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DnaJ (Hsp40) Homolog, Subfamily C, Member 5 (DNAJC5) ELISA Kits

DNAJC5 is a member of the J protein family. Additionally we are shipping DNAJC5 Antibodies (100) and DNAJC5 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human DNAJC5 DNAJC5 80331 Q9H3Z4
DNAJC5 13002 P60904
Anti-Rat DNAJC5 DNAJC5 79130 P60905
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Top DNAJC5 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Mouse 7 pg/ml 28-1800 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details

More ELISA Kits for DNAJC5 Interaction Partners

Fruit Fly (Drosophila melanogaster) DnaJ (Hsp40) Homolog, Subfamily C, Member 5 (DNAJC5) interaction partners

  1. This review summarizes studies that elucidate the neuroprotective role of Drosophila CSP, which is critical for maintaining neurotransmitter release and preventing neurodegeneration.

  2. these data suggest that CSP promotes synaptic growth and evoked neurotransmitter release by mechanistically independent signaling pathways

  3. study found dHIP14 to be an essential maternal effect (show NLRP5 ELISA Kits) gene required for photoreceptor synaptic transmission and for proper in vivo expression of the palmitoylated presynaptic proteins SNAP-25 (show SNAP25 ELISA Kits) and cysteine string protein

  4. Our data indicate that HIP14 controls neurotransmitter release by regulating the trafficking of CSP to synapses.

Xenopus laevis DnaJ (Hsp40) Homolog, Subfamily C, Member 5 (DNAJC5) interaction partners

  1. csp interaction with Hsc 70 (show HSPA8 ELISA Kits) molecular chaperones is vital for regulated secretion in Xenopus oocytes

Human DnaJ (Hsp40) Homolog, Subfamily C, Member 5 (DNAJC5) interaction partners

  1. Missense mutations in DNAJC5 does not play a major role in PD in the Chinese population.

  2. Results indicate of a p.L116del mutation in DNAJC5 from families with autosomal dominant Kufs disease.

  3. Palmitoylation-induced aggregation of mutant CSP-alpha proteins may underlie the development of adult-onset neuronal ceroid lipofuscinosis (show CLN6 ELISA Kits)

  4. association of DNAJC5 mutations with autosomal dominant Kufs disease

  5. This is the first replication study of the identification of DNAJC5 as the disease-causing gene for autosomal dominant ANCL. The identification of the novel gene in ANCL will allow us to gain a better understanding of the pathological mechanism of ANCLs

  6. First evidence that CSP and HSP70 (show HSP70 ELISA Kits), and their interactions with MARCKS (show MARCKS ELISA Kits), are involved in mucin (show SLC13A2 ELISA Kits) secretion from airway epithelium.

  7. Csp not only regulates the exit of CFTR from the ER, but this action is accompanied by Hsc70/Hsp70 and CHIP-mediated CFTR degradation.

  8. Csp has a role in regulated CFTR (show CFTR ELISA Kits) trafficking at the plasma membrane. [CYSTEINE STRING PROTEIN]

  9. Cysteine string protein inhibits N-type calcium channels, but is blocked by mutant huntingtin (show HTT ELISA Kits)

  10. CSP modulates G protein function by preferentially targeting the inactive GDP-bound form of G alpha(s (show GNAS ELISA Kits)) and promoting GDP/GTP (show AK3 ELISA Kits) exchange; the guanine nucleotide exchange activity of full-length CSP is regulated by Hsc70 (show HSPA8 ELISA Kits)-SGT (show SGTA ELISA Kits)

Mouse (Murine) DnaJ (Hsp40) Homolog, Subfamily C, Member 5 (DNAJC5) interaction partners

  1. The mRNA and protein expression of CSP1 (show RCAN1 ELISA Kits) was elevated in 3T3-L1 adipocytes in insulin (show INS ELISA Kits) resistant states caused by high levels of palmitate and chronic insulin (show INS ELISA Kits) exposure.

  2. gamma-Synuclein (show SNCG ELISA Kits) binds synaptic vesicles but is unable to rescue the phenotype of CSPalpha-deficient mice.

  3. Using hippocampal cultures, study shows that CSPalpha regulates the stability of client proteins and synaptic vesicle number. Analysis of CSPalpha-dynamin 1 (show DNM1 ELISA Kits) interactions reveals unexpectedly that CSPalpha regulates the polymerization of dynamin 1 (show DNM1 ELISA Kits).

  4. Study shows that cysteine string protein-alpha is required to maintain the size of the releasable pool of synaptic vesicles in motorneurons, presumably by conveying stability to SNAP-25 (show SNAP25 ELISA Kits).

  5. findings suggest that the neurodegeneration in CSPalpha KO mice is primarily produced by defective SNAP-25 (show SNAP25 ELISA Kits) function, which causes neurodegeneration by impairing SNARE (show VTI1B ELISA Kits)-complex assembly

  6. Data indicate that Cspalpha interacts with Syt9, and such a complex may be relevant in the calcium-mediated control of a late stage of exocytosis by triggering the specific recruitment of a folding catalyst at the fusion point.

  7. Data show that deletion of CSPalpha produces an abnormal SNAP-25 (show SNAP25 ELISA Kits) conformer that inhibits SNARE (show VTI1B ELISA Kits)-complex formation, and is subject to ubiquitylation and proteasomal degradation.

  8. CSPalpha is not essential for the normal operation of Ca2 (show CA2 ELISA Kits)+ channels or exocytosis but acts as a presynaptic chaperone that maintains continued synaptic function. Its deletion causes postnatal lethality of knockout mice.

  9. Tonically active ribbon synapses in retina are particularly sensitive to the deletion of CSPalpha and that expression of at least one CSP isoform is essential to protect such tonically active synapses from neurodegeneration.

  10. palmitoylation of CSP is enhanced specifically by co-expression of the Golgi-localized palmitoyl transferases DHHC3, DHHC7, DHHC15, or DHHC17

DNAJC5 Antigen Profile

Antigen Summary

This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8.

Gene names and symbols associated with DNAJC5

  • Cysteine string protein (Csp) antibody
  • cysteine string protein (Csp) antibody
  • cysteine string protein (SJAG_04371) antibody
  • DnaJ (Hsp40) homolog, subfamily C, member 5aa (dnajc5aa) antibody
  • DnaJ (Hsp40) homolog, subfamily C, member 5 gamma (dnajc5g) antibody
  • cysteine string protein (Tsp_06120) antibody
  • DnaJ (Hsp40) homolog, subfamily C, member 5 (DNAJC5) antibody
  • DnaJ (Hsp40) homolog, subfamily C, member 5 (Dnajc5) antibody
  • DnaJ (Hsp40) homolog, subfamily C, member 5 beta (dnajc5b) antibody
  • 2610314I24Rik antibody
  • ab49 antibody
  • anon-WO02059370.50 antibody
  • AU018536 antibody
  • cb995 antibody
  • CG6395 antibody
  • CLN4 antibody
  • CLN4B antibody
  • Csp antibody
  • csp-beta antibody
  • csp29 antibody
  • csp32 antibody
  • Cys antibody
  • D-CSP antibody
  • D.M.CSP antibody
  • Dcsp antibody
  • DCSP-1 antibody
  • Dmel\\CG6395 antibody
  • DNAJC5 antibody
  • DNAJC5A antibody
  • GB10835 antibody
  • l(3)03988 antibody
  • MAB ab49 antibody
  • NCL antibody
  • zgc:92898 antibody

Protein level used designations for DNAJC5

CG6395-PA , CG6395-PB , CG6395-PC , CG6395-PD , CG6395-PE , Csp-PA , Csp-PB , Csp-PC , Csp-PD , Csp-PE , cystein string protein , cysteine string protein , cysteine string protein 3 , cysteine-string protein , DnaJ (Hsp40) homolog, subfamily C, member 5 , cysteine string protein alpha , dnaJ homolog subfamily C member 5 , CSP , xcsp

GENE ID SPECIES
40459 Drosophila melanogaster
100159337 Acyrthosiphon pisum
724965 Apis mellifera
7050923 Schizosaccharomyces japonicus yFS275
386768 Danio rerio
447223 Xenopus laevis
10911532 Trichinella spiralis
448068 Xenopus (Silurana) tropicalis
485982 Canis lupus familiaris
80331 Homo sapiens
13002 Mus musculus
79130 Rattus norvegicus
282216 Bos taurus
399123 Xenopus laevis
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