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Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Additionally we are shipping DRAXIN Proteins (7) and DRAXIN Kits (1) and many more products for this protein.
Showing 10 out of 49 products:
Human Polyclonal DRAXIN Primary Antibody for EIA, IF - ABIN1450058
Miyake, Takahashi, Miwa, Shimada, Konishi, Itoh: Neucrin is a novel neural-specific secreted antagonist to canonical Wnt signaling. in Biochemical and biophysical research communications 2009
Show all 3 references for ABIN1450058
Cow (Bovine) Polyclonal DRAXIN Primary Antibody for DB, EIA - ABIN492936
Zhang, Henzel: Signal peptide prediction based on analysis of experimentally verified cleavage sites. in Protein science : a publication of the Protein Society 2004
Show all 2 references for ABIN492936
results suggest that draxin functions as a repulsive guidance cue for PCN (show PCNT Antibodies) migration. However, we observed no significant differences in PCN (show PCNT Antibodies) distribution between draxin(-/-) and wild type embryos.
Neucrin is a unique secreted Wnt (show WNT2 Antibodies) antagonist that is predominantly expressed in developing neural tissues.
These results suggest that draxin from neocortical neurons controls thalamocortical projections into the neocortex, and that this effect is mediated through the DCC (show DCC Antibodies) and Neo1 (show NEO1 Antibodies) receptors.
Study elucidates for the first time, molecular events in draxin repulsion and links draxin and DCC to MAP1B to axon guidance cue signaling.
The combinatorial guidance activities of draxin and Tsukushi (show TSKU Antibodies) are essential for forebrain commissure formation
Draxin interacts with subnanomolar affinity to the netrin receptor DCC (show DCC Antibodies), in a region of DCC (show DCC Antibodies) distinct from its netrin-binding domain.
These results suggest that draxin functions as an inhibitory guidance cue for olfactory bulb axons and indicate its contribution to the formation of the lateral olfactory tract.
This study found that draxin, a repulsive axon guidance cue, was widely expressed in the developing hippocampus and draxin deficient mice possessed a smaller hippocampus.
draxin knockout mice showed defasciculation of spinal cord commissural axons & absence of all forebrain commissures; draxin is a previously unknown chemorepulsive axon guidance molecule (show NTNG1 Antibodies) required for the development of spinal cord & forebrain commissures
Draxin-derived 22-aa fragment is sufficient for binding to Ntn1a.
Neucrin is a unique secreted Wnt (show WNT2 Antibodies) antagonist that is predominantly expressed in developing neural tissues and plays roles in neural development in zebrafish.
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord and cortical explants in vitro. Binds directly to the neurites and growth cones.
dorsal inhibitory axon guidance protein
, dorsal repulsive axon guidance protein
, neural tissue-specific cysteine-rich protein