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DRD4 encodes the D4 subtype of the dopamine receptor. Additionally we are shipping DRD4 Antibodies (123) and DRD4 Kits (24) and many more products for this protein.
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Authors examined the possible association between DRD4 allelic variation and three measures of juvenile behavior. Five different DRD4 alleles (5R, 5.5R, 6R, 6.5R, and 7R) were identified in the subject population.
DRD4 gene expression reduction in breast cancer patients after spiritual intervention
Polymorphisms of the DRD4 gene appear to be associated with SSRI treatment response in Chinese MDD patients.
Findings provide evidence of an epistatic interaction between polymorphisms acting within the dopamine system (specifically upon DRD4 and COMT (show COMT Proteins) activity) and likelihood of comorbid substance abuse in women with bulimia-spectrum eating disturbances
Community disadvantage interacted with parental DRD4 status to predict low levels of protective parenting. Protective parenting, in turn, interacted with youth DRD4 status to forecast increases in youth's planful future orientations, a proximal influence on changes in risk behavior.
DRD4 and SLC6A3 (show SLC6A3 Proteins) gene polymorphisms may have a role in food intake and nutritional status in children in early stages of development
There may be a specific molecular pathway by which the DRD4-521T genotype alters ACC electrophysiology and thereby predicts the level of problematic substance use in undergraduates.
There were no significant interactions for DRD4 with parental support and psychological control with respect to development of adolescent delinquency.
In contrast to previous results, we observed no significant interactions between DRD4 and childhood adversity in the etiology of alcohol dependence symptoms during emerging and young adulthood.
findings thus reveal unreported structural determinants of the mutated DRD4 receptor and provide a robust framework for design of effective novel drugs.
the putative involvement of DAT1 and DRD4 genes in the aetiology of Attention-deficit hyperactivity disorder with a main role in modulation of key dimensions of the disorder
The G-protein coupled receptor, DRD4, requires ARR1 and ARR4 for desensitization and internalization.
This study demonstrated that dopamine D4 receptor gene has an important role in increased exploratory and anxiolytic behavior only in males and these behaviors were positively correlated with increased alcohol consumption.
Contrast sensitivity is reduced in Drd4-/- mice.
dopaminergic modulation of early long-term potentiation in stratum oriens occurs through NMDA receptors containing NR2B (show GRIN2B Proteins) subunits via D4Rs
Data demonstrate that stimulating the dopamine Dreceptor is essential in maintaining the normal rhythmic production of adenylyl cyclase 1 (show ADCY1 Proteins) from transcript to enzyme activity.
This study demonistrated that the dopamine D4 receptor is the role of attention.
The result of this study demonistrated that the dopamine drd4 receptor appears to be important for specific exploration.
no connection between analysed polymorphism of genes: DRD2 (show DRD2 Proteins), DRD3 (show DRD3 Proteins), DRD4, DAT (show SLC6A3 Proteins), COMT (show COMT Proteins) and schizophrenia was stated.
This result suggests an effect of 5-HTTLPR (show SLC6A4 Proteins) on externalizing behavior in the presence of DRD4 7r but no effect in its absence.
D4R signaling is essential for the expression of juvenile hyperactivity and impaired behavioral inhibition, relevant features present in this attention deficit disorder-like mouse model.
This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats\; the sequence shown contains four repeats.
dopamine D4b receptor
, dopamine receptor D4
, D(2C) dopamine receptor
, D(4) dopamine receptor
, dopamine D4 receptor
, seven transmembrane helix receptor
, d(2C) dopamine receptor
, dopamine receptor 4