)/+) embryos did not exacerbate the Vangl2(Lp (show VANGL2 ELISA Kits)/+) neuronal migration phenotype

  7. Identification of a novel Wnt5a (show WNT5A ELISA Kits)-CK1varepsilon-Dvl2-Plk1 (show PLK1 ELISA Kits)-mediated primary cilia disassembly pathway.

  8. These findings suggest that Wnt5a (show WNT5A ELISA Kits)-Ror-Dishevelled signaling constitutes a core noncanonical Wnt (show WNT2 ELISA Kits) pathway that is conserved through evolution and is crucial during embryonic development.

  9. Dvl2 has an inhibitory role in myogenesis and Stau1 (show STAU1 ELISA Kits) coordinates myogenesis through the regulation of Dvl2 mRNA.

  10. GABARAPL1 (show GABARAPL1 ELISA Kits) negatively regulates Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling by mediating Dvl2 degradation through the autophagy pathway.

Human Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2) interaction partners

  1. In pancreatic cancer cells, AF6 (show MLLT4 ELISA Kits) is expressed at reduced levels, causing Dvl2 to be upregulated and available to bind and enhance FOXE1 (show FOXE1 ELISA Kits)-induced trans-activation of Snail (show SNAI1 ELISA Kits), which promotes proliferation and metastasis.

  2. Epsins are required for Dishevelled stability and Wnt (show WNT2 ELISA Kits) signalling activation in colon cancer development.

  3. The data suggest that the expression of DVL2 in colon tissue segments may be important in the pathogenesis of HSCR (show EDNRB ELISA Kits).

  4. Elevated DVL2 expression is associated with drug resistance in colorectal cancer.

  5. Dpr1 (show DACT1 ELISA Kits) promotes the ubiquitination of Dvl2 by pVHL (show VHL ELISA Kits) and mediates the protein aggregate-elicited autophagy initiation

  6. The interaction of Dvl2 with Dapper-1 (show DACT1 ELISA Kits) is involved in the negative regulation of Wnt (show WNT2 ELISA Kits) signaling.

  7. APPL1 (show APPL1 ELISA Kits) is a positive regulator of Dvl2-dependent transcriptional activity of AP-1 (show FOSB ELISA Kits).

  8. High expression of IGFBP7 (show IGFBP7 ELISA Kits) in fibroblasts induced by colorectal cancer cells is co-regulated by TGF-beta (show TGFB1 ELISA Kits) and Wnt (show WNT2 ELISA Kits) signaling in a Smad2 (show SMAD2 ELISA Kits)/3-Dvl2/3-dependent manner.

  9. these results indicate that RNF185 (show RNF185 ELISA Kits) negatively regulates osteogenesis through the degradation of Dvl2 and down-regulation of canonical Wnt (show WNT2 ELISA Kits) signaling pathway and suggest a possible therapeutic target in osteoporosis.

  10. IRS1 (show IRS1 ELISA Kits)/2 promotes EMT (show ITK ELISA Kits) and cell proliferation through stabilizing Dvl2.

Xenopus laevis Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2) interaction partners

  1. CapZIP (show RCSD1 ELISA Kits), which has been shown to regulate ciliogenesis, is an ERK7 (show MAPK15 ELISA Kits) substrate, and that Dishevelled, which has also been shown to regulate ciliogenesis, facilitates ERK7 (show MAPK15 ELISA Kits) phosphorylation of CapZIP (show RCSD1 ELISA Kits) through binding to both ERK7 (show MAPK15 ELISA Kits) and CapZIP (show RCSD1 ELISA Kits).

  2. Different Dvl proteins (Dvl1 (show DVL1 ELISA Kits), Dvl2, Dvl3 (show DVL3 ELISA Kits)) and the composition of dishevelled-beta-arrestin protein complexes contribute to the specific activation of individual branches of Wnt (show WNT2 ELISA Kits) signaling in Xenopus gastrulation.

  3. these findings suggest that regulation of Dvl protein levels by NEDD4L is essential for convergent extension during early Xenopus embryogenesis.

  4. findings reveal that, in response to Wnt (show WNT2 ELISA Kits) signalling, Dishevelled inhibits CSL (show SMPX ELISA Kits) transcription factors to regulate Notch (show NOTCH1 ELISA Kits) signalling and cell-fate decisions in vivo

  5. Data show that maternal Dvl2 and 3 are required for convergence extension movements downstream of the dorsally localized signaling pathway activated by Xnr3, but not downstream of the pathway activated by activin (show Actbeta ELISA Kits).

  6. The archenteron elongation is independent of Xdsh signaling, especially during the second half of gastrulation.

  7. Subcellular localization is insufficient to account for the pathway specificity of Dishevelled in the canonical Wnt (show WNT2 ELISA Kits) versus PCP (show PRCP ELISA Kits) signaling cascades.

  8. both Lgl and Dsh are required for normal apical-basal polarity of Xenopus ectodermal cells

  9. Gain- and loss-of-function experiments suggest that Xdsh associates with ephrinB1 (show EFNB1 ELISA Kits) and mediates ephrinB1 (show EFNB1 ELISA Kits) signalling through downstream members of the PCP (show PRCP ELISA Kits) pathway during eye field formation.

  10. The direct interaction of Dvl2 with AP-2 is important for Frizzled internalization and Frizzled/planar cell polarity signaling.

Zebrafish Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2) interaction partners

  1. demonstrate that during early zebrafish development Nkd1 (show NKD1 ELISA Kits) does not alter either endogenous or exogenous levels of Dvl2

DVL2 Antigen Profile

Antigen Summary

This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.

Gene names and symbols associated with DVL2

  • dishevelled, dsh homolog 2 (Drosophila) (DVL2) antibody
  • dishevelled segment polarity protein 2 (dvl2) antibody
  • dishevelled 2 (Dvl2) antibody
  • dishevelled 2, dsh homolog (Drosophila) (Dvl2) antibody
  • dishevelled segment polarity protein 2 (DVL2) antibody
  • dishevelled, dsh homolog 2 (Drosophila) (dvl2) antibody
  • dishevelled antibody
  • dsh antibody
  • dvl antibody
  • Dvl-2 antibody
  • wu:fc05d12 antibody
  • wu:fo71e09 antibody
  • wu:fp54a02 antibody
  • xdsh antibody
  • zgc:55372 antibody

Protein level used designations for DVL2

DSH homolog 2 , Dishevelled-2 , dishevelled, dsh homolog 2 , segment polarity protein dishevelled homolog DVL-2 , dishevelled 2 , dishevelled, dsh homolog 2 (Drosophila) , dishevelled-2 , dishevelled 2 (homologous to Drosophila dsh) , dishevelled homolog , dishevelled 2, dsh homolog

GENE ID SPECIES
100625452 Sus scrofa
780117 Xenopus (Silurana) tropicalis
455236 Pan troglodytes
100061612 Equus caballus
303251 Rattus norvegicus
13543 Mus musculus
1856 Homo sapiens
399301 Xenopus laevis
323630 Danio rerio
489464 Canis lupus familiaris
614312 Bos taurus
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