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May act as a B-cell-associated adapter that regulates B- cell antigen receptor (BCR)-signaling downstream of PI3K.. Additionally we are shipping DAPP1 Antibodies (94) and DAPP1 Proteins (6) and many more products for this protein.
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These data show that Bam32 is important for optimal anti-trypanosome IgG antibody response and suppression of disease-promoting proinflammatory cytokines.
our results identify Bam32 as a novel regulator of mast cell activation
Bam32 serves to integrate PI3K and Src kinase (show CSK ELISA Kits) signaling to promote Rac (show AKT1 ELISA Kits)-dependent B cell adhesive interactions important for Ag presentation function.
The interaction of Bam32 with Lyn (show LYN ELISA Kits) leads to Bam32 phosphorylation, which might play an important role in activating downstream signaling molecules.
Data show that Erk (show EPHB2 ELISA Kits) activation was diminished in LAT (show LAT ELISA Kits) knock-in Bam32 knockout CD4 (show CD4 ELISA Kits)(+) T cells.
Bam32 is not required for germinal center (GC) initiation, but rather functions in a late checkpoint of GC progression associated with T cell recruitment and GC B (show NPR2 ELISA Kits) cell survival.
we propose a role for Bam32 in the signaling of MHC class I molecules in professional Ag-presenting DC for the regulation of CD8 (show CD8A ELISA Kits)(+) T cell activation.
novel phosphorylation-dependent function of Bam32 in regulating Rac1 activation and actin remodeling.
BAM32 works downstream of Src (show SRC ELISA Kits) family protein tyrosine kinases and functions to link B cell antigen receptor signals with antigen-processing pathways in B cells.
May act as a B-cell-associated adapter that regulates B- cell antigen receptor (BCR)-signaling downstream of PI3K.
dual adaptor of phosphotyrosine and 3-phosphoinositides
, dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
, B-cell adapter molecule of 32 kDa
, b lymphocyte adapter protein Bam32
, dual adaptor for phosphotyrosine and 3-phosphoinositides 1