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Dual Adaptor of Phosphotyrosine and 3-phosphoinositides Proteins (DAPP1)

May act as a B-cell-associated adapter that regulates B- cell antigen receptor (BCR)-signaling downstream of PI3K.. Additionally we are shipping DAPP1 Antibodies (96) and DAPP1 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DAPP1 26377 Q9QXT1
DAPP1 27071 Q9UN19
Rat DAPP1 DAPP1 362046  
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Top DAPP1 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

DAPP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Dual Adaptor of Phosphotyrosine and 3-phosphoinositides (DAPP1) Interaction Partners

Mouse (Murine) Dual Adaptor of Phosphotyrosine and 3-phosphoinositides (DAPP1) interaction partners

  1. These data show that Bam32 is important for optimal anti-trypanosome IgG antibody response and suppression of disease-promoting proinflammatory cytokines.

  2. our results identify Bam32 as a novel regulator of mast cell activation

  3. Bam32 serves to integrate PI3K and Src kinase (show CSK Proteins) signaling to promote Rac (show AKT1 Proteins)-dependent B cell adhesive interactions important for Ag presentation function.

  4. The interaction of Bam32 with Lyn (show LYN Proteins) leads to Bam32 phosphorylation, which might play an important role in activating downstream signaling molecules.

  5. Data show that Erk (show EPHB2 Proteins) activation was diminished in LAT (show LAT Proteins) knock-in Bam32 knockout CD4 (show CD4 Proteins)(+) T cells.

  6. Bam32 is not required for germinal center (GC) initiation, but rather functions in a late checkpoint of GC progression associated with T cell recruitment and GC B (show NPR2 Proteins) cell survival.

Human Dual Adaptor of Phosphotyrosine and 3-phosphoinositides (DAPP1) interaction partners

  1. we propose a role for Bam32 in the signaling of MHC class I molecules in professional Ag-presenting DC for the regulation of CD8 (show CD8A Proteins)(+) T cell activation.

  2. novel phosphorylation-dependent function of Bam32 in regulating Rac1 activation and actin remodeling.

  3. BAM32 works downstream of Src (show SRC Proteins) family protein tyrosine kinases and functions to link B cell antigen receptor signals with antigen-processing pathways in B cells.

DAPP1 Protein Profile

Protein Summary

May act as a B-cell-associated adapter that regulates B- cell antigen receptor (BCR)-signaling downstream of PI3K.

Gene names and symbols associated with DAPP1

  • dual adaptor of phosphotyrosine and 3-phosphoinositides (DAPP1)
  • dual adaptor of phosphotyrosine and 3-phosphoinositides (dapp1)
  • dual adaptor for phosphotyrosine and 3-phosphoinositides 1 (Dapp1)
  • dual adaptor of phosphotyrosine and 3-phosphoinositides (Dapp1)
  • BAM32 protein
  • DAPP1 protein
  • zgc:111998 protein

Protein level used designations for DAPP1

dual adaptor of phosphotyrosine and 3-phosphoinositides , dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide , B-cell adapter molecule of 32 kDa , b lymphocyte adapter protein Bam32 , mDAPP1 , hDAPP1 , dual adaptor for phosphotyrosine and 3-phosphoinositides 1

GENE ID SPECIES
461398 Pan troglodytes
548440 Xenopus (Silurana) tropicalis
550386 Danio rerio
709038 Macaca mulatta
768342 Gallus gallus
26377 Mus musculus
27071 Homo sapiens
362046 Rattus norvegicus
478491 Canis lupus familiaris
533156 Bos taurus
100734806 Cavia porcellus
425211 Gallus gallus
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