anti-Double Homeobox 4 (DUX4) Antibodies

DUX4 is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID
DUX4 22947
DUX4  
DUX4  
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Top anti-Double Homeobox 4 Antibodies at antibodies-online.com

Showing 10 out of 168 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB Host: Rabbit Target Name: DUX1 Sample Tissue: Human HCT15 Whole Cell  Antibody Dilution: 1ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ICC, IF, IHC, IHC (fro), IHC (p), SimWes, WB Immunocytochemistry/Immunofluorescence: DUX4 Antibody (P4H2) [NBP1-49552] - Detection of human DUX4 on C2C12 mouse myoblasts transfected with pCS2-DUX4. Cells were counterstained with DAPI for nuclei. Immunohistochemistry: DUX4 Antibody (P4H2) [NBP1-49552] - Analysis of DUX4 on human testis 0.1 mL Log in to see 7 to 9 Days
$408.19
Details
Human Mouse Un-conjugated ICC, IF, IHC, WB Dux4 Western Blotting on C2C12 cells 1 in 1000 copy. 100 μg Log in to see 2 to 3 Days
$383.90
Details
Human Rabbit Un-conjugated WB Host: Rabbit Target Name: DUX4 Sample Type: Ovary tumor lysates Antibody Dilution: 1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB DUX4 Antibody (Center) (ABIN655583) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the DUX4 antibody detected the DUX4 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB DUX4 Antibody (C-term) (ABIN656946) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the DUX4 antibody detected the DUX4 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, IHC (p), WB 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Mouse Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: DUX4 Antibody (P2B1) [NBP2-12886] - analysis of Mouse C2C12 cell lysate showing detection of DUX4 protein using Mouse Anti-DUX4 Monoclonal Antibody, Clone P2B1 . Primary Antibody: Mouse Anti-DUX4 Monoclonal Antibody at 1:1000. Cells transfected with pCS2+DUX4 which, contains an additional upstream start site. Immunocytochemistry/Immunofluorescence: DUX4 Antibody (P2B1) [NBP2-12886] - Tissue: C2C12 myoblast cells. Species: Mouse. Primary Antibody: Mouse Anti-DUX4 Monoclonal Antibody at 1:1000. Secondary Antibody: FITC Goat Anti-Mouse (green). Counterstain: DAPI (blue) nuclear stain. 0.1 mg Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of DUX4 / DUX10  Antibody  in HL-60 cell line lysates (35ug/lane). This demonstrates the DUX4 antibody detected the DUX4 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of DUX4 / DUX10 Antibody (C-term) in A549 cell line lysates (35ug/lane). This demonstrates the DUX4 antibody detected the DUX4 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details

DUX4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine)


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Monkey


Top referenced anti-Double Homeobox 4 Antibodies

  1. Human Monoclonal DUX4 Primary Antibody for ICC, IF - ABIN4306428 : Snider, Geng, Lemmers, Kyba, Ware, Nelson, Tawil, Filippova, van der Maarel, Tapscott, Miller: Facioscapulohumeral dystrophy: incomplete suppression of a retrotransposed gene. in PLoS genetics 2010 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Double Homeobox 4 Interaction Partners

Human Double Homeobox 4 (DUX4) interaction partners

  1. these data support a model in which DME1 and DME2 myogenic enhancers associate with the DUX4 promoter in skeletal myocytes and activate transcription when epigenetically derepressed in FSHD, resulting in the pathological misexpression of DUX4-fl.

  2. proposed that Wnt/beta-catenin signaling is important for transcriptional repression of DUX4

  3. Impact of Dux4 on p53 (show TP53 Antibodies)/p21 (show CDKN1A Antibodies) signal pathway, which controls the checkpoint in cell cycle progression. Overexpression of Dux4 increased p21 (show CDKN1A Antibodies) mRNA and protein level, while expression of p53 (show TP53 Antibodies), phospho-p53 (show TP53 Antibodies) remained unchanged.

  4. DUX4 possesses redundant mechanisms to assure nuclear entrance and that its various transcription-factor associated domains play an essential role in cell toxicity.

  5. Our findings demonstrate a role for DUX4 and repetitive elements in mammalian germline evolution and in FSHD muscular dystrophy.

  6. DUX4-expressing embryonic stem cells downregulate pluripotency markers and rapidly differentiate

  7. results suggest that DUX4 regulates overlapped and distinct groups of genes and pathways in human and mouse cells as evident by the selective up-regulation of genes involved in myogenesis and gametogenesis in human RD and immortalized cells

  8. CIC-DUX4 sarcoma represents a novel translocation-associated sarcoma with distinctive histopathologic features and rapid disease progression.

  9. DUX4 gene is activated in a small number of myonuclei, the DUX4 proteins diffuse to adjacent nuclei where they activate target genes such as PITX1 (show PITX1 Antibodies).

  10. DUX4, the primary candidate for facioscapulohumeral muscular dystrophy (FSHD) pathogenesis, is upregulated over ten-fold in FSHD myoblasts and myotubes with short telomeres, and its expression is inversely proportional to telomere length.

Double Homeobox 4 (DUX4) Antigen Profile

Protein Summary

This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that contains two homeoboxes; the repeat-array and ORF is conserved in other mammals. There was no evidence for transcription from standard cDNA libraries however RTPCR and in-vitro expression experiments indicate that the ORF is transcribed and the encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the microsatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD).

Gene names and symbols associated with DUX4

  • double homeobox, 4 (DUX4) antibody
  • double homeobox 4 (DUX4) antibody
  • DUX4 antibody
  • DUX10 antibody

Protein level used designations for DUX4

double homeobox, 4 , double homeobox protein 10 , double homeobox protein 4 , double homeobox protein 4/10

GENE ID SPECIES
471420 Pan troglodytes
750468 Pan troglodytes
22947 Homo sapiens
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