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Probably involved in mitochondrial protein import. Additionally we are shipping DnaJ (Hsp40) Homolog, Subfamily B, Member 1 Kits (47) and DnaJ (Hsp40) Homolog, Subfamily B, Member 1 Proteins (18) and many more products for this protein.
Showing 10 out of 268 products:
Plasmodium falciparum Polyclonal DNAJB1 Primary Antibody for ICC, IF - ABIN361685
Melville, Hansen, Freeman, Welch, Katze: The molecular chaperone hsp40 regulates the activity of P58IPK, the cellular inhibitor of PKR. in Proceedings of the National Academy of Sciences of the United States of America 1997
Show all 9 references for ABIN361685
Human Monoclonal DNAJB1 Primary Antibody for ICC, IF - ABIN361668
Lu, Cyr: Protein folding activity of Hsp70 is modified differentially by the hsp40 co-chaperones Sis1 and Ydj1. in The Journal of biological chemistry 1998
Show all 8 references for ABIN361668
Yeast Monoclonal DNAJB1 Primary Antibody for IP, ELISA - ABIN361660
Höhfeld, Cyr, Patterson: From the cradle to the grave: molecular chaperones that may choose between folding and degradation. in EMBO reports 2001
Show all 7 references for ABIN361660
Plasmodium falciparum Polyclonal DNAJB1 Primary Antibody for ICC, IF - ABIN2482314
Ohtsuka: Cloning of a cDNA for heat-shock protein hsp40, a human homologue of bacterial DnaJ. in Biochemical and biophysical research communications 1994
Show all 6 references for ABIN2482314
Plasmodium falciparum Polyclonal DNAJB1 Primary Antibody for ICC, IF - ABIN2482315
Hattori, Liu, Tohnai, Ueda, Kaneda, Kobayashi, Tanabe, Ohtsuka: Intracellular localization and partial amino acid sequence of a stress-inducible 40-kDa protein in HeLa cells. in Cell structure and function 1992
Show all 6 references for ABIN2482315
Human Polyclonal DNAJB1 Primary Antibody for IHC (p), WB - ABIN1882092
Ohtsuka, Hata: Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature. in Cell stress & chaperones 2001
Show all 4 references for ABIN1882092
Human Monoclonal DNAJB1 Primary Antibody for EIA, WB - ABIN317097
Kumar, Mitra: Heat shock protein 40 is necessary for human immunodeficiency virus-1 Nef-mediated enhancement of viral gene expression and replication. in The Journal of biological chemistry 2005
Show all 2 references for ABIN317097
Cow (Bovine) Polyclonal DNAJB1 Primary Antibody for WB - ABIN2785888
Cheng, Belshan, Ratner: Hsp40 facilitates nuclear import of the human immunodeficiency virus type 2 Vpx-mediated preintegration complex. in Journal of virology 2008
Human Monoclonal DNAJB1 Primary Antibody for FACS, IF - ABIN2454060
Ramdzan, Polling, Chia, Ng, Ormsby, Croft, Purcell, Bogoyevitch, Ng, Gleeson, Hatters: Tracking protein aggregation and mislocalization in cells with flow cytometry. in Nature methods 2012
DNAJB1-PRKACA (show PRKACA Antibodies) was evaluated as a key driver of fibrolamellar carcinoma and as a candidate therapeutic target
siRNA experiments confirmed that a reduction in Hsp27 (show HSPB1 Antibodies) or Hsp40 rescued CFTR (show CFTR Antibodies) in the DeltaF508 mutant, but the rescue was not additive or synergistic with C4 + 18 treatment, indicating these correctors shared a common pathway for rescue
study provides a new molecular mechanism to regulate EGFR (show EGFR Antibodies) signaling through modulation of MIG6 (show ERRFI1 Antibodies) by DNAJB1 as a negative regulator.
Whole exome sequencing followed by immunohistochemistry of fibrolamellar hepatocellular carcinoma cell lines and tumors showed two structural variants resulting in fusion transcripts: DNAJB1-PRKCA (show PKCa Antibodies) and CLPTM1L (show CLPTM1L Antibodies)-GLIS3 (show GLIS3 Antibodies).
In this cohort of fibrolamellar hepatocellular carcinoma, almost 80% contained the DNAJB1-PRKACA (show PRKACA Antibodies) fusion transcript.
Authors identified DNAJB1 as a negative regulator of PDCD5 (show PDCD5 Antibodies)-mediated apoptosis and found that the apoptosis network of PDCD5 (show PDCD5 Antibodies) regulates cancer cell death.
We also found that, despite an initial report to the contrary, the human homolog of Sis1, Hdj1, is capable of [PSI+] prion (show PRNP Antibodies) propagation in place of Sis1
HSP40 interacts with pyruvate kinase M2 and regulates glycolysis and cell proliferation in tumor cells.
Studies with specific phosphoantibodies indicate that MK5 (show MAPKAPK5 Antibodies) phosphorylates Hsp40/DnaJB1 in vivo at Ser (show SIGLEC1 Antibodies)-149 or/and Ser (show SIGLEC1 Antibodies)-151 and Ser (show SIGLEC1 Antibodies)-171 in the C-terminal domain of Hsp40/DnaJB1.
Results show that TDP-43 (show TARDBP Antibodies) is constitutively bound to members of the Hsp40/Hsp70 (show HSP70 Antibodies) family, and that heat shock-induced TDP-43 (show TARDBP Antibodies) aggregation is mediated by the availability of these chaperones interacting with the inherently disordered C-terminal prion (show PRNP Antibodies) domain.
Through DnaJ-1, our data connect ataxin-3 (show ATXN3 Antibodies) and Rad23 to protective processes involved with protein folding rather than increased turnover of toxic polyQ species.
Expression of DnaJ-1 potently suppresses alpha1ACT-dependent degeneration , concomitant with decreased aggregation of the pathogenic protein. Mutating the nuclear importer karyopherin a3 (show KPNA4 Antibodies) also leads to reduced toxicity from pathogenic CACNA1A (show CACNA1A Antibodies)
HSP40 and HSP110 (show HSPH1 Antibodies) function together in protein homeostasis control.
A high positive correlation was found between the levels of Hsp40 expression and scores of basal and induced thermotolerance, implying a significant contribution of Hsp40 gene in thermoadaptation.
a biochemical link between Hsp40 expression and Abeta (show APP Antibodies)(42) proteostasis that is cell specific
Hsc70 (show HSPA8 Antibodies), Hdj1 and Hdj2 (show DNAJA1 Antibodies) interact with soluble and fibrillar alpha-synuclein (show SNCA Antibodies)
Hsp40, which was constitutively expressed in postmeiotic spermatogenic cells in testis, was integrated into spermatozoa as two components, that is, sperm head and tail of rodent spermatozoa.
HSP-40 expression was detected after 2 h of heat stress
a role for Hsp40 crosstalk with CSPalpha in neuroprotection.
This is a paper that uses purification techiques to find the following: Hsc40 (show DNAJB5 Antibodies), a new member of the hsp40 family, exhibits similar expression profile to that of hsc70 (show HSPA8 Antibodies) in mammalian cells.
Probably involved in mitochondrial protein import. Is also required for efficient translocation of pre-pro-alpha-factor. Involved in heme regulation of HAP1, as a component of the high- molecular-weight (HMC) complex.
, dnaJ like1
, Hsp40 protein
, DnaJ protein
, heat shock protein 40
, DnaJ (Hsp40) homolog, subfmaily B, member 1
, dnaJ homolog subfamily B member 1
, dnaJ protein homolog 1
, heat shock 40 kDa protein 1
, heat shock 40kD protein 1
, human DnaJ protein 1
, radial spoke 16 homolog B