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DRD5 encodes the D5 subtype of the dopamine receptor. Additionally we are shipping Dopamine Receptor D5 Kits (27) and Dopamine Receptor D5 Proteins (6) and many more products for this protein.
Showing 10 out of 74 products:
Mouse (Murine) Polyclonal DRD5 Primary Antibody for DB, EIA - ABIN492916
Farooqui, Brock, Hamdi, Prasad: Antibodies against synthetic peptides predicted from the nucleotide sequence of D2 receptor recognize native dopamine receptor protein in rat striatum. in Journal of neurochemistry 1991
Show all 3 references for ABIN492916
Human Polyclonal DRD5 Primary Antibody for DB, EIA - ABIN492918
Sakata, Farooqui, Prasad: Post-transcriptional regulation of loss of rat striatal D2 dopamine receptor during aging. in Brain research 1992
Show all 3 references for ABIN492918
Human Polyclonal DRD5 Primary Antibody for ELISA, WB - ABIN334388
Daly, Hawi, Fitzgerald, Gill: Mapping susceptibility loci in attention deficit hyperactivity disorder: preferential transmission of parental alleles at DAT1, DBH and DRD5 to affected children. in Molecular psychiatry 1999
Human Polyclonal DRD5 Primary Antibody for IF (p), IHC (p) - ABIN733868
Xu, Wang, Chen, Chen, Li, Shao, Li, Lu, Zhou: Dopamine D1 receptor activation induces dehydroepiandrosterone sulfotransferase (SULT2A1) in HepG2 cells. in Acta pharmacologica Sinica 2014
Mouse (Murine) Polyclonal DRD5 Primary Antibody for IHC, WB - ABIN1742090
Hollon, Bek, Lachowicz, Ariano, Mezey, Ramachandran, Wersinger, Soares-da-Silva, Liu, Grinberg, Drago, Young, Westphal, Jose, Sibley: Mice lacking D5 dopamine receptors have increased sympathetic tone and are hypertensive. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2002
Conserved residues in intracellular loop 1 and transmembrane region 2 of DRD1 (show DRD1 Antibodies) and DRD5 are essential in ligand binding and signal transduction.
D1R and D5R colocalize in renal proximal tubule cells and physically interact in second messenger coupling pathways and heterologous receptor interaction between the two receptors.
This study shown DRD5 to be the risk factor for attention deficit/hyperactivity disorder.
LRs are essential not only for the proper membrane distribution and maintenance of AC5/6 activity but also for the regulation of D1R- and D5R-mediated AC signaling.
We found significant negative correlations regarding the expression of the genes COMT, MAOB, DRD4, DRD5 and FOS, indicating that increased schizotypy coincides with higher levels of dopaminergic dysregulation on the mRNA-level.
This study demonistrated that Lymphocyte DR D5 is reduced in MS and IFN-beta (show IFNB1 Antibodies) restores their expression and responsiveness.
Constitutive D5R signalling up-regulated expression of Na,K-ATPase (show ATP1A1 Antibodies)-alpha2 and NHE-2 (show SLC9A2 Antibodies), increasing glucose metabolism. Agonist treatment increased this and also upregulated NHE-3 (show SLC9A3 Antibodies).
Our find-ings suggest that common genetic variations of DRD5 are likely to con-tribute to genetic susceptibility to paranoid schizophrenia in Han Chinese
confirmed at protein level the previously reported increased expression of DRD5 and the variably aberrant expression of ADORA2A (show ADORA2A Antibodies), in Lesch-Nyhan disease lymphocytes
SNX1 (show SNX1 Antibodies) has a crucial role in D(5)R trafficking and SNX1 (show SNX1 Antibodies) depletion results in D(5)R dysfunction and thus may represent a novel mechanism for the pathogenesis of essential hypertension
CCKBR and D5R synergistically interact in the kidney, which may contribute to the maintenance of normal sodium balance following an increase in sodium intake
We suggest that the ability of the dopamine D5 receptor to negatively regulate the renal NADPH oxidase (show NOX4 Antibodies) activity and AT1R (show AGTRAP Antibodies) function may have important implications in the pathogenesis of salt-sensitive blood pressure.
This study demonstrated that D5R stimulation contributes to an efficient CD4 (show CD4 Antibodies)(+)T-cell-induced early ERK1/2 (show MAPK1/3 Antibodies) phosphorylation, and differentiation.
The renal D5R protein upregulation was not caused by increased transcription because renal mRNA expression of D5R was similar in D3(-/-) and D3(+/+) mice.
This study demonistrated that the dopamine D5 receptor as a regulator of BDNF (show BDNF Antibodies) and Akt (show AKT1 Antibodies) signalling in rodent prefrontal cortex.
By contributing to CD4(+) T cell activation and differentiation to Th17 phenotype, D5R expressed on DCs is able to modulate the development of an autoimmune response in vivo.
We propose that ciliary DR5 (show TNFRSF10B Antibodies) has functional chemo- and mechano-sensory roles in endothelial cells.
Dopamine D5 receptor knockout mice were used to study the role of D5 dopamine receptors in the locomotor-discriminative effects of cocaine.
D1 and D5 receptors exert distinct actions on both activity-dependent synaptic plasticity and spontaneous motor activity. Accordingly, ablation of D1 receptors disrupted corticostriatal LTP (show SCP2 Antibodies), whereas pharmacological blockade of D5 receptors prevented LTD
these data provide evidence that functional D1/D5 receptors are expressed in the internal globus pallidus and the substantia nigra pars (show EPRS Antibodies) reticulata in both normal and parkinsonian states in monkeys
In the basolateral amygdala, the D1R (show DRD1 Antibodies) subtypes colocalize in dendritic spines and terminals, with D(5) predominant in terminals. There were similarities between the primates and rats, such as more prominent D(5) localization to presynaptic structures.
This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2.
dopamine receptor D5
, D(1B) dopamine receptor-like
, D(1B) dopamine receptor
, D1beta dopamine receptor
, d(5) dopamine receptor
, dopamine D5 receptor
, dopamine receptor D1B
, dopamine receptor 5
, D(5) dopamine receptor
, D1b dopamine receptor
, D5 dopamine receptor
, dopamine D1B receptor