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DVL3 is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. Additionally we are shipping DVL3 Antibodies (72) and DVL3 Proteins (4) and many more products for this protein.
Different Dvl (show DVL2 ELISA Kits) proteins (Dvl1 (show DVL1 ELISA Kits), Dvl2 (show DVL2 ELISA Kits), Dvl3) and the composition of dishevelled (show DVL2 ELISA Kits)-beta-arrestin protein complexes contribute to the specific activation of individual branches of Wnt (show WNT2 ELISA Kits) signaling in Xenopus gastrulation.
Data show that maternal Dvl2 (show DVL2 ELISA Kits) and 3 are required for convergence extension movements downstream of the dorsally localized signaling pathway activated by Xnr3, but not downstream of the pathway activated by activin (show Actbeta ELISA Kits).
Dvl-2 (show DVL2 ELISA Kits) and Dvl-3 have a widespread distribution in both the olfactory epithelium and olfactory bulb
Dvl3 is important for IPMK (show IPMK ELISA Kits) to access substrates and generate IP5, activating down-stream signaling.
Dishevelled (show DVL2 ELISA Kits)-KSRP (show KHSRP ELISA Kits) complex operates in Wnt (show WNT2 ELISA Kits) regulation of beta-catenin (show CTNNB1 ELISA Kits), functioning post-transcriptionally upon CTNNB1 (show CTNNB1 ELISA Kits) mRNA stability.
Dvl2 (show DVL2 ELISA Kits) and Dvl3 proteins were found to be localized to the apical side of the node cells, and their location was polarized to the posterior side of the cells before the posterior positioning of the basal body.
As embryos reach blastocyst stage, Dishevelled 2 (show DVL2 ELISA Kits) becomes increasingly associated with cell membrane in trophectoderm cells, while at E4.5, Dishevelled 3 is highly enriched in the cytoplasm of inner cell mass cells.
The expression of Dishevelleds in mammalian cells provide an estimate of the relative cellular abundance of each Dvl (show DVL1 ELISA Kits).
G alpha o (show GNAO1 ELISA Kits) mediates WNT (show WNT2 ELISA Kits)-JNK (show MAPK8 ELISA Kits) signaling through dishevelled 1 (show DVL1 ELISA Kits) and 3, RhoA (show RHOA ELISA Kits) family members, and MEKK 1 (show MAP2K1 ELISA Kits) and 4 in mammalian cells
Dvl1 (show DVL1 ELISA Kits), Dvl2 (show DVL2 ELISA Kits) and Dvl3 are functionally redundant in cardiac outflow tract, cochlea, and neural tube development.
Studied and identified candidate biomarkers of biochemical recurrence (BCR (show BCR ELISA Kits)) of prostate adenocarcinoma by integrating reverse-phase protein array (RPPA) and mRNA datafrom The Cancer Genome Atlas (TCGA). Found DVL3 was expressed in patients with a higher risk of BCR (show BCR ELISA Kits). DVL3 may be a novel and easily applicable recurrence predictor of localised prostate adenocarcinoma.
two mutually exclusive functions of the DEP (show ZDHHC21 ELISA Kits) domain in Wnt (show WNT2 ELISA Kits) signal transduction - binding to Frizzled to recruit Dishevelled (show DVL2 ELISA Kits) to the receptor complex, is reported.
Genetic changes between MLH1 (show MLH1 ELISA Kits) and MSH2 (show MSH2 ELISA Kits) were significantly positively correlated (p = 0.032). We also noted a positive correlation between genetic changes of MSH2 (show MSH2 ELISA Kits) and DVL3 genes (p = 0.034).
Data show that dishevelled (show DVL2 ELISA Kits) proteins DVL1 (show DVL1 ELISA Kits), 2 and 3 were exclusively expressed in chronic lymphatic leukaemia (CLL) cells as compared to normal peripheral blood mononuclear cells (PBMCs).
Kif26b, together with Dvl3/Daam1 (show DAAM1 ELISA Kits), initiates cell polarity through the control of planar cell polarity-signaling pathway-dependent activation in endothelial cells.
DVL3 transcripts decreased in individuals with major depressive disorder
we demonstrate that normally ALFY (show WDFY3 ELISA Kits) attenuates the canonical Wnt (show WNT2 ELISA Kits) signaling pathway via autophagy-dependent removal specifically of aggregates of DVL3 and not of Dvl1 (show DVL1 ELISA Kits) or Dvl2 (show DVL2 ELISA Kits).
All variants in DVL3 result in a -1 frameshift, indicating that these highly specific alterations might be a common cause of dominant Robinow syndrome.
data suggest that miR (show MLXIP ELISA Kits)-204-5p regulates adipogenesis by controlling DVL3 expression and subsequently inhibiting the activation of the Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling pathway.
findings confirm that p38 (show CRK ELISA Kits) and PAX2 (show PAX2 ELISA Kits) are important for the Dvl-3 induced upregulation of p120ctn (show CTNND1 ELISA Kits)
This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.
DSH homolog 3
, dishevelled, dsh homolog 3
, segment polarity protein dishevelled homolog DVL-3
, dishevelled, dsh homolog 3 (Drosophila)
, dishevelled 3 (homologous to Drosophila dsh)
, dishevelled 3, dsh homolog
, dishevelled 3
, dishevelled, dsh homolog 3a