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Docking Protein 4 Proteins (DOK4)

DOK proteins are enzymatically inert adaptor or scaffolding proteins. Additionally we are shipping DOK4 Antibodies (63) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DOK4 55715 Q8TEW6
DOK4 114255 Q99KE3
Rat DOK4 DOK4 361364  
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Top DOK4 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,918.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

DOK4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Docking Protein 4 (DOK4) Interaction Partners

Human Docking Protein 4 (DOK4) interaction partners

  1. the current study have explored in more detail the structure and function of the Dok-4 PTB (show PTBP1 Proteins) domain.

  2. DOK4 expression in human T cells has been demonstrated, and its genomic structure has been predicted.

  3. IRS5/DOK4 and IRS6/DOK5 (show DOK5 Proteins) represent two new signaling proteins with potential roles in insulin (show INS Proteins) and IGF-1 (show IGF1 Proteins) action

  4. Results suggest that Dok-4, through activation of the Rap1 (show RABGEF1 Proteins)-ERK1/2 pathway, regulates GDNF (show GDNF Proteins)-mediated neurite outgrowth during neuronal development.

  5. IRS-5 (DOK4) is significantly upregulated in 90% of examined clear cell RCCs. Studies on this gene has shown that it is regulated through chromatin remodeling in kidney cells

  6. Epigenetic regulation of DOK4 expression is associated with non-small-cell lung cancer.

  7. Dok-4 represents a novel negative regulator of T cells

Mouse (Murine) Docking Protein 4 (DOK4) interaction partners

  1. the current study have explored in more detail the structure and function of the Dok-4 PTB (show PTBP1 Proteins) domain.

  2. Dok-4 is a constitutively membrane-localized adapter molecule that may function as an inhibitor of tyrosine kinase (show TYRO3 Proteins) signaling in epithelial cells.

DOK4 Protein Profile

Protein Summary

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.

Gene names and symbols associated with Docking Protein 4 Proteins (DOK4)

  • docking protein 4 (DOK4)
  • docking protein 4 (Dok4)
  • docking protein 4-like (LOC618756)
  • DOK4 protein

Protein level used designations for Docking Protein 4 Proteins (DOK4)

IRS-5 , IRS5 , downstream of tyrosine kinase 4 , insulin receptor substrate 5 , docking protein 4

GENE ID SPECIES
100052258 Equus caballus
55715 Homo sapiens
114255 Mus musculus
361364 Rattus norvegicus
430610 Gallus gallus
487264 Canis lupus familiaris
100620637 Sus scrofa
100172743 Pongo abelii
618756 Bos taurus
Selected quality suppliers for DOK4 Proteins (DOK4)
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