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Dorsal Root Ganglia Homeobox Proteins (DRGX)

Transcription factor required for the formation of correct projections from nociceptive sensory neurons to the dorsal horn of the spinal cord and normal perception of pain (By similarity).. Additionally we are shipping DRGX Antibodies (60) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DRGX 644168 A6NNA5
Rat DRGX DRGX 252880 Q62798
DRGX 107751 Q8BYH0
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Top DRGX Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details

DRGX Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

More Proteins for Dorsal Root Ganglia Homeobox (DRGX) Interaction Partners

Zebrafish Dorsal Root Ganglia Homeobox (DRGX) interaction partners

  1. Results suggest that drg11 expression in the developing zebrafish is, like its mammalian homologous gene, predominantly localised to neurons in sensory processing areas of the embryonic nervous system and is both spatially and temporally regulated.

Mouse (Murine) Dorsal Root Ganglia Homeobox (DRGX) interaction partners

  1. The results of this study showed that Prrxl1(-/-) animal is a valuable model system for examining the genetic assembly and functional role of trigeminal lemniscal circuits in the normal control of eating in mammals.

  2. Tlx3 (show TLX3 Proteins) uses distinct mechanisms to tightly modulate Prrxl1 activity, either by controlling its transcriptional levels or by increasing Prrxl1 phosphorylation state.

  3. Prrxl1 uses distinct regulatory regions to repress its own expression in dorsal root ganglia and dorsal spinal cord.

  4. Data suggest phosphorylation at serine-119 is a determinant of Prrxl1 conformation/transcriptional activity in embryonic dorsal root ganglia and dorsal spinal cord nociceptive neurons and may regulate Prrxl1 during nociceptive system development.

  5. Prrxl1 transcription is regulated by three alternative promoters, which control the expression of three distinct Prrxl1 5'-UTR variants.

  6. Our present results point to a role for Prrxl1 in sensitization of nociceptive neurons upon inflammatory pain.

  7. Formation of whisker-related principal sensory nucleus-based lemniscal pathway requires Drg11.

  8. transcriptionally regulates DRAGON; coexpressed with DRAGON in embryonic dorsal root ganglion and spinal cord

  9. Our results demonstrate an essential role for Drg11 in the development of the mesencephalic trigeminal nucleus.

  10. DRG11 is required for the establishment of the first neuronal sensory relay along development

DRGX Protein Profile

Protein Summary

Transcription factor required for the formation of correct projections from nociceptive sensory neurons to the dorsal horn of the spinal cord and normal perception of pain (By similarity).

Gene names and symbols associated with DRGX

  • dorsal root ganglia homeobox (DRGX)
  • dorsal root ganglia homeobox (drgx)
  • dorsal root ganglia homeobox (Drgx)
  • paired related homeobox protein-like 1 (Prrxl1)
  • Drg11 protein
  • Drgx protein
  • Prrxl1 protein

Protein level used designations for DRGX

dorsal root ganglia homeobox , paired related homeobox-like 1 , dorsal root ganglion homeobox protein , dorsal root ganglia homeobox protein , drg11 , paired related homeobox protein-like 1 , paired-like homeodomain transcription factor DRG11 , paired-like homeodomain trancription factor DRG11 , dorsal root ganglion 11 , homeobox protein DRG11 , paired-like homeodomain trancription factor Drg11 , paired-related homeobox protein-like 1 , paired homeodomain protein DRG11 , paired related homeobox protein-like 1b

GENE ID SPECIES
738052 Pan troglodytes
100303573 Saccoglossus kowalevskii
560399 Danio rerio
771373 Gallus gallus
644168 Homo sapiens
607056 Canis lupus familiaris
521995 Bos taurus
252880 Rattus norvegicus
107751 Mus musculus
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