anti-Doublecortin Domain Containing 2 (DCDC2) Antibodies

DCDC2 encodes a doublecortin domain-containing family member. Additionally we are shipping DCDC2 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DCDC2 51473 Q9UHG0
DCDC2 291130 D3ZR10
DCDC2 195208 Q5DU00
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Top anti-DCDC2 Antibodies at antibodies-online.com

Showing 10 out of 96 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-DCDC2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Hela cell lysate WB Suggested Anti-DCDC2 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185538 (0.2µg/ml) staining of COS7 cell lysate transfected with full length recombinant human DCDC2 (A) and untransfected control COS7 cells (B). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-Dcdc2a Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Mouse Brain WB Suggested Anti-Dcdc2a <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Mouse Brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p), WB ABIN251255 (0.2?g/ml) staining of COS7 cell lysate transfected with full length recombinant human DCDC2 (A) and untransfected control COS7 cells (B). Primary incubation was 1 hour.  Detected by chemiluminescence. Immunohistochemistry-Paraffin: DCDC2 Antibody [ABIN251255] - Human Cerebral Cortex shows cytoplasm staining in select neurons. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Mouse Goat Un-conjugated ELISA, WB Staining of mouse brain lysate (35µg protein in RIPA buffer) with A) EB07463 (0.1µg/ml) and B) ABIN185538. Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Goat Un-conjugated ELISA 100 μg Log in to see 7 to 9 Days
$610.50
Details
Mouse Goat Un-conjugated ELISA, WB Staining of Mouse Brain lysate (35?g protein in RIPA buffer) with A) ABIN251687 (0.1?g/ml) and B)ABIN251255. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB   100 μL Log in to see 3 to 7 Days
$295.90
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Dog Goat Un-conjugated IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details

DCDC2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-DCDC2 Antibodies

  1. Mouse (Murine) Polyclonal DCDC2 Primary Antibody for ELISA, WB - ABIN251687 : McGrath, Smith, Pennington: Breakthroughs in the search for dyslexia candidate genes. in Trends in molecular medicine 2006 (PubMed)

  2. Human Polyclonal DCDC2 Primary Antibody for IF (p), IHC (p) - ABIN1385734 : Choi, de Poot, Lee, Kim, Han, Kim, Finley, Lee: Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation. in Nature communications 2016 (PubMed)

  3. Human Polyclonal DCDC2 Primary Antibody for ICC, IF - ABIN4304490 : Jeruschke, Jeruschke, DiStasio, Karaterzi, Büscher, Nalbant, Klein-Hitpass, Hoyer, Weiss, Stottmann, Weber: Everolimus Stabilizes Podocyte Microtubules via Enhancing TUBB2B and DCDC2 Expression. in PLoS ONE 2015 (PubMed)

  4. Human Polyclonal DCDC2 Primary Antibody for ELISA, IHC - ABIN251255 : Cope, Harold, Hill, Moskvina, Stevenson, Holmans, Owen, ODonovan, Williams: Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia. in American journal of human genetics 2005 (PubMed)

More Antibodies against DCDC2 Interaction Partners

Human Doublecortin Domain Containing 2 (DCDC2) interaction partners

  1. Developmental dyslexia genetic (DCDC2) and environmental factors (smoke and miscarriage) underlie ADHD traits supporting a potential pleiotropic effect.

  2. that endogenous DYX1C1 (show DYX1C1 Antibodies) localizes to the base of the cilium, whereas DCDC2 localizes along the entire axoneme of the cilium

  3. DCDC2 Polymorphism is associated with reading disability.

  4. off-target, non-immune mediated effects of the mTOR (show FRAP1 Antibodies)-inhibitor everolimus on the podocyte cytoskeleton might involve regulation of microtubules, revealing a potential novel role of TUBB2B (show TUBB2B Antibodies) and DCDC2 in glomerular podocyte development

  5. This study demonstrated that DCDC2 intron 2 deletion impair illusory visual motion perception-specifically processed by the magnocellular-dorsal (M-D) stream-is impaired in children with Developmental dyslexia.

  6. A nonsynonymous polymorphism in DCDC2 (corrected P = 0.002) and a noncoding variant in S100B (show S100B Antibodies) (corrected P = 0.016) showed a significant association with spelling performance in families of German origin.

  7. Our results reveal DCDC2a to be a deafness gene and a player in hair cell kinocilia and supporting cell (show PTPRJ Antibodies) primary cilia length regulation likely via its role in microtubule formation and stabilization.

  8. the association of DCDC2 and KIAA0319 (show KIAA0319 Antibodies) with Developmental dyslexia in Chinese population should be further validated

  9. In a population carrying a deletion in the DCDC2 gene, impaired motion perception was identified in subjects with dyslexia.

  10. DCDC2 interacts with the mediator of Wnt (show WNT2 Antibodies) signaling dishevelled (show DVL2 Antibodies), and that DCDC2 overexpression inhibits beta-catenin (show CTNNB1 Antibodies)-dependent Wnt (show WNT2 Antibodies) signaling; central role of Wnt (show WNT2 Antibodies) signaling in the pathogenesis of nephronophthisis-related ciliopathies

Mouse (Murine) Doublecortin Domain Containing 2 (DCDC2) interaction partners

  1. Behavioral results revealed deficits in rapid auditory processing, working memory and reference memory in Dcdc2(del2/del2) mice when compared with matched wild types.

  2. Results link the function of the dyslexia-associated gene Dcdc2 to spike timing through activity of N-methyl-D-aspartate receptor (show GRIN1 Antibodies) (NMDAR (show GRIN1 Antibodies))

  3. These results indicate that Dcdc2 is not required for neurogenesis, neuronal migration or differentiation in mice, but may have partial functional redundancy with doublecortin (show DCX Antibodies).

  4. heterozygous and homozygous mutations of Dcdc2 result in persistent visuo-spatial memory deficits, as well as visual discrimination and long-term memory deficits

DCDC2 Antigen Profile

Protein Summary

This gene encodes a doublecortin domain-containing family member. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. This family member is thought to function in neuronal migration where it may affect the signaling of primary cilia. Mutations in this gene have been associated with reading disability (RD) type 2, also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with DCDC2

  • doublecortin domain containing 2 (DCDC2) antibody
  • doublecortin domain containing 2B (dcdc2b) antibody
  • doublecortin domain containing 2 (Dcdc2) antibody
  • doublecortin domain containing 2a (Dcdc2a) antibody
  • AW492955 antibody
  • Dcdc2 antibody
  • DCDC2A antibody
  • RU2 antibody
  • RU2S antibody
  • zgc:123267 antibody

Protein level used designations for DCDC2

doublecortin domain containing 2 , doublecortin domain-containing protein 2 , doublecortin domain-containing protein 2-like

GENE ID SPECIES
100052480 Equus caballus
472225 Pan troglodytes
563259 Danio rerio
707472 Macaca mulatta
100352162 Oryctolagus cuniculus
100412921 Callithrix jacchus
100017769 Monodelphis domestica
51473 Homo sapiens
291130 Rattus norvegicus
488244 Canis lupus familiaris
100297854 Bos taurus
195208 Mus musculus
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