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Dorsal Inhibitory Axon Guidance Protein Proteins (DRAXIN)

Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Additionally we are shipping DRAXIN Antibodies (45) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DRAXIN 374946 Q8NBI3
DRAXIN 70433 Q6PAL1
DRAXIN 691317  
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Top DRAXIN Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Cells Human His tag 50 μg Log in to see 16 Days
$382.80
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,836.17
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Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,871.00
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Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,911.33
Details
HOST_Escherichia coli (E. coli) Chicken Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
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DRAXIN Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

Rat (Rattus)

More Proteins for Dorsal Inhibitory Axon Guidance Protein (DRAXIN) Interaction Partners

Human Dorsal Inhibitory Axon Guidance Protein (DRAXIN) interaction partners

  1. results suggest that draxin functions as a repulsive guidance cue for PCN migration. However, we observed no significant differences in PCN distribution between draxin(-/-) and wild type embryos.

  2. Neucrin is a unique secreted Wnt (show WNT2 Proteins) antagonist that is predominantly expressed in developing neural tissues.

Mouse (Murine) Dorsal Inhibitory Axon Guidance Protein (DRAXIN) interaction partners

  1. These results suggest that draxin from neocortical neurons controls thalamocortical projections into the neocortex, and that this effect is mediated through the DCC (show DCC Proteins) and Neo1 (show NEO1 Proteins) receptors.

  2. Study elucidates for the first time, molecular events in draxin repulsion and links draxin and DCC to MAP1B to axon guidance cue signaling.

  3. The combinatorial guidance activities of draxin and Tsukushi (show TSKU Proteins) are essential for forebrain commissure formation

  4. Draxin interacts with subnanomolar affinity to the netrin receptor DCC (show DCC Proteins), in a region of DCC (show DCC Proteins) distinct from its netrin-binding domain.

  5. These results suggest that draxin functions as an inhibitory guidance cue for olfactory bulb axons and indicate its contribution to the formation of the lateral olfactory tract.

  6. This study found that draxin, a repulsive axon guidance cue, was widely expressed in the developing hippocampus and draxin deficient mice possessed a smaller hippocampus.

  7. draxin knockout mice showed defasciculation of spinal cord commissural axons & absence of all forebrain commissures; draxin is a previously unknown chemorepulsive axon guidance molecule (show NTNG1 Proteins) required for the development of spinal cord & forebrain commissures

  8. Neucrin is a unique secreted Wnt (show WNT2 Proteins) antagonist that is predominantly expressed in developing neural tissues.

Zebrafish Dorsal Inhibitory Axon Guidance Protein (DRAXIN) interaction partners

  1. Draxin-derived 22-aa fragment is sufficient for binding to Ntn1a.

  2. Neucrin is a unique secreted Wnt (show WNT2 Proteins) antagonist that is predominantly expressed in developing neural tissues and plays roles in neural development in zebrafish.

DRAXIN Protein Profile

Protein Summary

Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord and cortical explants in vitro. Binds directly to the neurites and growth cones.

Gene names and symbols associated with DRAXIN

  • chromosome 16 open reading frame, human C1orf187 (C16H1orf187)
  • chromosome 21 open reading frame, human C1orf187 (C21H1ORF187)
  • dorsal inhibitory axon guidance protein (DRAXIN)
  • dorsal inhibitory axon guidance protein (Draxin)
  • dorsal inhibitory axon guidance protein (draxin)
  • 2610109H07Rik protein
  • AGPA3119 protein
  • C1orf187 protein
  • draxin protein
  • MGC113312 protein
  • neucrin protein
  • UNQ3119 protein

Protein level used designations for DRAXIN

dorsal inhibitory axon guidance protein , dorsal repulsive axon guidance protein , draxin , neural tissue-specific cysteine-rich protein , neucrin , neucrin-like

GENE ID SPECIES
506110 Bos taurus
419492 Gallus gallus
374946 Homo sapiens
70433 Mus musculus
691317 Rattus norvegicus
619245 Danio rerio
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