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DnaJ (Hsp40) Homolog, Subfamily C, Member 10 Proteins (DNAJC10)

DNAJC10 encodes an endoplasmic reticulum co-chaperone which is part of the endoplasmic reticulum-associated degradation complex involved in recognizing and degrading misfolded proteins. Additionally we are shipping DnaJ (Hsp40) Homolog, Subfamily C, Member 10 Antibodies (59) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DNAJC10 54431 Q8IXB1
DNAJC10 66861 Q9DC23
DNAJC10 295690 Q498R3
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Top DnaJ (Hsp40) Homolog, Subfamily C, Member 10 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$4,229.50
Details

DNAJC10 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10) Interaction Partners

Human DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10) interaction partners

  1. ERdj5 is a member of the proteostasis network that regulates rod opsin biogenesis and supports a role for disulfide bond formation/reduction in rod opsin biogenesis and disease.

  2. ERdj5, by binding to Sel1L (show SEL1L Proteins), triggers BiP (show GDF10 Proteins)-Cholera toxin interaction proximal to the Hrd1 (show SYVN1 Proteins) complex; postulate this scenario enables the Hrd1 (show SYVN1 Proteins)-associated retrotranslocation machinery to capture the toxin efficiently once the toxin is released from BiP (show GDF10 Proteins)

  3. ERdj5 acts as the endoplasmic reticulum reductase, both preparing misfolded proteins for degradation and catalyzing the folding of proteins that form obligatory non-native disulfides.

  4. ERdj5 is a ubiquitous protein localized in the ER and is particularly abundant in secretory cells. Its transcription is induced during ER stress, suggesting potential roles for ERdj5 in protein folding and translocation across the ER membrane.

  5. JPDI may have roles in folding of some proteins in the ER, chaperoning by BiP (show GDF10 Proteins) and formation of proper disulfide bonds

  6. The organization of the functional motifs of hMTHr suggests that the protein might be a member of a molecular chaperone (show HSP90AA1 Proteins) family.

  7. ERdj4 and ERdj5 promote turnover of misfolded SP-C and this activity is dependent on their ability to stimulate BiP ATPase activity.

  8. study found that an endoplasmic reticulum (ER) protein ERdj5 had a reductase activity, cleaved the disulfide bonds of misfolded proteins & accelerated ER-associated degradation through its physical and functional associations with EDEM (show EDEM1 Proteins) & BiP (show GDF10 Proteins)

  9. ERdj5 decreases neuroblastoma (show ARHGEF16 Proteins) cell survival by down-regulating the UPR, raising the possibility that this protein could be a target for anti-tumor approaches.

Mouse (Murine) DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10) interaction partners

  1. study identified the redox partners of ERdj5 from the mouse epididymis; findings show that ERdj5 interacted with two of the identified proteins via formation of intermolecular disulfide bond

  2. Data suggest that ERdj5 contributes to ER protein quality control in the salivary gland.

  3. JPDI may have roles in folding of some proteins in the ER, chaperoning by BiP (show HSPA5 Proteins) and formation of proper disulfide bonds

  4. study found that an endoplasmic reticulum (ER) protein ERdj5 had a reductase activity, cleaved the disulfide bonds of misfolded proteins & accelerated ER-associated degradation through its physical and functional associations with EDEM (show EDEM1 Proteins) & BiP (show HSPA5 Proteins)

DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10) Protein Profile

Protein Summary

This gene encodes an endoplasmic reticulum co-chaperone which is part of the endoplasmic reticulum-associated degradation complex involved in recognizing and degrading misfolded proteins. The encoded protein reduces incorrect disulfide bonds in misfolded glycoproteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with DNAJC10

  • DnaJ (Hsp40) homolog, subfamily C, member 10 (DNAJC10)
  • DnaJ (Hsp40) homolog, subfamily C, member 10 (dnajc10)
  • DnaJ (Hsp40) homolog, subfamily C, member 10 (Dnajc10)
  • 1200006L06Rik protein
  • D2Ertd706e protein
  • dnajc10 protein
  • ERdj5 protein
  • JPDI protein
  • MTHr protein
  • PDIA19 protein
  • zgc:162218 protein

Protein level used designations for DNAJC10

DnaJ homolog , DnaJ (Hsp40) homolog, subfamily C, member 10 , dnaJ homolog subfamily C member 10 , ER-resident protein ERdj5 , J-domain-containing protein disulfide isomerase-like protein , macrothioredoxin , protein disulfide isomerase family A, member 19 , endoplasmic reticulum DnaJ-PDI fusion protein 1 , j domain-containing PDI-like protein , j domain-containing protein disulfide isomerase-like protein

GENE ID SPECIES
459799 Pan troglodytes
539876 Bos taurus
549679 Xenopus (Silurana) tropicalis
557858 Danio rerio
705787 Macaca mulatta
100173742 Pongo abelii
54431 Homo sapiens
66861 Mus musculus
295690 Rattus norvegicus
424115 Gallus gallus
478826 Canis lupus familiaris
613403 Bos taurus
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